Moderna

12/28/2020 around 5:30 PM she started getting itchy. Progressing as night went on. On 12/29/2020 around 5-6:00 AM you woke with hives, hoarse voice and eyes swollen. A little SOB with talking. Also had weakness and tingling. Tingling was "everywhere".. Went to ER. Treated in the ER and released. Also on this day she had additional reaction to prednisone and she found out she is allergic to this. On 12/31/2020 she had to return to ER. She was at work and not feeling the greatest. Feeling light headed on and off. Continued to work and while driving home felt confused and light headed and called co workers. Felt weak again.. Called co workers who work for ambulance service They came and checked her out and her B/P was high and having PVC's per the heart monitor Transported to ER per the ambulance. 1/1/2021 she is feeling better. Received fluids last night. ER felt it was due to receiving vaccine and then additional allergic reaction to prednisone.

injection site pain, tenderness, redness, swelling- hot to the touch. started within 3 hours. Applied ice. Headache- starting 4 hours after the vaccine. relief with tylenol but reappeared after 3-4 hours. muscle aches/fatigue- about 6 hours after the vaccine. night of the vaccine- muscle aches, fatigue, headache- took tylenol Wednesday-morning of day after vaccine- terrible headache, arm swelling redness and hot to touch, could not lift or touch arm. Extreme fatigue, could not keep my eyes open. Wednesday night-fever- started around 4pm tmax 101.0- fevers continued through the night with headache, chills and lower back pain. Extreme fatigue- went to bed around 8pm and woke up at 12pm thursday. Thursday morning- fatigue, increase in swelling and arm tenderness- injection site continued to be very hot to the touch and painful/red. Applied ice to site. Had a low grade fever 100.6 for a few hours. Tylenol taken ATC. Thursday night- no fever, headaches or fatigue but injection site cont'd to be red hot and swollen- cellutlits looking saw my PCP (wednesday prior to fever) who agreed it was a localized reaction with adverse events. Discussed with my physician at work on thursday night who stated it was a cellulitic localized reaction. fri morning- injection site improving- remains swollen, slightly itchy. less red and less warm to the touch. Beginning to form a bruise.

1 week after vaccine; redness, swelling, hard to touch, itching all around injection site with associated pain with movement and pressure on arm

7-10 days injeciton site tender painful and redness not resolving size about the size of iphone xr picture available

9:20am- mild itching on both arms and legs, No hives present 9:30am- flushed face and redness present 9:45am- pins and needle like feeling on right side of lips 10:10am-Adult Benadryl taken with Prednisone 12:54pm-3:34- Tired went to sleep 5:00pm- Shoulder pains/ aches 5:15pm- Severe headache 6:00pm-7:30pm- Chills here and there 12/31/2020 All day symptoms Lower back pain Upper back pain Ankle pains muscle Tired

Hardness and pain at injection site until present (5 days+), fever for 2 days starting day after administration

Injection site pain began about 5 hours after getting vaccine and progressively worsened. Unable to lift arm above shoulder without significant pain at about 12 hours post injection. About 13-14 hours post vaccine, began having myalgias, chills. Took ibuprofen with some improvement of symptoms, but unable to sleep due to the combination of arm pain, chills and aches. Body aches and chills were gone by the morning but the arm pain lingered, less than the night before and improving each day, still there today, but much more tolerable.

Moderna COVID-19 Vaccine EUA Lots of pain and soreness in vaccination site. Low fever(99.9F), chills, body ache, joint paint started 01/02/2021 at 4:30pm Treatment: slept and took 2 Tylenol?s. Outcome: fever down to 99.2 an hour later, body still aching

I was given the shot around 1 pm and didn?t have any reaction throughout the day besides my arm becoming sore around the injection area. I later went to bed and woke up from my sleep at 12am, shaking uncontrollably (It?s like I had the chills but the shaking was much worse that I contemplated going to the emergency room ). I felt very cold, my heart was racing,& I couldn?t catch my breath. The shaking lasted for about two hours. I finally fell back asleep and woke up again at 1am and woke up sweating, my whole body was hot and fighting off one of the worse fevers I had. Another hour passed as I tried to fall asleep and not soon after I was awoken from my sleep. At 3 am I woke up very nausea and also had to use the restroom , it felt like everything wanted to come out both ways. During this time time on the toilet I felt exhausted, dizzy, & my whole body was just aching. 2 hours later I finally fell asleep. When I awoke in the morning I still felt nauseous, had horrible body aches, & had the chills. I genuinely hope this helps someone else who May experience the same symptoms!

12/23/2020 I had diahrrea for two hours at 5pm, abnominal pain, I went to the ER and had a consult for the 24th and see if I could get my gallbladder out for previous problems, I had chest pain, they did emergency surgery that same day and they removed my gallbladder. I have a rash on my injection site, I think it's a christmas tree rash .

Arm soreness at injection site, worse than a flu shot and starting an hour after the shot and lasting approx 2 days. Increased phelgm production for approx 24 hours following injection.

Immediately after injection a nodule formed to side of injection site. Bump eventually subsided but area remained swollen and red to touch for 3 days. Now area is still red a week later and slightly itchy

When I received my vaccination some of the vaccine leaked upon the HCP removing the needle. I did not thinking anything of it and was reassured I had received the whole dose. One week after receiving vaccine my L arm noted to be very itchy. Upon looking at my arm I noticed a lemon sized red raised hive where I received the vaccine. My arm is still mildly sore and the hive has continued since noticing it. I had not noticed it previous to this.

after injection on 12/23 had red, raised, warm area lasting 3 days. On friday 1/1/2021 noticed that area came back, warm , red, raised and tender to touch. This lasted until Sunday 1/3/2021. On monday 1/4/21 the is a small amount of redness.

I woke up around 1:30 am on January 5th with a temperature of 99.9 degrees F. By 3:00 am, my temperature spiked to 100.5 degrees F. By 7 am, my temperature had returned to normal, around 98.6 degrees F and I have felt fine the rest of the day, besides some soreness at the injection site. I did not take any medications to help with the fever.

Moderna COVID-19 Vaccine EUA, Injection Site pain, headache, body aches, dizziness, light headed. Still having symptoms since they just started this morning.

Patient has some tachycardia and dizziness on the day of vaccination. Developed rash at injection site 4 days later, which is itchy, tender, and inflamed.

Pt. reported feeling itchy all over her body approximately 1 hour after receiving Moderna Vaccine. Pt. was given oral Loratadine and Benadryl 50mg at approximately 12:05 and found relief with medications but also reported a tingling sensation on both sides of cheeks that extended to her lips. At approximately 1:30 pt. reported feeling heart palpitations, Dr. ordered an EKG - results were nornal. An IV was started at this time and pt. received . IV Bolus of LR 1 L was administered. Pt. was evaluated by Dr. and discharged home at approximately 4pm that same day. Pt. symptoms did not worsen

Significant soreness, pain lifting arm, tenderness to any touch, redness around 1 in in diameter around injection site for 7 days

Site pain and swelling for 6 days after vaccination. Day 7 post vaccination; redness, itching, edema at injection site, circular area, about 5 inches in diameter. Plus swollen, painful axillary lymph nodes bilaterally.

received vaccine at 1635; 1648 rash noted on neck, right chest. Benadryl 50 mg IVP given 1652 c/o lightheadedness and palpitations Initial bp was 123/87-105 pulse and 20 respirations. At 1652 bp 151/79-128-20; 1720 nausea palpitations intermittently. 1725 134/72-104-20 and feeling fine.

woke up in middle of the night (around 1 AM) due to intense pain in injection site. Took advil and went back to bed. Woke up in the morning with extreme headache and neck pain as well as pain in injection site. Took tylenol which did not help the pain or headache. Headache worsened until about noon, at which point I could not move due to neck/arm pain and headache. Symptoms dissipated quickly away pretty quickly around 1 PM

12/24/2020 I started with a wooshing feeling immediately after the vaccine, I sat down for 15 mins and felt dizzy so I stayed another 15 mins. BP was 140 and abnormal I had juice and felt better and went back to work and I felt tingling all over my body and fainty and my legs felt very heavy. I went upstairs and my BP was 160's and heart rate was 120 and I went to the ER. My face appeared to be swollen and my tounge felt tingly and I was given fluids and benadryl and solumedrol . My BP was in the 140's I went home to get rest and I still felt tingly for a couple days. The next day I felt feverish my arm was sore and I went to doctor gave me a rx for anxiety and I stayed home and rested from work for a few days. My tinglyness subsided after the medication

12/31/20: Sore/Tender at site with some redness 1/3/2021: Redness at site with some itchiness 1/5/2021: Redness, swelling, warm to touch, and very itchy at site

Abdominal rash beginning approximately 2 hours after vaccine administration. Severe sharp right shoulder pain beginning approximately 2 hours after injection, lasting 3 days, resulting in inability to move arm away from rib cage. Excessive fatigue despite rest that has continued into Day 6, and has not recovered from this at the time of this report. Patient has been unable to participate in daily life or attend work shifts.

I had vomitting and that was moderate. The following day I was nauseous. My arm was pretty swollen and pain in the arm for two day. I had a headache that was pretty severe for two days. The third day I felt a little bit of arm soreness but I could use my arm a little better. I started having a little bit of a rash at the point of where I received the vaccine.

Injection site became itchy, and then around the entire area, shoulder area, down arm. Would lessen, then become worse again, Injection site ice packed, hydrocortisone cream applied to area at 5:45pm and 6:10pm with some relief. Small welts noted at times, but decreased with treatments. Benadryl 25mg PO at 5:15pm, Benadryl 12.5mg PO Chewable at 5:45pm and Benadryl 25mg PO at 6:10pm, all on 1/5 Repeated 25 mg PO at 8:30 on 1/6 for slight itchy HR regular, no swelling in face or tongue, no shortness of breath, no headache or visual disturbances. No nausea or vomiting, or diarrhea. Drove to home, took bath and slept well that night. Still reports general itchiness throughout body on 01/06 with some relief from benadryl.

It was noted during injection a tremendous amount of pain/stinging/burning that lasted a few minutes. About 20 minutes post injection, numbness/tingling noted in pinky/5th finger radiating down palm to wrist on same arm as injection as well as dizziness. Notified observation RNs and moved to a separate room. Mildly elevated BP but normal HR noted. No rash/hives/difficulty breathing. Numbness and tingling would migrate - most often to thumb but sometimes up entire arm. Released 1 hour after injection after no life threatening signs noted. Visited PCP the next day (1/6) at 10:15. Professional opinion that it is due to swelling from injection - now noticeable area of swelling around injection site. Recommended ice and NSAIDs.

Pain in arm and at injection site - red spot slightly larger than a quarter - tender to touch and warm

Red, tender bump at injection site started approx one week after vaccination. Circular, measures 4cmx4.5cm.

Redness, swelling, hives at injection site. Hives spread down arm and to neck, patient began trembling. Benadryl given patient sent to emergency department. Checked out in ED, HR 110 & reports nausea and headache. Nothing else abnormal. Patient observed and hives seemed to resolve.

large local injection site reaction that started the day after vaccination. Redness/swelling/warmth/itching

Burning at injection site - Start: 5 mins after injection, End: 7 mins after injection Sore arm - Start: 2 hrs after injection, End: Evening of 1/6/21 Night sweats - Night of 1/4/21 (moderate-severe), Night of 1/5/21 (mild)

Day 1: Itching began about 30-40 minutes after injection. Welts began appearing 2 hours later on arms, legs, and back. Took Benadryl 36.5 mg every 4 hours. Day 2: Woke up with hives all over body, including face , started Prednisone 10 mg x3 tablets and continued benadryl 25mg every 3-4 hours.

Fever, diaphoretic, full body muscle aches, swollen and painful lymph nodes in the right side of the neck, muscle pain at the injections site in right arm, metallic taste in mouth, fatigue, headache.

Moderna COVID-19 Vaccine EUA 12/28- vaccinated, felt like I was punched in the arm, headache 8 hours later 12/29-very bad pain at injection site and weakness in that arm, intense headache throughout the entire day, body aches especially in knees and back, exhaustion, mild nausea 12/30- pain and weakness at injection site, mild headache, mild joint pain, throat felt scratchy, mild itchy rash on waist (red/pink with some bumps, golf ball sized) 12/31- pain and weakness at injection site, mild head and joint aches 1/1- 1/5 head ache 1/5 - 1/7 itchy, puffy, red rash at injection site, tennis ball sized, hot to touch, puffiness feels firm

Moderna COVID-19 Vaccine EUA Rash at injection site on the morning of Day 6, no pain or itching, and rash went away by 7pm that night. Rash returned at injection site with itching on day 8 (today). The itching is intermittent so far today.

Stomach ache, headache, joint and muscle soreness, fatigue, extreme soreness and pain at injection site, and malaise.

Swelling of injection site was still visible after eight days. Site is approximately 4 inches in diameter, raised, firm, and warm to the touch. No fever or other noticeable symptoms.

The injection site is bright red, swollen, hot to the touch, itchy, and feels hard. There is some pain in the area and it hurts to lift my arm, and underneath in the armpit region. This is the first day this has happened since getting the injection.

fatigue and headache later in the evening of the vaccine, as well as the following day. +chills the following day. Symptoms improved day 3. Mild redness and swelling (3 cm induration) to injection site. Mild tenderness. COVID 19 test done on day 3 (day of office visit, test negative)

left arm soreness - pain radiating down arm to thumb & pain with movement (immediately after vaccination) unable to lift arm above chest height (4 hours after vaccination) mild burning sensation in upper left arm (4 hours after vaccination)

-non-raised, non-itchy, red rash on and around site of injection (asymmetrical). warm to touch. blanching. no pain. nsometimes soreness. no other notable skin changes on arm. onset 1/7/2021, 8 days after injection. noticed around 18:30. has not significantly spread at time of submitting vaers (22:20). - no treatment at this time. monitoring. -arm soreness, onset day 1 after injection until day 4 after injection. no treatment. transient, resolved day 4

1) 100.4F body temperature. Body aches and fatigue. Lasted ~12 hours. 2) Injection site soreness. Lasted ~12 hours.

Approached by vaccination staff reporting that a patient who had just received the Moderna COVID-19 vaccination was not feeling well at approximately 1:45 pm. Upon assessment, patient complained of itching all over her body, chest/throat tightness and difficulty swallowing. Called nurse to the scene to assess vital signs and patient continued to complain of above symptoms. Administered (1) epinephrine pen (0.3 mg) to patient's right thigh at 1:50 pm as 9-1-1 was called per protocol. EMS arrived and provided emergency care. Patient was transported to local ER at 2:00 pm.

DPH (after the Lot number); I started with a very severe pounding tension headache - 6:00 am; very severe fatigue; very severe arm pain at injection site. And then unable to complete daily functions: do to headache; suffered from headache - took one gram tylenol to address a low grade fever that day and the headache, too. fever subsided with tylenol. Headache was relentless; I tried 600 mg of ibuprofen as well to treat headache with no success; Started to suffer severe pain; couldn't open eyes from pressure of headache. Went to ER due to never having such a severe headache before. Tests did not show pathology that would cause headache. Was given one liter of IV fluids. Was given 25 mg of Benadryl ; 10 mg of Compazine. Along with toradol. And 20 meq of potassium. Also tested for covid and was negative. And discharged home. FOllowing day: mild headache and with resolution of left arm pain. By the 27th it felt like headache was resolved.

DPH (after the Lot number); I started with a very severe pounding tension headache - 6:00 am; very severe fatigue; very severe arm pain at injection site. And then unable to complete daily functions: do to headache; suffered from headache - took one gram tylenol to address a low grade fever that day and the headache, too. fever subsided with tylenol. Headache was relentless; I tried 600 mg of ibuprofen as well to treat headache with no success; Started to suffer severe pain; couldn't open eyes from pressure of headache. Went to ER due to never having such a severe headache before. Tests did not show pathology that would cause headache. Was given one liter of IV fluids. Was given 25 mg of benydryl ; 10 mg of compazine. Along with toradol. And 20 meq of potassium. Discharged home with two prescription migraine medications. Resolution of symptoms by 27th. COVID Test was negative result.

Employee here with COVID vaccine reaction was given the vaccine on 12/30/20 in left upper arm, noticed the area was red on 01/07/21. The area is red, swollen, warm to the touch, itching. The area measures 6 X 4.5cm borders not clearly defined. Explained conservative measures including cool compresses, if approved by PCP taking OTC IBU and antihistamines and hydrocortisone cream. Explained signs of cellulitis including skin tightness and red streaking, informed if the area worsens after trying conservative measure to go for further care with either PCP or walk in clinic. Employee verbalized understanding and agrees with plan.

Onset of symptoms was day +7. Symptoms include: red rash just below injection site. Site is warm, red, and tender. About the size of a tennis ball.

Paresthesia's throughout arms and legs over the last few days. 25 minutes after shot I had severe pins and needles (falling asleep sensation) in my left leg. Progressed to numbness/squeezing sensation in my left lower leg and numbness in L hamstring throughout the rest of the day. Wednesday I had numbness/squeezing sensation in both of my lower legs and feet and numbness throughout both hamstrings and quads. Wednesday night I had numbness throughout my right forearm after my legs started to improve slightly. Thursday I had less consistent numbness throughout my legs and forearms though still present and started getting tingling into my left hand. This morning (Friday) I have tingling occasional tingling into my lower legs and left hand.

Swelling, pain, hot to the touch, tenderness around vaccine site. Hives spreading all over body and face.

The evening of 1/7/21 she developed a temp of 100.3 with body aches, and rash on bilateral arms/ chest. Took Motrin at night and had mild temp on 1/8 of 99. and 99.2

The night of the shot I got a headache, body aches, throwing up, chills, fever, felt dizzy, my whole arm was really swollen, red and hurt. Fast forward to 1-6-2021 I have had a headache ever since and started getting a reaction at the injection site which consist of being swollen, red, a large knot under the red area, the area is really warm and sensitive to touch. I also have pain going up the left side of my neck and down my armpit/lymphatic system.

The night of the shot I got a headache, was throwing up, running a temp, chills, fever, felt dizzy and my arm was really swollen, red and hurt. Fast forward to 1-6-2021 I started getting a reaction at injection site which consisted of being swollen, red, a hard knot under the red area, really warm and sensitive to touch. I also have pain going up the left side of my neck and down my armpits/lymph nodes.

0530 - woke up. nausea, dizziness, malaise, generalized significant joint and muscle pain. Unable to stand. 0535 - crawled to Bathroom in case of vomiting, tried to stand and had near LOC (vision completely black, only able to hear), dizziness, nausea, tingling and loss of function of hands/feet acc. by extremities twitching, hyperventilating, cold sweat. 0555 - husband helped me downstairs with plan to go to ER, but I refused and wanted to sit down. violent body shakes, nausea, hyperventilating, chills, dizziness. Ear temp 98.8. Was covered in blankets and drank ~8oz water. 0630 - body shakes stopped. mild waves of nausea/generalized malaise and muscle pain/lightheadedness continued. 0730 - same symptoms, ear temp 100.1. Removed some blankets 0800 - ear temp 99.8, chills, lightheadedness, mild headache.

On Friday, January 8th, I started to feel pain/tenderness in my left armpit. It also felt firmer than my right armpit. I still feel pain/tenderness today, Saturday, January 9th. The pain is mild/moderate. I am still able to do my day-to-day activities. (I did not think it was vaccine related, so I did not make note of this during my v-safe daily check in.)

Red, raised bumps all over legs, arms and groin on week after vaccination. Bumps are itchy and welt-like

1 week following administration developed swelling to size of grapefruit, induration, redness with blanching, and itchiness

1/9/2021 experienced significant pain at injection site, by 1/10/2021 AM pain had mostly subsided to a level normally associated with vaccines. 1/10/2021 in the morning began experiencing mild intermittent numbness in left hand. 1/10/2021 afternoon began experiencing extreme low back pain when standing and walking. Cannot tie any of these symptoms to other causes. Back pain and hand numbness still present at 5 PM 1/10/2021.

Fever ranging from 100.1F-102F Body chills Bodyaches Headaches Dizziness Sorness and swelling at the injection site Took Tylenol to treat fever and bodyaches

26-year-old lady came in after she noticed she had bruises on her left hand after a CPR procedure at hospital. Patient was apparently in well health, she had received COVID-19 mRNA vaccine on January 7 at 3 PM, she has taken 2 pills with ibuprofen and tylenol for pain in right deltoid following vaccination. She was doing the CPR at 1:00 this afternoon, and she noticed that her left dorsum had some bruises. She took day off and went home and noticed that she also had bruises in both medial thighs, above the knee and some bruises in scalp. Patient presented to the Emergency Room 1/9/2021 ~6PM and platelet count was found to be 2x10^3/uL. Patient required transfusion of 7 units of platelets, steroids, and IVIG.

About 9 days (Friday 1/8) post vaccine I developed an area of redness around the injection site. It started off the size of a nickel, was slight swollen, warm, and tender to the touch. The next day (Saturday) the reddened area grew to be the size of a half dollar coin. Still warm and tender to the touch. The size was never itchy. I did not treat it with anything. The next day (Sunday) the redness was much less, the site not as warm and not tender. This is how the site remains now.

At the time of vaccination, a burning sensation was felt immediately upon injection. The person who injected the vaccine proceeded to flick the plastic tubing of the syringe while it was still in my arm, escalating the burning sensation. I let the tech know about the burning and he claimed it could be a side effect of the medication and that I would be fine. I did not suffer any medication related side effects. Left arm stiffness began about two hours after vaccination and after nearly 3 hours, I was completely unable to move my arm. Loss of shoulder posture, complete arm/hand weakness and extreme arm soreness were reported for nearly 5 days. Numbness from the injection site down to the elbow is intermittent currently. Tingling down from the shoulder joint to the fingers is constant when arm is laterally raised or when overused. The left arm is still having trouble externally/internally rotating/raising above my head, and while lifting heavy objects. I'm in the process of starting physical therapy/occupational therapy to regain normal strength and functioning without the tingling or pain. An audible clicking noise is noted that was not there previously to the injection. I am unable to exercise normally and have been functioning at a decreased work and paperwork pace at my job as a nuclear stress technician. I have also been losing days of time at work due to various doctor's appointments and diagnostic tests needed to identify the problem.

Moderna COVID-19 Vaccine EUA Hot red firm to touch welt developedat injection site6 days after vaccination. Peaked in size 24 hours after onset at approximately 3 inches across. Persisted at peak size for an additional 24 hours and then began to shrink and return to Normal color and temperature. Discoloration and temperature and firmness gone after approximately 52 hours

Noticed hives shortly after 1 woke up on 1/9/21. ~10am. Hives were white and all over legs and on back of my arms. Also had temp of 99.3..could be due to hives. Took benedryl and symptoms subsided 1/9/21 in the evening.

Redness, streaking and swelling of left arm. Diagnosed with cellulitis but not improving with Keflex. Prescribed prednisone, Benadryl and Pepcid with little improvement and seeing dermatologist today for further investigation.

Swollen deltoid and muscle soreness for 3 days following injection. Heavy fatigue on day 3. 6-7 days later, very noticeable swollen lymph nodes in left arm pit only. Tender to the touch and when adducting the arm.

Tiny pinpoint pimple looking raised bumps above elbows, shoulder, chest, and back of neck. Once discovered Benadryl 25mg was taken at 8:30 PM, and then a 2nd dose taken at 10:30 pm. Client then went to bed and did not wake up with bumps. Woke up feeling flu like symptoms Friday morning, nausea, muscle aches, headache, increased heart rate. Client does have history of migraines and anxiety which cause her heart to race. Sunday morning started with fever, cough, diarrhea, and runny nose.

Where I got the shot is still red and itchy. This has been there since I received the injection. I am unsure if it?s from the vaccine or a reaction to the band aid.

generalized itchiness; woke up with headache; feeling fatigued; anaphylactic reaction; right arm started going numb; right arm was tingling; A spontaneous report was received from a 26-year-old, female consumer who received Moderna's COVID-19 vaccine and experienced anaphylactic reaction, right arm numbness and tingling, headache, fatigue, and generalized itchiness. The patient's medical history was not provided. No relevant concomitant medications were reported. On 23 Dec 2020 prior to the onset of the events, the patient received their first of two planned doses of mRNA-1273 (Lot number: OU520A/011520A) intramuscularly in the left arm for prophylaxis of COVID-19 infection. On 23 Dec 2020, within minutes of receiving the vaccine, the patient experienced an anaphylactic reaction and was rushed to the emergency room (ER). When transported to the ER she began to experience throat swelling, redness of arms and chest, trouble breathing with lower chest pain shooting into lungs, and numbness with tingling in her right arm. Treatment for the event included epinephrine, steroids, and diphenhydramine. She was released from the ER on 23 Dec 2020. On 24 Dec 2020 patient awoke with a headache, fatigue, and generalized itchiness. Treatment for the event included ibuprofen and diphenhydramine. Action taken with the second dose of mRNA-1273 in response to the event was not reported. The outcome for the events, anaphylactic reaction, right arm numbness and tingling, were reported as resolved on 23 December 2020. The events of headache, fatigue, and generalized itchiness were considered resolving.; Reporter's Comments: This case concerns a 26-year-old female patient who received their first of two planned doses of mRNA-1273 (Lot OU520A/011520A), and who experienced the unlisted events of anaphylactic reaction, right arm numbness and tingling, and generalized itchiness, and the listed events of headache and fatigue. The events were considered to be possibly related to the vaccine due to the temporal relationship with onset on the day of vaccination.

slight headache about 30 minutes after vaccines was administered ,rash on right thigh, on Saturday Jan. 9th around 9:30PM. Rash and itchiness went away that night.

By report, EpiPen given at 1410 and repeated at 1430. VS at 1413 HR-145; BP-137/89; RR-20; O2 sat 100%. Other vitals taken through 1431; BP - 121/74; HR - 110; RR - 14 and O2 sat 100%. 1424 - "fingers on left hand tingling"; 1428 - "nausea, throat burning, breathing better, chest heaviness less tightness". 1435 - "rescue squad arrived". Reporter was not present at this event.

Initially had typical injection site soreness, fatigue and nausea. Patient reports 2 day later began developing, nasal congestion, bilateral periorbital edema and a cholinergic urticaria-like skin eruption on bilateral UE, trunk and LE's.

Initially had typical injection site soreness, fatigue and nausea. Patient reports 2 day later began developing, nasal congestion, periorbital edema and urticaria like skin eruption on bilateral UE, trunk and LE's. Evaluated in clinic 6 days later still having similar symptoms with no worsening or improvement despite OTC benadryl. No respiratory distress, fevers, or abnormal blood pressure.

My armpit lymph nodes are swollen and very tender on the same arm that my shot was given. my symptoms are not reproducible other than to palpation. There is also visible swelling. no rash or redness in the area.

New redness, swelling, tenderness that began 6 days after vaccine (4 days after previous redness/soreness ended and many days without symptoms). Frequent to constant itching at injection site. Increasing in size/severity over the past 2 days.

Patient experienced pain radiating from injection site up to neck, neck stiffness and SOA. Patient was evaluated in ED and toradol and benadryl were administered. Patient's neck pain and SOA have resolved but neck stiffness persists.

Sore arm at injection site-starting in afternoon after injection, day after injection Flu-like symptoms including muscle aches and chills - starting 8pm-12am day of injection

Within 1 hour of receiving the vaccine the patient developed asthma symptoms,dizziness, tingling in mouth and swollen tongue. She presented at a walk-in clinic and received Epi-Pen 0.3mg, Solu-Medrol and Benadryl, while there she received 2 additional doses and was transferred to the nearest ED by ambulance. At the ED she received a 4th dose of Epi-Pen 0.3mg and albuterol and DuoNeb treatments. She was admitted for observation. She went home and needed to return within 24 hours to the ED because her lips and tongue started to swell and she turned blue. She subsequently needed 3 additional doses of Epi-Pen over the next 24-48 hours. She has been on Benadryl 50mg every 6 hours and Famodine 20mg until present.

-0 to 1 day after vaccine: moderate left deltoid soreness, resolved completely -3 days after vaccine: new left axillary soreness and mild axillary lymphadenopathy -7 days after vaccine: worsening left axillary pain and lymphadenopathy with several axillary lymph nodes 1 cm in diameter. Lymphadenopathy now extending to left supraclavicular nodes and left anterior cervical chains. No other lymphadenopathy noted (I.e not bilateral). Erythema and new soreness appears over left deltoid in a 4cm patch. Seen by urgent care. Advised to report symptoms to CDC via V-safe app

1 week after administration the injection site became red and swollen and itchy. Since then I have developed hives surrounding the area on my upper arm

Beginning 1/11/2020, I began experiencing an uncomfortable sensitivity in my left axilla. I have a history of inflamed lymph nodes that occurs 1-2 times a year under the arm and in the groin, and this felt similar to those episodes. The lymph node is hard to touch and the sensitivity continues today. Today (1/13/2020), I noticed an inflamed, red patch of skin that is hot to touch over the region where the injection occurred. Additionally, I have experienced diarrhea 1-2x/day for the past two days.

Immediately after receiving the shot my left arm started to become numb and tingly, it felt like it was falling asleep. This went away after an hour. Then during the night at 1 a.m. I woke up and the same feeling of numbness was happening in both my left arm and leg. This then shifted to my right side, then just to my hands and feet. During this I was also experiencing the noted Covid vaccine side effects of fever, chills, headache, body ache, weakness, and nausea.

Rash on cheek/neck area that occurred 2 days after vaccine. Area was itchy when first popped up and now is just red with bumps

Shortly after receiving the vaccine on 1/5/20 (within several hours) the administration site was swollen, red, and warm to the touch. The swollen area was approximately the size of a silver dollar. There was also soreness around the injection site. Swelling continued through roughly 1/9/20. There was still slight redness/discoloration to the area. Soreness had subsided by 1/7/20. On the evening of 1/11/20 the area began itching. On 1/12/20 I woke up and the area was swollen again, this time worse than before, and was also slightly expanded, approximately 3.5" in diameter. It was also red and warm to the touch and was still itching. This has continued through current time.

initially she had headaches and dizziness and chills and temperature of 99.7 blushed cheeks, rash on neck 1 week later with headaches and dizziness and now accelerated heartrate that wakes her from sleep at night for 2 consecutive nights.in a row.

7 days post injection patient developed redness/hives at injection site with some itching and pain as well as warmth to the touch. Lasted for 2 days, has since resolved. Scheduled for dose #2 01/28/2021.

Arm soreness starting approximately 4 hours after injection until approximately 72 hours after injection. Mild injection site itching for the same period of time.

Diarrhea, bad rash/welts that is spreading, tired, lathargic, loss of appetite, excessive sweating and chills.

Headaches; body aches; chills; fatigue; joint pain, muscle stiffness; extreme left arm pain. Ongoing itchiness/swelling in the palms and head. This lasted greater than 2 days

I had my vaccine on 1/5/2021 and the 2 days after I had a lot of pain in my arm and fatigue which are all things I expected and they were over by Saturday 1/9. Now starting today 1/14 the area is red again and is very itchy

Moderna COVID-19 Vaccine EUA. I have a growing red spot on my arm that itches. It is developing a red ring around it. It is itchy, but doesn't hurt. It only gets swollen if I itch it and it also gets hot when I itch it. I went and saw my doctor and she prescribed me a topical steroid cream. I have been feeling lightheaded, fatigued and dizzy. That started Thursday January 7.

PATIENT NOTICED REDNESS AND A LUMP OVER THE INJECTION SITE, EXPERIENCED SOME PAIN IN UPPER ARM THAT IS IMPROVING, MAIN COMPLAINT IS ITCHINESS. USED NSAID, COLD COMPRESS AND BENDADRYL WITH EFFECTIVENESS IN DECREASING SYMTPOMS. REDNESS BORDERS MARKED ON 1/13/2021, TODAY REDNESS IS SIGNIFICANTLY DECREASED AND PT REPORTS A DECREASE IN ITCHING AND PAIN. PATIENT WAS ADVISED TO CALL HER PHYSICIAN FOR ANY FURTHER INSTRUCTIONS TO WHICH SHE DID, AT THIS TIME WILL CONTINUE TO MONITOR AND WILL CALL PHYSICIAN BACK IF SYMPTOMS GET WORSE.

Patient developed large, oval shaped red area around vaccine site 9 days after receiving first dose of Moderna covid vaccine. Low suspicion for allergic or local reaction given time frame. Treated for possible cellulitis with Keflex.

Soreness of injection site about 10 hours after injection time lasting about 2 days. 5 days after, severe pain in the underarm area 6 days after, severe pain in the underarm area in addition to pins and needles running from armpit to finger tips, sore neck and a runny nose began.

Swelling and itchiness appeared after 6 days of injection with size about 5cm diameter, now it has been two days since the reaction and the size almost doubled with heat.

Two days following administration of vaccine, there was a small, oval shaped redness at injection site about the size of index finger. However, the following day that redness resolved/barely noticeable. Yesterday (1/13/21), I noticed while showering in the morning a huge hard lump on my upper Left arm with circular redness the a little smaller than palm of my hands. The red area grew hotter throughout the day and started to swell. I applied Benadryl gel and took 2 Benadryl 25 mg each in the evening. I tried icing the area as a well. This morning, the hardness and redness are both there. No improvement but it has not worsened either. I tried going to UrgentCare to have it checked out, but was turned away because they didn?t want to be responsible for treating this. I contacted my hospital that gave me this vaccine and they directed me to another clinic, which I may or may not be able to go to because it is a little far from my location. I will continue icing, applying the gel cream, and take a Benadryl Of note, I had no prior COVID exposure. Following any vaccine, I usually get minor fever/chill (like with Flu shot) which happened with Moderna vaccine as well. But that subsided by the next evening. No fever/chills since then. I also had the commonly reported arm soreness for few days. I have pictures of how the swelling and redness looked like throughout all this as well.

localized swelling, warmth,redness and tenderness at site. Soreness within armpit. Treating with Ice and routine NSAIDS

A week and one day after I receieved the first COVID-19 vaccination, I noticed around the injection site that my arm was warm at the site, sore and swollen and had a small rash/irritaiton. Over the weekend, I took benadryl and iced my arm. The tough welt went down, but that was it. I could still feel the warmth and soreness and it was red/irritated still. I spoke with one of the nurses at my workplace and they thought it was strange that I had a reaction so late and it looked like it could be cellulitis. I have never had a reaction after a vaccination before, nor cellulitis, so I had a virtual doctors visit that following Tuesday.

About 24 hours following the Moderna vaccination I developed a red round, slightly raised, swollen, and tender spot approximately the size of a silver dollar 3 inches below the injection site. The spot resolved within 72 hours. I did not seek medical attention.

At approximately 17:15, time of discharge ,(15 minutes after vaccination) client stated that her left arm was itchy as well as both hands. Injection site area with pink hue but no hives. She also stated she felt a little something in her throat. Vital signs at this time were 143/85 BP, Heart rate 100 and O2 sat 96%. No sob. 17:19 she complained of a sensation of tongue swelling. VS 138/82, HR 90, O2 sat 96% and no SOB. Continued to monitor VS every 3 minutes. Pt offered IM Benadryl but refused. 17:22 132/87, HR 99, O2 sat 95%, 17:25 133/85 HR 90 O2 95% 17:29 132/82 HR 93, O2 sat 96%, denies any new symptoms at this time. 17:34 128/89 HR 88, O2 sat 96%, 17:38 134/85 HR 93 O2 sat 95%. States symptoms improving. 17:41 129/84 HR 93 and O2 sat95%, 17:73 133/83 HR 86 , O2 sat 96%. Pt. symptoms cont. to improve. 17:55 131/83 HR 86 O2 sat 95%. Pt states she feel better. Planes to take oral Benadryl as soon as she gets home. She was advised to consult with primary physician regarding this event and will follow up with physician if she chooses to receive a second dose of Moderna COVID 19 vaccine at her doctors office. She left at 17:56.

Increased heart rate, tingling in head & arms, lightheaded, slight rash on upper torso, swollen lymph node.

Injection site became red, lumpy, warm to touch, and itchy. Armpit also felt a dull pain with movement. The redness has not spread. Also felt nauseous and had extreme headache.

Left arm swelling, redness, induration, warmth, pain at injection site. Several days after. Treated with Keflex.

Left arm swelling, redness, induration, warmth, pain at injection site. several days after. Treated with Keflex

Patient called to report a rash on her hands, arms, and chest that is red and stings. Patient noticed the rash approximately 90 minutes after receiving her vaccination. Denies any shortness of breath or swelling in the face or neck. Writer instructed patient to take Benadryl after verifying no known drug allergies and to call a health care provider, especially if rash does not improve. Spoke to patient 1/15 AM, and she states that the rash is improving but still there after taking Benadryl.

Per patient starting just over 24 hours ago patient developed redness, warmth, itching, and welt (now size of golf ball) around the injection site. Reaction just started about 1 week after dose administration and no reported reaction prior. has taken a couple doses of benadryl which patient stated helped reduce symptoms

Pt developed itching, mild rash around injection site several minutes after injection. She also reported some itching to face bilaterally. No evidence of anaphylaxis. Symptoms improved after 1/2 hour. She refused EMS services. Band-Aid was removed and new band aid was placed on other arm where the pt then developed mild rash there as well. Suspect new allergy to bandaid adhesive. Doubt this was a reaction to the vaccine. Pt was counseled to follow up with PCP for further guidance regarding 2nd dose.

day after vaccine developed large raised red skin lesion at the injection site spontaneously went away after 2-3 days recurred again with similar appearance about 4-5 days after vaccine administration skin lesion is itchy and red, but no other symptoms

numbness and itching of L cheek (face) w/in 15 min of vaccination, numbness resolved within 15 additional minutes and itching decreased, but persisted into next day at low level. No rash was involved, just a little redness from scratching.

Erythema, induration, itching and tenderness at the injection site 7 days after receiving injection.

Had a mild headache at time of vaccine, unknowingly had a mild fever at the time, so did not take temperature. Went home to take a nap. Woke up two hours later with fever, stronger headache, chills, and muscle ache. Four hours later, the chills decreased, but the headache, fever, and muscle ache still persisted. 14 hours later (the next day), no chills, no headache, face still feels warm, but no fever. Muscle ache only in the location of the injection site.

Severe nausea with no vomiting occurring 12 hours later, also accompanied by injection site soreness.

Fever, arthralgias, dizziness, pain at injection site, shortness of breath, chest tightness, headache, fatigue, photophobia

I experienced soreness at the injection site during the first 2 days following my vaccine. The soreness went away after about 2 days. Then, on the night of January 13th, I noticed a red splotch on my skin at the injection site (8 days after injection). It was about 3 inches tall and 2 inches wide. It was not itchy or sore. I did not notice any swelling of lymph nodes in my arms/armpits. The splotch was not noticeably warmer than other spots on my arm. The redness remained through the following day, January 14th, but the redness reduced slowly throughout the day. It did not appear to spread in area. By Friday, January 15th, the redness had faded. I made an appointment at my primary care doctor's office, and they recommended I report this symptom to VAERS.

One week after injection, site had healed well. All of a sudden, the injection site became warm to the touch, swollen, itchy, painful, and hard again. This reaction was worse than the original reaction after injection.

Received first injection 1 weeks ago. The first few days I experienced normal symptoms such as pain and redness. Following that I had no symptoms. On Friday, (1/15) I noticed that the left-side lymph node in neck/collar bone area was swollen. The area felt similarly to that of a cyst. Starting Friday night, I began taking amoxicillin to prevent a bacterial infection. The swelling/cyst like bump on my neck/collarbone has decreased in size, but the vaccination sight has become very red, swollen, and itchy at times.

The next day after injection hives appeared. They last between 5-30 minutes. When they start to break they are in red itchy like the ones I get when I in-jest chocolate which I?m allergic too. They appear sporadically first on the left arm where I received the vaccine and my stomach. Today 01/16/2021 they appeared on my face, Upper back, chest and legs.

Urticaria, erythema, warmth, Itching in left arm seven days following vaccine. Rash seems to be worsening and spreading. No Initial reaction at vaccine site of Past medical history or allergic reactions.

I felt fine after the vaccination until around 3 pm when I presented with extreme fatigue. Around 6 pm, I developed a large, red bump at the injection site that was warm to the touch. The bump has reduced in size but has not gone away yet. The fatigue is better but still exists.

Noticed on 1/15 that there is still a silver dollar sized swollen lump that's hot and reddened at the injection site. I wouldn't be too concerned about such side effects except it is extremely itchy. To this day it is still reddened, swollen, warm and very itchy. In the beginning there was pain, which I took Tylenol for, but it is no longer painful. As stated before, the itching is what concerns me and how inflamed the site gets if I itch it.

01/19/2021 case presents with injection site pain one week after injection, with a low-grade fever of 100.3. Case has no prior reactions to other immunizations. Case is not pregnant, nor possessing any prior comorbities. Patient will be following with her GP at 2 for further evaluation.

1/19 4:30 PM- extreme body soreness (especially injection site/left arm), headache, chills, and felt like I had a fever (with no fever). 1/19 8:00 PM- Hallucinations began (with eyes closed and open) - started seeing unfamiliar people (faces and outlines), black and white strobing along with seeing pure red light at certain points, I could not control the hallucinations, extreme paranoia (like I was being controlled and watched), physical symptoms magically went away; however, I had pressure in my head that did not hurt like a headache. I was talking to people that were not there. I felt completely out of control. The only thing that helped was forcing myself to focus on the TV, which was extremely difficult. Symptoms started to die down around 3 AM, but did not go away. I slept for 4 hours. 1/20 8 AM- felt like and still feel like I am not in reality, I feel disassociated with my body (like its not mine), slightly out of control of my thoughts, I see subtle black and white flashing like last night but not as intense, paranoia like last night/not as intense, cant concentrate.

8 days after vaccine I noticed a round hive rash about 1 inch away from the injection site. The next day the hive rash was much larger. Rash completely went away after about 4 days.

Had chest tightness for 2 days after the vaccine, which went away on day 3. Then on day 4 a dull chest discomfort started again which I have had every since (now on day 8 post vaccine). When i woke up on day 8 post vaccine I noticed left deltoid swelling and tenderness in the arm that I received the vaccine a week ago. I only had arm swelling for 1-2 days post vaccine and then another onset on day 8 (1/20/21). Also have some left armpit tenderness 3 days ago.

Had minor side effects the night of getting the injection (i.e. sore arm, headache) But on the morning of 1/19, a full week later, when waking up and rolling onto that arm, the injection site felt bruised suddenly. (Didn't have any arm soreness after day 2). It was a small solid bump that was slightly swollen, red, and occasionally itchy

I had been lying down for 1-2 hours. When I got up, I suddenly became lightheaded and nauseous. I had to sit on the floor to steady myself. I became extremely sweaty with chills and my entire left arm (side of injection) became numb and tingly. The episode lasted approximately 20 minutes, and I was symptom-free within an hour. I never fainted or vomited.

I had slight dizziness for 20 minutes a half hour after the injection. But that's not the issue. When the lady gave me the injection, it felt like she wiggled it around in my arm. The injection itself was surprisingly painful. My arm hurt at first like I was punched in the arm on the first day (much like a flu vaccine). But then it got SIGNIFICANTLY worse the next day. I was in excruciating pain in my left upper arm where I received the vaccine. I had limited arm mobility and any movement caused agony. I couldn't sleep from the pain. I wasn't able to do my normal activities. The pain started to subside after 4 days, but had since started to get worse again. I'm in a constant state of pain. It's now impacting my mental health. I can move my arm, but not without a lot of pain.

Injection Muscle Site Reaction: Swollen hard induration/lump, Redness and Itching still a week later.

Moderna COVID-19 Vaccine EUA I received my first dose of the vaccine on Friday, January 15th. My arm was a little sore that day and the next, but it really wasn't that bad. Late on Saturday, January 16th I noticed a rash around my neckline/collar bone area that was on both sides, but more prominent on the right. The rash was red with many bumps that were not raised and were not fluid filled or blistering. The next day, Sunday (17th) the rash seemed to worsen but stay localized to that area. Monday morning (18th) I woke up with a tender right armpit indicating to me that I have a swollen lymph node. I noticed later that morning that the rash had spread bilaterally to my biceps and chest. Today is Wednesday the 20th, and while the rash looks slightly better around my neckline, the rash has now spread all over my breasts, abdomen, and a little bit to my hips. The right arm pit continues to be tender today. I took Benadryl (25 mg) Sunday night (17th) and applied hydrocortisone cream to the rash when it was just along my neckline.

Swelling of arm where vaccine was given. Arm swollen and tender. Red raised bump the seize of a silver dollar.

The day after vaccination, redness, swelling and pain onset for 4 days. By the 5th day it had subsided and my arm looked completely normal. On the 6th day I developed a patchy redness at the injection site. (today is the 6th day)

Two locations of bruising without any known cause. Bruising on left forearm, circumference of approx. 2 inches. Bruising on left ankle and on top of left foot with no known cause. Forearm bruise noticed on day after vaccine, Foot bruising noticed on Monday , 3 days after vaccine. No known causes for either of these, pain associated with forearm site. Also the night of injection chills and severe left arm pain was experienced.

pain and swelling at the injection site for a week and a half. Tiredness, headache, muscle pain, chills, joint pain, nausea, vomiting, dizzy, and fever of 104.00

within 24 hours the injection site became red, painful and swollen. I ran a fever and had body aches. Then I broke out in hives and had tightness in my chest. I then took 50mg of benadryl and it helped with the hives.

1 week after receiving the dose, I had a reaction near the injection site on my right shoulder. There is redness, swelling, itchiness, and it is warm to the touch.

8 days after vaccine I developed a large, swollen, red, itchy rash that continues to increase in size

Adverse event: Hives, redness, and itching on face, neck, chest, bilateral arms, abdomen, back, bilateral side of the groin, Bilateral legs front and back, and both tops of the feet Treatment: Bendrayl PO, 50 mg Q4 hrs, Prednisone PO 40 mg Daily, Pepcid PO 40 mg Daily. Cortisone 1% cream and Calamine lotion on affected areas Outcome: Effective, 90% of rash gone.

Fever the for two days after with injection site soreness that progressed to muscle insertion site. Then 6 days later mild fever again with marked axillary lymph node swelling and soreness around. Swelling took 2.5 days to resolve.

I developed a rash on my left arm about an inch below the injection site on January 18th 2021, 11 days after receiving the first dose of the covid vaccine. It was about the size of a nickel and the next day it grew to the size of about an inch tall and two inches wide. It was warm to the touch and splotchy. The next day it grew to about the size of the diameter of a sofa can and started itching. I had gone to the doctor the second day of the rash and they suggested that I get a covid test, which came back negative, and to put heat on it and some antibiotic ointment on it and watch it. I called the doctor the next day because it grew and was now itchy. I also had an itchy mouth. The doctor suggested that I take an antihistamine twice a day for 7 days to see if that helps. I started this last night, January 20 2021. Today is the 4th day, the rash has not grown and is no longer itchy and my mouth is no longer itchy.

Injection site has turned into red hive-like bump, approximately 1.5-2 in. in diameter, and is incredibly itchy. There has been minor itchiness since time of injection (1/14/21, 2:30 pm), nothing major. Starting 1/21/21 approximatelt 5:30-6:00 pm, noticed the injection site is now large red bump and has remained there and itchy.

Itching on sunday night starting on chest, monday morning rashes worsen and appeared on B UE and L LE. Cortisone cream applied otc not helping. Urgent care on Tuesday night and prescribed with triamcinolon.Friday, Rashes still itchy but redness slightly getting better

Rash at and around injection site 7 days after receiving. Faint arm pain also returned. Headache and more than usual tiredness for 7 days after first dose

Temporal temperature of 101.1 ^F, oral temperature of 100.8 ^F at 1025 (am) on 1/21/2021. Acetaminophen taken at 1100 (am). Tympanic temperature at 1600 was 98.7 ^F. No medication taken. Tympanic temperature at 1800 was 98.6 ^F. Nausea sudden onset at 1020 (am) on 1/21/2021. Relieved at 1200 (noon) after having lunch. Fatigue started 1/21/2021 at 0600 (am). Resolved at 1300 on 1/21/2021. Muscle aches started 1/21/2021 at 0600 (am). Resolved 1/22/2021 at 0600 (am). Chills sudden onset at 1020 (am) on 1/21/2021. Resolved 1/21/2021 by 1400. Injection site pain, localized pain on upper shoulder. Started on 1/21/2021 at 0300 (am) resolved by 1/21/2021 at 0630 (am).

Two days after the shot in Colorado I began to develop a rash on my right arm at the injection site. I had flown back to North Carolina where I am on a student rotation at a hospital the day after the vaccine (Sunday 1/17). Since then (Monday 1/18) the rash has expanded to my entire upper arm and is continuing to extend downwards. I had swelling for about a day but that went away. I had some swollen lymph nodes in my axilla and neck but they are no longer swollen. Now my arm remains extremely itching and red. I went to the ED this evening and they gave me IV Solumedrol, Pepcid, and famotidine. The rash went away except for outside of a line of demarcation we made earlier in the day. This morning I woke up with an intense itching in the arm. I rubbed my hand over it (didn?t itch it) and the redness came right back. It is continuing to expand down my arm.

One week later following my vaccination, a rather large rash appeared below the injection site. The rash was very swollen, hot and hard to touch, itchy at times, and painful with pain traveling down to the tips of my fingers. I medicated with Tylenol for four days, Zrytec for one day, applied hydrocortisone cream, and iced it with an ice pack, all without any improvement. Five days later, the pain and swelling finally went away, but the rash does still remain to this day.

0/24/2021: vaccination site a little itchy. Had a migraine at 6pm advil didn?t help. Threw up. Exceeding migraine helped. (Not 100% sure if this is related to the covid vaccine as I have had migraines in the past) 01/25/2021, a week after the vaccination, woke up with vaccination site red, hot, swollen and itchy. Was itchy the previous day but not as severe. Swelling and redness not going down with ice pack. The red circle around the vaccine site is about 2 inches. I am monitoring if it gets bigger.

8 days post vaccine I got a cellulitis infection where vaccine was administered, which needed antibiotics to treat

I noticed the day after my injection that my arm was very hot and swelling. I put ice packs on it but that only helped with the itchiness. As days have gone on its gotten larger a little larger than orange. It very red, swollen,itchy and HOT. Called my Doctor on the 23rd and she prescribed me bactrim. At this time not much change.

Patient developed wheal - like reaction at injection site the evening of receiving the vaccine. Not tender to touch. Not warm to touch. Approximate size of 4.5cm in length and 5.5cm in height. No other systemic symptoms.

12/29: severe joint pain which prevented me from working (used OTC ibuprofen for symptom management), moderate sore arm, mild headache, mild nausea 12/30: severe facial nerve pain in right cheek onset in evening when I laid down in bed followed by a pins and needles tingling feeling. Went to clinic in morning of 12/31 due to lingering facial paresthesia. Was tentatively diagnosed with a mild/incomplete Bell's Palsy or a trigeminal neuralgia. Important to note that I did NOT have facial weakness or drooping. Was advised to not get the 2nd dose of vaccine. Did not receive any prescription medications. Facial paresthesia resolved within two days.

12/29: severe joint pain which prevented me from working (used OTC ibuprofen to help manage symptoms), moderate sore arm, mild headache, mild nausea 12/30: severe facial nerve pain onset in evening while I was laying in bed, followed by pins and needles tingling feeling. Went to clinic on morning of 12/31 due to symptoms and lingering facial Paresthesia. Doctor recommended I not receive second dose of vaccine and tentatively diagnosed me with a mild/incomplete Bell?s Palsy or trigeminal neuralgia. Important to note that I did NOT experience any facial weakness or drooping. Did not receive any prescription medications. Paresthesia resolved within 2 days.

Pt got her second dose of Moderna on 01/22/2021 01/23/2021 @ 9AM pt states feeling pain in her left arm. She noticed a red bump around site of injection (deltoid) She contacted her provider yesterday and was instructed to take Benadryl. Today she still has the rash, warm at touch. She will see her provider for FU on Thursday.

1/2 hour after, right arm pain and tingling in fingers. 1 hour -2 hours after pain radiating down right arm to fingers. 12-14 hours after cold chills, sever body pain in joints, muscle, nerves. 14hours till 3 days after after sever pain still occurring along with joint stiffness, weakness, moderate fatigue. 4 days after mild overall pain with less weakness and stiffness with random times of pain radiating down different body parts.

DATA: 2:45pm: Pt scheduled for first dose Moderna COVID-19 vaccine today. Allergies and appropriateness for injection reviewed with pt prior to immunization. Pt reported bell pepper allergy only and denied prior use of epi pen. Pt received immunization at 2:45pm and waited in waiting room for 15min. 3:00pm: This RN evaluated pt for response to vaccine. Pt reported her neck was itchy, anterior neck assessed which showed multiple red "hive-like" spots. Pt was brought back to procedure room and informed that a provider would need to evaluate her. Provider evaluated pt. This RN then assisted per provider with interval vitals and assessments and medication administration of the following: 3:06pm VITALS: 123/80 bp; 73 HR 3:07pm MEDICATION: Administered per verbal of BJB solumedrol 125mg/2ml (lot AK5128, exp 10/21), 2mL administered in R dorsal gluteal. Pt had site tenderness, otherwise tolerated well. 3:07pm MEDICATION: Diphenhydramine 25mg two capsules administered to patient. Exp 1/2021. 3:20pm VITALS/LUNGS: 128/78 bp; 58 HR; 96% O2 on room air; clear lung sounds bilat. 3:35pm Pt reported feeling dizzy and that her throat was itchy. Vitals and assessment done by this RN; provider called in to room who evaluated further. 3:35pm VITALS/LUNGS/THROAT: 125/87 bp; 69 HR; 97% O2 room air; clear lung sounds bilat; throat check, no visible swelling. 3:50pm Pt reported feeling hot as well as throat slightly swelling. Denied dizziness. Vitals and assessment done by this RN; provider called in to room who evaluated further. 3:50pm VITALS/LUNGS/THROAT: 108/79 bp; 66 HR; 98% O2 room air; clear lung sounds bilat; throat check, no visible swelling. 4:04pm MEDICATION: This RN administered per verbal of BJB, Epi pen 0.3mg lot OFM128 exp 09/30/21 in to pt's right vastus lateralis. Pt tolerated well. 4:05pm VITALS/LUNGS/THROAT: 120/79 bp; 68 HR; 97% O2 room air; clear lung sounds bilat; no visible throat swelling. 4:15pm Pt reported lessened throat swelling sensation. 4:15pm VITALS: 116/77 bp; 78 HR; 97% O2 room air. Pt reported continued sensation of throat swelling sensation to provider. Pt refused EMS and agreed to further treatment of 2nd epi pen and famotidine IV. 4:25pm MEDICATION: This RN administered per verbal of BJB, 2nd Epi pen 0.3mg lot OFM128 exp 09/30/21 in to pt's left vastus lateralis. Pt noted site tenderness upon injection, otherwise tolerated well. 4:35pm MEDICATION: Pt began IV drip of famotidine 20mg/50ml over 15min through left arm. 4:40pm VITALS: 129/80 bp; 80 HR; 96% O2 room air. Pt's mother arrived to help pt home. 4:45pm VITALS: 126/78 bp; 83 HR. 4:50pm IV disconnected and pt was assisted with transferring to wheel chair. Discharge instructions for pt included provider recommending she go to ED for further evaluation. Pt refused. Provider sent pt home with #8 capsules of benadryl 25mg PO two Q4-6hrs; x2 epi pen pack of 0.3mg each, lot OFM128, exp 09/2021; provider also gave recommendation for pt to use triamcinalone pt already had on hand at home topically for red spots on anterior neck BID 7-10days and to avoid hot showers. This RN educated patient on epi pen administration, instructing her to try and do it while sitting due to affects on heart; to remove from plastic case, remove blue top, and to dart perpendicularly into outer middle thigh, hold for 3 seconds. Pt instructed to contact office for any questions and to seek emergency medical care for any worsening. Pt referred to allergist for consultation and approval for 2nd COVID-19 Moderna dose. Pt stated understanding.

Itchy scabs on left hand, both elbows erythematous, warm, itchy, indurated nodules. Also developed scabs/itching on backs of legs and toes.

My arm injection site was hurting. I had stabbing pains in my lower back like a knife into my spine. I had a fever, chills, dizziness, body aches, light headed. I could not hold my eyes open cause light was too bright. I had a migraine and nausea and vomiting. I had a knife stabbing sensation in my chest that did not stop. I was short of breathe and wheezing. Very itchy all over my body mainly on whole left side where I got the injection. Very tired and felt like I could not move

Pain, itching, redness, swelling started one week after receiving the vaccine. No other reactions prior. Got better with antibiotic and then worsened today (1/27/21). Redness spread and more pain and itching. Hot to touch. Will start taking a prescribed anti-inflammatory.

"Moderna COVID-19 Vaccine EUA" - large rash around the injection site approximately 6-7 inches in diameter. Rash has grown to this size within three days after second injection. Rash is red, hot, itchy, and sore.

I had a red raised hot area after the shot that itched. 10 days after I got the 1st dose, it spread throughout my arm. The small red, raised itchy spot had now increased in size and spread throughout my arm and up in my shoulder. My shoulder now hurts when I raise it up or try and pick anything up certain movements. My arm has a weird feeling in my shoulder all the way to my hand sometimes. It feels tingly at times but is not constant. My skin where the reaction happened is now different. It is rough and different to touch.

I was very sore at the site of injection around 6-7 PM. At approximately 1:00 AM, I started experiencing a fever (101.3 F), chills, aches, and some heart palpitations. I took 1000 mg of acetaminophen, which helped to reduce the fever and chills. When I woke up, I was nauseous, had a serious headache, fatigue, minor chills, a fever (101.3 F) and more noticeable heart palpitations (when measured with my smartwatch, it reported bpm of 118-124). I had a virtual consult with a physician who advised me to be seen by urgent care immediately.

Received vaccine at 9 am and was slightly fatigued throughout the day - mainly started around 1/2PM. Body aches and dizziness started around 6PM, aches ran from my lower back down to my toes. Headache (when standing), fever (between 99.8, up to 100.4) and chills started around 9/930PM. All symptoms lasted throughout the night. Body aches subsided around 10am. 1/29 - body is sore, pain at injection site, severe headache.

Swollen, red and firm at site of injection. Tender to touch. Developed low-grade fevers, body aches, as well as headaches in the evening and into the following day.

After the vaccine, I had the normal sore arm that went away after a day or so, but no real side effects. On day 8 after receiving the vaccine, my arm around the injection site swelled up around 3in wide and 4-5in long. It has been extremely itchy for a couple of days with the swollen area being very red.

about 30 hours after receiving the shot I got a rash on my stomach and feet. mild rash which I took Benadryl for. I have in the past gotten rashes when I have had an infection (UTI, etc.)

At 20 minutes s/p vaccination deltoid became extremely sore . At 2 hours s/p vaccination i became feverish. At 10 hours s/p vaccination I became nauseous and developed a severe headache.

Had muscle fatigue and chills with low grade fever for 6-7 hours. The injection site started swelling Saturday afternoon and increased in size and redness very fast. I applied an ice pack and took an Advil. Sunday the injection site is still swollen.

Patient developed a rash around the injection site immediately following the injection 1/5/2021. Patient was given Benadryl 25 mg po 1/6/2021 @ 0729 am, and rash subsided.

Headache, fever, nausea. Dizziness, sore at injection site, chills and sweats, body ache, trouble sleeping. Took Advil for the fever and headache - helped with fever but not the headache.

Started off as a hard, itchy patch on 2/20/21. Woke up 2/22/21 to it being three sizes of the initial reaction that was reported. Lethargy, muscle ache besides my usual rheumatoligcal issues, diarrhea, and lowgrade fever have been the reoccurring symptoms. Tried icing, did not make a difference

COVID Arm after second dose. Still experiencing rash like symptoms, itchiness, redness, swelling, burning, and hot to the touch. Headache continued from day 2.

Received vaccine at 12:10 pm on 3/15 1.) Noticed redness of bilateral legs around 2:10pm 3/15 2.) Woke up with epistaxis around 9:30am 3/16; rash on legs appearing petechial now 3.) Gums bleeding morning of 3/17, went to PCP, sent to ER, labs drawn -- > Platelet count of 1

1/25/21 - numbness and tingling, feeling of nerve tension began in right arm and hand with no clear peripheral nerve pattern; next day in both arms with twitching of R middle finger; third day afternoon began in R foot and spread up into calf as well as L foot; went to the ER on 1/27/21; clear ECG, chest XR, brain and cervical CT, and bloodwork; referred to neurologist with concerns of MS or transverse myelitis; saw neurologist on 2/3/21 - he found mildly hyperactive reflexes and a (+) hoffman's reflex; ordered MRI of brain and cervical spine with and without contrast and more bloodwork; MRIs performed apx 1 1/2 weeks later and bloodwork done same day (2/3); bloodwork revealed elevated C-reactive protein of ~14 and ESR of 14 (higher than previous baseline of <2) but all else clear; MRIs came back clear 2/8/21 - 9 days after second dose woke up with throbbing headache, body aches, and overall feeling of being ill; on the third day of this went to go get tested for COVID and flu to be safe; both rapid and PCR came back negative; sx resolved by the weekend; 2/15/21 - began getting frequent headaches, inability to take a deep breath and sharp retrosternal chest pain up into the back of my throat when I would try; difficulty breathing with a mask on; significantly elevated heart rate; SOB at work esp with mask on; symptoms worse with mask and then eased on weekends without mask; then became able to take deep breath but with chest pain then began to need to cough with a deep breath then more frequent coughing esp after long days of mask wearing; several occasions of waking up at night unable to breath esp when lying on either side with racing heart; symptoms vary in intensity but on days when they would act up, heart rate is consistently elevated (normal resting heart rate ~55, would be up at 90 while lying down, 120 while standing making coffee) 3/9/21 - went to ER in the evening due to symptom increase of chest pain, SOB, and elevated heart rate; ER ran bloodwork and found elevated D-dimer of 0.6, WBC of 27,000, high neutrophils, and low lymphocytes; CT angiogram to r/o PE came back negative; (-) chest XR other than minor atelectasis; abnormal ECG with incomplete RBBB and prolonged QT interval; tachycardia; admitted to hospital; blood cultures, urine cultures, and respiratory pathogen panel including COVID test negative; started on albuterol breathing treatments and 40 mg of steroids 2x/day which normalized WBC count and eased sx significantly; consult with pulmonology and cardiology; 2nd chest x-ray (-) and transthoracic ECHO (-); started on beta blockers 12.5 mg 2x/day which helped heart rate some; second ECG found no RBBB and normal QT interval but unable to rule out anterior MI or inferior ischemia. D/c on steroid dose pack, beta blockers, cough suppressant. Follow up with cardio and pulm. Now seeing immunologist as well who started me on corticosteroid inhaler, monteleukast. Running more blood work soon. PCP gave albuterol inhaler, did round of antibiotics, orders to use incentive spirometer for breathing capacity. Waiting on pulmonology follow up and 30 day holter monitor, stress ecg, and other cardiac tests.

Moderna COVID-19 Vaccine EUA Generalized external itching throughout entire body with no obvious rash involved. Symptom began approximately one day following vaccine administration and have continued until present day, so far now for 5 days. Have not taken any medications thus far but will try Benadryl today.

One week after my first dose of the Moderna COVID 19 vaccine (administered 12/24) I developed a large, itchy rash/hives at the injection site. The hives began 12/30 and are still present.

Swelling, hardness, warmth, and pain at injection site in left arm. Also major swelling and pain in lymph nodes on left side of body.

several white hives at injection site 7 days after receiving first dose. the hives went away after several hours (I took 25 mg Benadryl right away). There was a big red spot on my arm around the injection site for about 24 hours after the hives went away.

Large approximately 5 cm in diameter hive with redness and itching that showed up roughly a week after receiving the vaccine, at the injection site. It resolved after 2-3 days without any intervention.

24 hours after injection I developed a welt at the injection site that was raised, hot to the touch, sore, and about one and a half inches in diameter. The welt slowly disappeared within three days. Six days after the injection I tested Covid positive (transmitted from family most likely). The welt returned and began to itch and spread. Eight days after injection and two days after testing positive the welt was 5 inches in diameter. Nine days after injection and three days after testing positive the welt started to disappear again.

About 30 post administration, I had injection site soreness which progressively worsened in severity as time went on. About 12 hours after the injection I had a pretty sudden onset of fatigue, headache and nausea.

Developed a red rash around injection site. Mild redness for the first few days after administration which appeared to be resolving if not already resolved when it began to worsen about one week after administration. Now warm to touch, skin is tense and itchy.

Employee received COVID 19 vaccination at 9:45am on 12/30/20. ~15 min. later she developed a rash down her left arm, then down her Rt. arm. about 4 hours later she decided to go to the emergency room for Hearty Palpitations, Fever, Chest discomfort and feeling of generalized sunburn. Later developed severe headache..

I received the Moderna COVID-19 vaccine on Tuesday, December 29th at work and on Wednesday, December 30th when I woke up my entire neck had broken out in hives. I did not have hives anywhere else or any other reaction. After taking 25 mg of Benadryl po and applying hydrocortisone cream, the hives had cleared up about 75%. I continued to use the hydrocortisone cream throughout the day, but the hives/redness had fully cleared up by Saturday, January 2nd.

10 minutes post vaccination patient reported to clinic observation staff that she felt warm and flushed. Her face was red. We transported her to our on-site emergency room for evaluation.

Fever, body aches, chills, nausea, headache, soreness at injection site - all hindering normal daily activities such as performing work. This is day 8 of receiving vaccine.

Headache after shot was administered. At 0400 began having chills, body aches, redness and itching around injection site, nausea, sore throat, ear ache. Took Excedrin migraine. Symptoms have resolved.

Headache after vaccine administered. Around 0400 that morning complaints of chills, nausea, body aches, sore throat, ear ache, soreness and redness at injection site. Took Excedrin Migraine. Symptoms have resolved.

I had normal side effects at first. But this morning at work,(a week after vaccine), where I had the injection from the vaccine is red, swollen, and itchy. I spoke with my dr and he said it may be an allergic reaction to the vaccine and told me to report it here.

Joint pain/Muscle aches - 2 - 36 hours following shot Arm pain at sight - 1-48 hours following shot Headache - 2-24 hours Rash on back similar to shingles - 4-12 hours Chills - 12-24 hours following shot

Red Ring around injection, swollen, itchy, hot to touch, and wheezing. Patient took benadryl, iced and rested. Patient's PCP prescribed zpack and steroids.

itching, swelling, hives redness, blotchy skin lips & tongue tingling, scratchy throat. Began all upper body and spread to left leg.

PAIN AT INJECTION SITE X 2 DAYS FOLLOWING SHOT AND THEN I WOKE UP ON 12/31/20 WITH MY LEFT UPPER ARM SWOLLEN, RED, AND ITCHY FOR THREE DAYS. TODAY IS 01/06/20 AND REDNESS IS GONE BUT MY ARM IS STILL VERY ITCHY

Severe swelling at injection site. Nerve involvement - tingling and numbness in whole arm and extending up to neck. Pain scale 7-8 near injection site. Moderate headache and scratchy throat with mucus. Slowly getting worse (24 hours after injection).

WITHIN THE SAME DAY STARTED WITH RIGHT ARM SWELLING, REDNESS, WARMTH, AND ITCHING AT INJECTION SITE. TAKING IBUPROFEN AND ICED AREA. GOT BETTER AFTER A FEW DAYS AND STARTED BACK UP AGAIN, WORSE THAN BEFORE.

Woke up next day (12/30) with a hot red mark and bruising around injection site and soreness and pain. Later noticed lots of swelling in deltoid. Took the temperature of red spot that afternoon and it was 100.2 F. On 1/5 in the morning it appeared to be going away, but that night came back. 1/6 morning had soreness and now looks kind of like a bullseye

Adverse reaction 7 days after vaccine: 1" diameter hard lump at vaccine injection site, no itching, slight warmth to touch after I massaged shoulder. No adverse reactions up to this point beyond slight tenderness at injection site for the 24 hours after injection.

Delayed raised, red inflamed hive at injection site about 2 inches in diameter. Developed 8 days following injection.

Hives across chest and upper abdomen (developed around start of symptoms 1800-1830 1/5/21), dizziness, full body aches continuing 48 hours after vaccine received

I didn't have an adverse reaction until 6 days after the injection. The injection site became red and swollen and my whole body has been itching for 2 days now since 1/05/2021.

I received my vaccine in the left arm on January 4, 2021 around 2:20P.M. On January 6, 2021 around 4:30PM I noticed a rash that itched on my right arm. The rash consisted of small pimple like clusters along the length of my arm. On January 7, 2021 the same rash appeared on both my left and right arm and continued to itch. Prior to the rash there was some tenderness in the left arm at the injection site.

Localized rxn to injection site. Warm to touch, red area, itchy. Also reports throat swelling when received the vaccine but resolved with benedryl. No difficulty breathing.

Patient received vaccination yesterday morning. About an hour after receiving became shaky and felt flushed. States feeling did resolve after approximately 15 minutes. Woke up this morning with red bumps on the face that resembled small hives she has had in the past from allergens. Patient reports she did use a new facemask last night as well. Spots have gone down over the course of the morning. She used cold towel and topical benadryl and that has helped a little bit. Patient appears well and in good overall health no fever nausea or vomiting. Pt has no further concerns at this time.

Presented to Urgent Care 01/05/2021 Pt. States swelling started the night prior. Provider describes it as left upper arm finds a patch about the size of a silver dollar which is red, warm, + tender with some indentation in the center. No red streaking up the arm, shoulder

Reports symptoms started 1/7/21 7 AM with pounding headache, nausea, rapid heart rate. Had chills that shook her in night. Went to work. HR has been 100 since awakening. Injection site is red and inflamed. B/P 142/100. Instructed to go to urgent care. Urgent care sent her to Emergency Dept. Per Dr., ED provider, he wanted VAERS completed. Patient has tachycardia 140-150. No rash or swelling. Has body aches and Headache. Temp is 100.3. Undecided if will be admit to hospital at this time.

Stomach pain to the point of vomit, extreme nausea, lasting for over a week and a half, dizziness, swollen arm, itchy arm up to 10 days latter.

Arm soreness at injection site began a few hours after injection. About 18 hours after vaccine was given, experienced body aches, and tingling/numbness in arm that had injection and legs. Around this time also felt a little dizzy/light-headed.

Employee here with COVID vaccine reaction was given shot in right upper arm in deltoid area on 12/30/20. Redness came on after the vaccination but went away then on 01/07/21 it came back. The site is red, swollen, warm to the touch, with clearly defined borders. Site is 3.5 X 2.5cm and outlined in ink for monitoring. Explained conservative measures including cool compresses, if allowed by PCP taking OTC IBU and OTC antihistamines. If area worsens skin becomes taught or streaking develops to seek further care form PCP or walk in clinic. Employee verbalizes understanding and agrees with plan.

Initially had (unconcerning) soreness/pain at the injection site hours 6 through ~60 after the vaccination. Soreness completely resolved after hour 60 then on day 7 post vaccination my arm began to feel tender again. Day 8 post vaccination it is painful at the injection site and the pain is only moderate but somewhat limiting. I have no other sx and did not injure or over-use my muscle. I don?t intend to take any medication for the discomfort. There is no redness/swelling at the site, just pain like there was immediately following the vaccine. I stopped getting VSAFE check ins after my third day of no symptoms which is why i?m completing this form.

Left arm injection site was swollen and sore first 1-3 days after injection. Soreness has dissipated, but injection site remains somewhat elevated. Red rash at injection site after showering. Injection site itches, especially when rubbed. Uncomfortable pinching sensation in left armpit starting approx. 1 week after injection through today.

Mild congestion starting the night of injection The day after injection I experienced a low grade fever, chills, extreme muscle soreness, headache, and soreness at the injection site. These symptoms lasted approx. 24 hours and then subsided.

Moderna COVID?19 Vaccine EUA. States she experienced fatigue 24 hours after and immediately felt like she had swelling/lump under her skin. States last night she started with itchiness over the injection site. Today she has developed warmth and redness. She denies discharge, fevers, shortness of breath, cough, wheezing, swelling of mouth or throat, n/v, or rash elsewhere. She denies receiving any other vaccines in that arm since then or injury to that arm. She reports the nurse did clean her arm with alcohol swab prior to vaccination and a bandage was placed. She did report her symptoms to employee health and was told to be seen.

Nausea. Vomiting. Migraine. Hot, but had constant cold chills Body aches, head to toe. Extremely tired. Super sore on injection site and about 4 inches surrounding.

On Wednesday January 6th, I started to have itching, swelling, and redness at the injection site. The injection site continued to swell and was warm/hard to the touch, with mild pain. I took Benadryl that night (Jan 6th). On the morning of January 7th, the swelling had gone down but redness and warmth at injection site was still present. I took Benadryl that night (Jan 7th) as well. Today, January 8th, the redness and warmth is still present.

She reports waiting the allotted time of 15 minutes after receiving the Covid injection. She reports after the 15 mins. that she returned to her work area where co-workers commented that she had a red blotchy hive looking rash around her neck and upper trunk area. She denied any itching or SOB and reports that the blotches were noted for approx. 3 hours after shot. She was instructed prior to 2nd Covid shot to contact PCP with understanding voiced.

Vaccine received 12/31. Arm pain persisted x3 days. On 01/07 large itchy welts broke out on injection site. over time welts went away and whole area became red, swollen, and hot to touch. Arm also became sore again. Cortisone applied twice with minimal relief.

10 minutes after getting shot, my lips started swelling and tingling and itching. Hives/ Redness on my face 30 minutes after- throat started itching Treatment- given Benadryl, Pepcid, Steroid in Emergency Room and was observed from 10:30ish until 2:15p

Headache Fever Chills Body aches Nausea Diarrhea Joint pain Reddness and swelling to injection site Cold sweats

I received my vaccine in my right arm around 3:20 pm on 1/5/21. My right arm started getting sore later that evening. The following day, 1/6/21, my arm was very sore and the injection site was tender to touch. I felt feverish and had chills. I also had a headache and felt very fatigued. I took some Advil that morning. I evaluated my arm in the evening and noticed a large red rash streaking down my right arm from the injection site. It measured approximately 3.5 in X 1.5 in. The rash was red, raised, painful, and firmer than my surrounding skin. I took 500 mg of Tylenol before bed. The next morning, 1/7/21, the rash had grown larger. The border of the rash was marked and I took an antihistamine around 7:00 am. At 1:00 pm the rash had grown larger, now measuring approximately 4.25 in X 2.25 in. My lymph nodes in my right armpit were also beginning to get sore. I visited the nurse practitioner at my hospital?s employee health clinic around 1:40 pm and we agreed to monitor my signs and symptoms at that time. The following morning, 1/8/21, the rash was bigger, but my skin was softer and more of a pink color than red. My arm did not hurt as much, though my right armpit was slightly more sore. Today, 1/9/21, my symptoms are much better. I have only slight soreness in my right arm and armpit. My rash has nearly resolved, though it is slightly itchy where the rash was.

No symptoms until 1/7/21 when my arm was itchy, pink, and raised. It was same temperature as my arm, but it was approximately 3 inches wide and 2 inches long, and pretty much an oval where I had the vaccination.

10 days later, developed a 3? round circle directly around injection site. The circle is red, raised, hot to the touch and has not gone away. I also am experiencing some itchy ness on the right arm radiating to my chest and back. My back has also developed a minor rash with itchy ness

Day 1 of injection regular arm soreness Day 5 axillary soreness and tenderness Day 8 raised and red rash on injection arm but below the injection site.

9 days after I was vaccinated, I noticed a large red area on my left arm at the exact location of the vaccine. The rash is about 2.5 inches long and 2 inches wide. I first noticed it around 7:30 am today (1/11/2021) and it is now 6:23 pm. It doesn't appear to have grown but it has not gotten any better. The rash is red and raised and warm.

Approximately 7 days post vaccine administration, a welt the size of a palm (like a giant singular hive) with a 1-inch red circle around it appeared at the site of vaccination. Localized numbness, swelling, redness, heat, soreness present. I drew a circle around the redness & the welt. Within 12 hours, the welt had dissipated, but the redness had grown outside the outline. Swelling decreased, but site was firm, hot, red, and more sore.

Day 1 Hot welt developed on arm. (Area grew to size of baseball over the course of three days) Day 2 Unable to move right arm above shoulder. Day 3 Radiating joint pain running from right arm down spine. Extreme fatigue. Headache. Day 4 Hot welt continues. Headache. Day 5 Hot welt subsided, lump left under skin with gray/blue discoloration. Day 6 Still feeling joint point throughout body.

Moderna COVID-19 Vaccine EUA Extreme Swelling of site area - softball size Site area Hot to the touch Fever of 101.7 Dizziness.

No adverse event until Day 9 post-vaccination, when patient reported the appearance of a flat, pink-reddish rash 1" in diameter with an irregular border surrounding the injection site (L deltoid). Patient reports that the area grew to about 4-5" in diameter over the course of the next 7 days, some swelling noted, and that the top area of the rash had faded while the bottom area was travelling down her arm. Reports the affected area feeling warm and tender upon touch. Denies pruritis, fever, axillary swelling, or any systemic reactions. Denies any unusual pain.

Red, itchy rash, hot to touch, appeared around injection site, around 3 inches in diameter, 12 days after receiving injection. Rash increased in size the following day but had less clearly defined borders. Rash began to resolve within 24 hours after taking antihistamine.

Red, itchy, raised skin at injection site. Began 7 days after 1st dose, still itchy (not worse) 9 days later.

Red, raised, itching area measuring 3x3in at injection site. Full body itching. Lasted for 12 hours. Used hydrocortisone cream and Zyrtec.

Small rash slightly behind left armpit in the same arm vaccine was administered. The rash lasted about 3 days and is now gone. No other symptoms other than arm pain at injection sight which lasted about 5 days.

Sore, tender arm for approximately 48 hours. Local bruising for about 3-4 days. Chills after 24 hours, body ache, redness.

soreness, fatigue chills : Day 1 Itching : Day 5 Rash with numbness, swelling : Day 7 Above all recovered Light headed : Day 8th to now

Arm pain at site lasting more than 24 hours. Radiating arm and neck pain and stiffness for first day, eased with sleep overnight. Feverish and chills in the evening of first night, eased with sleep overnight.

Around 1/10/21, site of injection started inching and was red. On 1/11/21, about a 2 inch redness around injection site, no itch. On 1/12/21, 2 inch redness remains, but the inside of the red area is my skin color, no itch.

Building pain throughout the evening in the arm of the injection site starting mildly around 5pm and increasing through the evening. Mild swelling of the arm around the injection site by 6pm. Chills developed around 6pm, no obvious fever. Aparent moderate fever with moderate chills developed around 9pm. Fever spiked around 10pm, chills continued. Consumed 2 benadryl tablets to assist with sleep. Fever, chills, and swelling were gone at time of waking up around 10am. Arm pain continued for 1 and 1/2 more days.

Day 1 after injection: slight redness and moderate pain. Both went away within 3 days. Day 7 after injection: increase redness, swelling, temperature, and itchiness at injection site. Continuing to last until today.

Day 8 after being vaccinated with the Moderna COVID-19 Vaccine EUA my arm became red, hot and swollen. My arm was also sore. the area affected was right under the injection site.

Moderna COVID-19 Vaccine Exactly seven days after receiving the first dose of the vaccine I developed a rash that reserved a large hive near the site of injection. The skin was red with a wheal-like appearance and felt warm to the touch as well as swollen. I had no other symptoms and it was mildly itchy but not very bothersome. This rash improved by the next day, however the area was still red (less swelling and less redness overall) and now it is only very faintly noticeable.

Non-anaphylactic reaction. Patient began to experience tingling/numbness on her fingers and Itching on chest area. Patient was given 4 ml of Benadryl at 6:15 patient was discharged home at 6:35 with improving signs and symptoms.

On January 7 (approximately 1 week after getting the first dose of the Moderna vaccine), I experienced itching, hives, redness, and swelling at the injection site. None of these symptoms appeared immediately after getting the injection, and only first appeared on January 7. The symptoms subsided after 3 days and multiple doses of benadryl.

Redness and swelling of cheeks. Face feeling hot to the touch. Redness of neck. Took benedryl, ibuprofen and omeprazole and symptoms went away in a few hours.

Beginning 1/12/21, site of injection was itching. Upon touch, there is a lump that is raised and bigger than a quarter. Additionally, there is redness on the site of the lump. A sore arm began to return again and the site is warm to the touch.

On Friday 1/8/21 0830 Patient started to have whole body aches and soreness to the arm where vaccine was given. Patient developed a fever of 102.0 at 1pm then took Ibuprofen 800mg and took temperature again and it was 99.4. Patient also stated she was tired. Patient was advised to push fluids and take Tylenol 1G now . Body aches and fever went away on 1/9/21. Patient stated she was tired and had a HA until 1/11/21.Patient took Tylenol to help with these symptoms which was effective.

Patient developed rash at the injection site 7 days after injection. Patient has no symptoms just the late onset rash

Patient noticed redness and itching at injection site. Her arm was very painful and warm. Felt a pop in her arm near injection site and experienced sharper pain. Rash gradually over the next couple hours spread from her arm to her upper chest area.

Patient reported itching at injection site immediately after vaccine given. States it decreased while she was in the observation period. She states it has not resolved; she did have a bruise. Patient reported itching at injection site immediately after vaccine given. States it decreased while she was in the observation period. She states it has not resolved; she did have a bruise. She was not given any BENADRYL at the clinic and did not take anything for symptoms at home. Resolved by 2 days after injection. She denies: Feeling of impending doom, Skin symptoms present in 90% of people with anaphylaxis, including pruritus, flushing, angioedema, Confusion, disorientation, dizziness, lightheadedness, weakness, loss of consciousness, Shortness of breath, wheezing, bronchospasm, stridor, hypoxia, Hypotension, tachycardia, Nausea, vomiting, abdominal cramps, diarrhea.

Starting 24 hours after injection, employee started to develop a red, hot, tender patch of induration around the injection site. This steadily increased in size and severity over days 2 and 3 post injection. The reaction finally resolved 14 days after injection.

Starting on 1/12/21 about 24 hours after vaccination, I felt very severe flu-like symptoms. I had nausea, chills, felt very lethargic and sore to the point where I couldn't stand at work, and had a pounding headache. The site where I got the vaccine was also more tender and sore than usual after a vaccination. I left work early around 3 pm, took 400 mg of ibuprofen every 6 hours and tried to get as much sleep as I could. By 6 am on 1/13/21, all these symptoms had gone away, but now I've noticed a very swollen lymph node just above my left clavicle.

patient go her first dose of vaccine on 12/29. on 1/11 her arm started itching and now have a wheal at the vaccine site. Rash lasted 2 and half days and now resolved

swelling and redness at injection site day after shot - used over the counter Benadryl. Swelling/redness went down completely by Sunday (1/10) Saturday 1/9 - 2 days after vaccine experienced extreme fatigue, slight head ache and body aches. Used Advil for these symptoms. Sunday 1/10 - still felt slight fatigue and headache. Used Advil and also drank emergen-C packet. By mid day felt much better with nearly no symptoms.

12/23/2020: 2 hr after injection, patient noted swollen lymph nodes, nausea, room spinning (motion sickness-like) sx. Stayed home from work that day and slept. 12/24/2020: "typical injection site pain" 12/30/2020: injection site hot, itchy, welts 12/31/2020: area of welts doubled in size to entire upper left arm; throat starting to close up

7 days after initial IM injection--pain, pruritus, redness and warmth of left deltoid. Area felt indurated on palpation. Resolved after 2 days. Highly localized to injection site.

Heat, bruise like patch (possible rash) below injection site, edema around injection site. Personally feel it is localized cellulitis.

Injection site reaction to left shoulder with swelling, redness and warmth to touch after the 8th day of administration of Moderna Covid-19 Vaccine.

My arm was sore and tender for the first day after receiving my first dose of the vaccine, which was expected. There was no redness at the time and no other symptoms. About 7 or 8 days after receiving the first dose, the area around the injection site became red and warm and the redness continued to spread over the next day. I will be trying an antihistamine to see if this resolves the redness/warmness, and will see a doctor if it does not resolve over the next day or two. Otherwise, I have no other symptoms and feel fine.

My arm was sore and tender for the first day after receiving the first dose of the vaccine. I had no other symptoms at the time. About 7 to 8 days after the first dose of the vaccine, my arm became red and warm at the injection site, and the redness continued to spread over the next day or two. I still have no other symptoms and feel fine overall. I will try an antihistamine to see if that resolves the redness and will see a physician if no improvement in a day or two.

ONE DAY AFTER 1/9/21 VACCINE DOSE, DEVELOPED ARTHRITIS AND ARTHRALGIA OF MP JOIN- IMPROVFED 1/13/21 2-3 DAYS AFTER VACCINE DEVELOPED A TRUNCAL ERYTHEMATOUD MACULAR RASH, NOT PRURITIC, IN TRUNK ARMS AND FACE. AS OF 1/4/21 RASH PERISTS FATIGUE SINCE VACCINE BENADRYL NOT HELPFUL

Pt. received vaccine at 1520. At 1530 pt. started with itching, burning pain and patchy erythema without urticaria. No dyspnea, angioemdema or wheezing. Pt. also experienced mild anxiety with O2 sat at 99, pulse 90 and BP 120/84. At 1535 50 mg diphenhydramine given IM in R deltoid and ice pack applied to L shoulder. At 1550 pulse 90, O2 sat 99%, BP 130/90, respirations unlabored and pt. reported mild dizziness, but not feeling like fainting. At 1615 itching reduced, pt.'s primary care provider, contacted and situation was reported to triage nurse and on-call provider. Provider advised pt. okay to go home if responding to the diphenhydramine.

Received the vaccine at 1600 on 13 Jan 2021. At approximately 0700 on 14 Jan 2021, I noticed redness and swelling directly below injection site. It was tender to the touch but painless otherwise. At approximately 1400, the swelling began to burn without touching, causing discomfort and pain. Moving my arm causes pain at swollen area.

Right sided facial rash and itching and bilateral eye swelling developed 1 hour vaccine administration. Treated with Benadryl, Naproxen and Claritin. Itching resolved on 1/11/2021 and eye swelling and rash resolved on 1/12/2021

Swelling in arm just below and to the right of injection site. Swelling is very red/warm to the touch. The area has remained the same since 1/7/21 and has not increased or decreased in size. However the itch/burn feeling continues to increase daily. I do not plan to seek medical attention for this side effect unless the swelling is still present by dose #2. Im showing no other negative symptoms.

At 9:00 PM yesterday I had full body chills, body aches, and nausea. At 11:00 PM a fever of 100.4. About 20 minutes later my fever went up to 101.6. At this time I took Tylenol. With the fever came a head ache. My injection sight is very painful. I did not sleep very well. When I woke up at 7:00AM my fever was 100 degrees. It has stayed at 100 degrees until this point (1:30 PM). My headache became painful enough that I took 2 excedrin that have relieved most of the headache. My symptoms are improving as the day progresses. My injection site is still very painful. With the normal flu vaccine I get yearly I have never had any problems.

I waited 20 minutes after my injection and left facility. While I was driving home around 1:00 pm my left arm started to tingle, I got really hot and a wave of lightheaded/dizziness washed over me and I couldn?t swallow. I pulled over to wait it out and my throat swelling got worse.

Moderna COVID-19 Vaccine EUA. Dark red rash on inner part of upper right arm. Not hot and does not itch.

Moderna COVID-19 Vaccine EUA: allergic reaction at site of injection (upper left arm red and swollen)

Morning after injection experienced exceptional fatigue, relief from fatigue by Sunday morning. The following two days after injection experienced redness around injection site.

New onset of redness and warmth of LUE, denies pain. Skin with blanching, erythematous, edematous. Diagnosed with cellulitis and treated with antibiotics.

Patient experienced tightness to the left arm, felt the need to take deeper breaths, chest heaviness, nasal stuffiness, bilateral hands tight and swollen, redness/blotchiness to bilateral upper extremities, itchy skin, nausea.

Patient reported localized hives and itching to the left arm about 30 minutes after receiving vaccine. Paramedic on-duty immediatley brought equipment to patient to render care. Patient was given 50mg of benadryl IM and monitored for an additional twenty minutes. Patient's symptoms resolved and she expressed that she did not feel ambulance transport to hospital was necessary. Paramedic obtained an Against Medical Advice from medical control and patient was released into her mother's care with advice to activate 911 should symptoms return.

Patient reports, "Received COVID-19 Moderna Vaccine yesterday in my right arm. About 10 minutes after the shot my arm became hot, then numb, and my fingers went cold. Eventually the whole arm numbness resided and only from my elbow up was still numb. However, the numbness radiated to the front of my right chest and back of my right shoulder. I called the Associate health number as instructed by the pharmacy team who then told me to go to the ER for further evaluation. "

Pregnant EDD is 7/20/2021 First pregnancy Adverse reaction was bilateral hives starting in both hands and spreading to armpits. Treated with hydrocortisone and Benadryl x 3 days resolved.

Rash both arms day of injection and still present when seen 1/11/21 with additional rash noted on legs. Also bruising on legs (?timing).

Red swollen, sore for 2-3 days after injection on 12/29/2020 1/6/2021 and 1/7/2021 became swollen, itchy, warm, not painful (took ibuprofen) 1/8/2021 continued to be slightly red

She received the Moderna COVID vaccine on 12/22/2020. She had no initial problems with the vaccine. Had a little soreness in the arm of the injection, but otherwise fine. Today, she has noticed itching and redness around the injection site. Located on the left shoulder.

12/29/2020- Received the Moderna Vaccine - no pain or problems until 01/04/2021 01/04/2021- Before bedtime my injection site from the Moderna Vaccine became itchy. 01/05/2020- Woke up to a swollen arm (about 3 times the size of my right arm) and the start of a rash (the size of a softball) Was in significant pain and unable to lift my arm. I called the nurse hotline where I received the vaccine. I was told to go to the ER immediately. The ER doctor informed me that they had been seeing this and that their personal vaccine location swelled up as well but went away a few days later. ER doctor gave me Benadryl cream (I can not ingest Benadryl due to an opposite reaction, I become extremely anxious.) The ER doctor informed me that the Benadryl cream wouldn't cause the same reaction. I was sent home with the cream and a wrap. Upon arriving home my rash grew exponentially over the following days. The site became hot (even after icing it) It remained itchy and painful. 01/11/2021- Went to primary care doctor. The rash and swelling had decreased although you could still see the ring of the rash. At this point, my hand was becoming numb after doing daily activities including typing. My palm and thumb area started to turn purplish/blueish when I would type for less than 20 seconds. The doctor told me they would start to reach out to other providers and figure out how to best move forward. In the meantime, there wasn't much to do besides wait and see what happens. 01/13/2021- Woke up throughout the night due to continued pain at the injection site. Called the primary care doctor who wasn't in the office, waited for a call back from their nurse but due delayed call back and increased pain and numbness went to urgent care (which is under the same practice as primary care). The urgent care doctor performed tests regarding pinched nerve shoulder (as they believed I had a pinched nerve in my shoulder) and ordered an x-ray. The x-ray showed tissue damage but nothing else. I was not experiencing shoulder pain, although during one of the shoulder tests I found more discomfort in my left should (injection arm) than my right arm. Therefore, the primary care doctor thought I was experiencing a pinched nerve in my shoulder. 01/14/2021 - Primary care doctor called and informed me they had spoken with the infectious disease doctor in the area who informed them that they have been seeing a similar reaction amongst other people. (7 days after inject, swelling and rash) The infectious disease doctor reported they hadn't seen numbness. The primary care doctor advised me to wait 2 weeks to see how symptoms change before performing additional tests. The primary care doctor also advised me after speaking with the infectious disease doctor to not take the second shot. 01/16/2021- still experiencing issues with daily functioning. Still experiencing numbness in hand and arm. Still experiencing redness around the injection site (although much better still flairs up at moments) Side note: 01/03/2021 - Went cross country skiing, did fall backwards but did NOT fall on arm. Also confusion remains if I was supposed to report this or if the primary care doctor/ER doctor reported this, therefore, urgent care doctor told me to report this reaction.

At the time of injection, the site became swollen and tender, and was red, itchy, and warm to the touch. I knew this was a normal side effect so I was not worried. They faded after a couple of days. However, a week after the injection, these side effects returned. My arm was not as tender but it is itchy, red, warm, and swollen (feels firm.) I doubt it is anything serious but I figured I should report it just in case.

Felt pain at left ( injected side) axilla and breast in the morning on Jan 13 and then had pain, swelling, warm, itchy at left arm in the evening at the same day. Symptoms become better without taking any other treatment since Jan 15.

Patient developed severe itching and subsequent rash of right upper arm and injection site 1 week post injection. She also is experiencing malaise, muscle pain and fatigue.

Tenderness, swelling and redness started on 1/14/21 and has been present since then until today 1/16/21. My arm was looking better yesterday the redness was going away but was still more swollen and tender. It is hot to the touch and today 1/16/21 the redness increased and expanded.

-Extreme fatigue, malaise, muscle and joint aches, injection site pain (lasted 48 hours -chills, nausea, vomiting every 30min (lasted 6 hours) -4 inch raised welt at injection site appeared several days after injection and lasted about 48 hours Was unable to work for two days after receiving vaccine

1/16/2021: slight headache, 99.7F fever, pain (at site of injection) 1/17/2021: slight headache, 100-102F fever, drowsy, pain at site of injection)

Swelling in left armpit 3-7 days after. Swollen left neck. On the eight day woke up with injection site red. Soon after had rash on neck and chest. Then developed facial itching with facial swelling and eye swelling. Resolved with Benadryl. Lymph nodes still swollen.

After the injection, I did not notice any signs or symptoms. Around 10:30-11 PM I noticed I was starting to feel itchy. I did not think anything of it and continued to lay in bed scratching. When I got up an hour later to use the restroom, I noticed hives all over my forearm, on my leg, and sides. I did not notice anything concerning with the injection site. I did not have any trouble breathing, I just took a Benadryl. The morning of 1/20 around 8:30 AM I noticed I am starting to feel slightly itchy again. My arm (injection site) is red and very painful.

Days 1-5: R arm pain, tenderness & soreness, stiff neck, headache, myalgia, body aches, chills, fatigue Days 5-6: nausea, diarrhea, abdominal pain/cramping, chills, fatigue, headache Day 7: itching at site followed by sudden acute onset at injection site of hives, swelling/redness greater than the size of a fist, hot to touch, painful which spread to 1/4 of R arm

Eight days following vaccine, large localized cellulitis type reaction. Gradually increased in size of 2 in diameter to 6.5 in diameter over 72 hours. Painful, red, hot to touch, and hard. Keflex and steroids given which subsided pain and hardness. Still red and warm to touch on day 15.

Hives and itchiness at injection site 8 days after initial immunization. Redness with splotchy appearance and slight irritation remained for 7 days after initial hives.

Hives at injection site 8 days after vaccine was administered. Redness and slight irritation remained at site for an additional week before clearing up.

Pain in injection site for three days - pain has decreased over the three day period Fatigue and body aches day after injection Headaches for three days after injection. Mostly dull but consistent headaches those days except for the second evening after injection was sever headache on left side of head that felt like a migraine- I do not usually get headaches and never a migraine

Patient reports numbness & tingling with a heavy arm 10 minutes post vaccination. V/S taken WNL. BP-126/92, HR 80, SPO2 98%, RR-18. Patient given electrolytes for rehydration. Patient reports suffering from medical PTSD of 15 years ago. Pt observed for additional 15 minutes. Pt discharged at 1705. BP 126/92 HR 80 O2 Sat -98% Pt reports tingling & numb in (R) fingertips, arms heavy 5lb.

Soreness in lymph node in armpit on side where shot was given, began on 1/17/21, continued to 1/20/21. Swelling and hive like rash on site of injection (size of a quarter), appeared on 1/20/21. Claritin taken in response to hives.

injection site itchiness, persistent at least a week after injection. 12 days after shot, noticed red raised skin around the area of injection (like hives), and skin temperature of the area was significantly warmer than the rest of skin. Other than arm soreness the day after injeciton, no other side effects noticed.

muscle pain from injection site has remained but improved from the day before, slight headache which improved after sleep, severe chills - multiple blankets used including heating blanket used which improved after sleep

12/24 Vaccination Thursday after, 12/30th, I woke up. Felt arm was itchy. Large, oval shaped, size of a baseball red mark. Slightly raised, warm, very itchy. The redness spread when itching, spread with welts on upper torso. Lasted for 4days. I tried anticortisone cream but didn't help.

About two inches below the injection site started itching a week after administration of the first dose. Throughout the day a red, slightly raised area appeared around the site that has been growing in size and is warm to the touch.

Large raised red circle in area of injection site, as well as smaller rash/hive marks appearing on other limbs, that appeared 9 days after injection. Also consistent nausea, and severe headache that covers whole right side of head, as well as severe pressure behind right eye. Also sudden fatigue and muscle aches. Red circle is warm and painful to touch.

One week after administration, developed area locally at injection site of redness, induration, itching and mild swelling. Also felt itching over rest of body but never developed rash. Lasted about 48 hours then disappeared.

Patient received the vaccine on 1/7/21 Developed a 6 inch long in width and diameter rash around the injection site on 1/21/21 that is now hot to touch

Rash on injection sight of injection 8 days after the shot. Red spots on hands and feet. Itching on all of these sights.

Red swollen circle about 2 inches diameter. Area is hot to touch and very itchy. Has become increasingly red, larger area, and itchier over the past 8 hours.

Starting the evening of the day I took the vaccine, I developed arthritic pains in my knees and hips. This pain has since became fairly severe - making it hard to go up and down stairs and even roll over in bed - involving knees, ankles, hips, wrists, and shoulders now. The only thing that helps the arthralgias is ibuprofen - it makes my symptoms resolve probably 75% of the way but they return as soon as the 8hrs is up on the ibuprofen. Three days after the vaccine (the 13th), I developed an erythematous macular rash on bilateral thighs. It has since moved to my lower legs and there are a few spots on my forearms. The older macules on my thighs are now a purple-ish hue, but the lower leg ones are very much erythematous and warm. I have also been have intermittent lower extremity edema for the last week. Tylenol, benadryl, and zyrtec did not help any symptoms.

Swollen and warm bump at injection side that developed into a large bright red, tender rash all over my deltoid

burning, painful blotchy hands, sweating. Rash escalated to face, sweating, 10/10 pain all over body, shallow breathing. itchy tongue. fevers

c/o headache, pressure in her head, c/o pain in arm at injection. Physician assessed patient and d/c back to work in stable condition.

patient reports left arm itching/rash/raised area at injection site. Patient reports axillary lymph nodes swollen that started at 6am this morning 1/21/2021

-Feeling hot then cold with chills related to fever of peak at 102.7 - treated with Tylenol 650mg q6h. 3 days later my temp is 100.4 Fahrenheit -Body aches all over -migraine off and on - treated with excedrin migraine but migraine still present, -Arm pit lymph nodes swollen in injection arm - using warm compresses -injection site pain 6/10 - can?t raise my arm more than halfway -my lungs feel sore - hurts to breathe -sore throat -extreme fatigue - exhaustion walking 10 feet to the bathroom

Slight swelling on left arm under the spot given shot, slight redness and itchiness to the next day, some chills and goosebumps.

5 minutes after vaccine, patient experienced flushing of chest, neck and face followed by urticaria. Tachycardia and hypertension with feeling of impending doom. Responded to Benadryl 50mg IV, Famotidine 20mg IV and Solumderol 40mg IV. Symptoms lasted approximately 1 hour after they started. Rx for prednisone taper and famotidine to continue for next week as well as OTC Zyrtec 20mg BID.

delayed rash at injection site about a week later (non painful but growing in size); migraine/tiredness/arm soreness day after vaccine

employee reports receipt of COVID-19 vaccine dose #2 on Thursday 1/21/21. C/o left thigh problem. Reports the following day post vaccination (Friday) had injection site pain, eyes were burning at work and general malaise. Reports she took tylenol and went home early due to symptoms. Reports fever up to 106.6 F Friday night which resolved the following morning. Now concerned about left thigh problem. States she woke up Saturday morning and when got out of bed left thigh was "off". States feeling like she is not able to walk normal since then, feels like she's "limping". Denies any falls. Patient also concerned about late menses. States she was scheduled to get it on 1/20/21 and wonders if this is vaccine related.

Began developing a rash about 4 inches in length, 2 inches across at the injection site of the vaccine. This occurred 10 days after receiving vaccine. The rash is hot to the touch, slightly itchy, and skin underneath is a bit hard.

Hives that started 2d after vaccine, tongue swelling 4d later and redness and swelling at injection site. Discussed with Allergy-do not take Moderna 2nd vaccine.

Received Moderna Covid 19 vaccine on 1/16/21 still warm to touch, red and swollen. She thinks the swelling and the pain, warmth has stayed about the same since last weekend, no better or worse. denies muscle pain, fatigue, fevers, or chills. left deltoid has a circular 1.5in x 1.5in area of erythema, induration, pain to the touch. It is quite warm on palpation. This looks and feels the be cellulitis, although its not progressing. It very well could be still be caused by the immunogenicity from the vaccine, but we will treat this as a cellulitis. Call if any worsening please - cephalexin (KEFLEX) 500 MG capsule; Take 1 capsule (500 mg total) by mouth 2 times daily for 7 days Dispense: 14 capsule; Refill: 0

7 days post vaccine dose #1 - armpit pain on side of injection and small rash and swelling at injection site

Cellulitis at middle arm and not on deltoid; Redness which is 3in in size; Itching; Hives; A spontaneous report was received from a nurse concerning a 27-year old, female patient who received Moderna's COVID-19 vaccine and experienced cellulitis at middle arm and not on deltoid, redness which is 3in in size, itching, and hives. The patient's medical history was not provided. Concomitant product use was not provided by the reporter. On 30 Dec 2020, the patient received their first of two planned doses of mRNA-1273 (Lot number: 025J20-2A) for prophylaxis of COVID-19 infection. On 09 Jan 2021, the patient experienced redness which is 3in in size, itching, and what the patient described as hives. The patient went to urgent care where she was diagnosed with cellulitis at middle arm and not on deltoid. Treatment for the events included antibiotic and loratadine. Action taken with mRNA-1273 in response to the events was unknown. The events cellulitis at middle arm and not on deltoid, redness which is 3in in size, itching, and hives were considered not recovered/not resolved.; Reporter's Comments: This case concerns a 27 year old, female patient, who experienced a serious unexpected event of cellulitis; non-serious unexpected event of pruritus and urticaria and a non-serious expected event of erythema. The event of cellulitis, erythema, pruritus, and urticaria occurred 11 days after first dose mRNA-1273 (Lot# 025J20-2A) administration. The treatment medications included Claritin and antibiotics. Based on the current available information and temporal association between the use of the product and the start date of the event, a causal relationship cannot be excluded.

I now have a red and itchy rash with a lump by the injection site it?s 8 days since I received the first shot of the moderna vaccine

I received the vaccine on 1/19 and it is not 1/26. I had no severe side effects except for minor headache and soreness in the arm. However yester day I noticed the injection site had become red and raised. It is a bit hard and very warm. When I woke up today it was even bigger, about the size of a quarter.

On January 16, 2021 I started to have axillary swelling and tenderness. Now on January 27, 2021, that discomfort and tenderness is still present. I have also had a large raised, red, hot, itchy local reaction at the vaccination site that has come and gone throughout these past two weeks. Today it is at its worst.

Patient experienced flushing/redness throughout her body. Appeared to be early allergic reaction. Was given PO Benadryl and monitored for 30 minutes. s/s resolved and patient left facility in no distress.

Patient had COVID vaccine on 12/28. Mild symptoms day after with site tenderness all of which resolved. Then woke up on 1/5 with baseball size reddened area with hardened center at injection site. Patient seen at urgent care and was put on doxy for ? cellulitis. Patient to report to V-safe.

I received the second Moderna dose on 1/26/2021 at 10:10AM. No immediate reactions after the injection. At approximately, 4:47PM I noticed a small red swelling at the injection site. I took a tylenol 500MG extra strength . By 5:53PM the swelling slightly increased to the size of a dime. On 1/27/2021, at 7:43AM the swelling and redness had dramatically increased larger than the size of a quarter . By 3:49PM the swelling and redness continued to increase and get bigger to about an inch. At this point, I consulted with a doctor who advised a cream and allergy medicine. It is 10:55PM and the swelling and redness have increased in size even more and it looks like a large rash. There was no itching or red lines streaming down. The shape of the rash is a circle with dark lines and bumps on the edges.

My arm is very sore at the injection site to the point where I am having trouble lifting it or applying pressure on it. I also had a very mild headache shortly after receiving the shot. This has come and gone within the last 12-15hours (since I received the shot). I also started experiencing mild chills at about hour 15 after receiving the shot. I?m having a very difficult time sleeping due to the discomfort.

"Moderna COVID-19 Vaccine EUA" Received second dose at ~3pm on 1/26/21. Symptoms began ~6am on 1/27/21 (~15 hours post vaccination). Symptoms experienced included: significant injection site pain, axillary tenderness, headache, fever, body/flu-like aches, nausea, and significant back pain resulting in missed day of work on 1/27/21. Fever, body/flu-like aches, nausea, and back pain persisted on 1/28/21 resulting in leaving work 3 hours early on 1/28/21. All symptoms were gone by ~5am on 1/29/21 (~47 hours hour post onset of symptoms; ~62 hours post vaccination).

2x3 in erythematous raised circular rash, pruritic- lasted 3 days and improved with oral Benadryl not with topical Benadryl, ibuprofen, or tylenol

Employee described history of rash to hands, arms and abdomen that initiated after 1st dose, but didn't attribute to vaccine or report at time of 2nd dose vaccine administration. Was being treated as "eczema" due to hx of eczema. Three hours after receiving second Moderna dose developed a bloody nose, neck pain, back pain, chills; and rash to hands, arms, stomach "worsened" per employee. She reported to ER for evaluation and had COVID test which resulted negative; no additional treatment per employee. Has subsequently followed up with her primary and continues with eczema cream, no additional treatment.

Hives (red, itchy rash) at place of injection. Size was approximately 4 inches in diameter. Rash started 6 days after vaccination and has lasted 6 days so far. Use of diphenhydramine every 6 hours helped ease the itch and redness.

Left arm at injection site, swollen, red, hot to touch, very itchy spot. About 1in tall by 3in long. Began about 1 week after shot, accompanied by a bruise

Left arm got a large red splotch a bit smaller than the size of my hand at injection site on Wednesday and got slightly bigger. Lasted 1 day then slowly disappeared on its own.

Severe migraine that needed a toradol shot, a few weeks later the injection site was red itchy and inflamed. Site still hurts but no longer has itchy Ed?s or inflammation.

Employee states within 5 - 10 min. developed profuse sweating, dizziness, shortness of breath, nausea, vomitting, fatigue, confusion, chest pain and felt panicked. Symptoms waxed and waned. After 45 minutes went to Emergency Department and they completed and EKG, no meds, no labs per employee. Developed rash on her chest while waiting. Symptoms eased by 7pm and she was sent home. Continues with intermittent tightness in her chest, shortness of breath and heartburn since vaccination. No history of anxiety or panic attacks in past.

Erythematous rash and urticaria that started on anterior neck and spread to eyes, cheeks, forehead, ears. Rash lasted about a week.

Red rash With irregular border at injection site. Hot and firm to touch. Appeared 4-5 days after vaccination.

Moderna COVID-19 Vaccine EUA In addition to arm soreness and headache (which I also experienced following my first dose of the Moderna Covid-19 vaccine), I have a raised, firm, very warm, and red area around the injection site (4inches in diameter). Though the red area is not exactly a circle, the diameter of the red area has steadily increased over the past few days. The area is not itchy. My arm is most painful when I move it (attempting to abduct at the shoulder feels impossible) and I cannot apply pressure (leaning or laying on that arm is also tremendously painful, as is the weight of a blanket touching the arm). My arm soreness after the first dose I received resolved after 5-6 days. My arm was firm and warm around the injection site for that dose, but did not have this red area surrounding the injection site.

I experienced a red lump at the injection site the night after my second injection. At first, it was a very large red patch and slowly shrunk and felt like a grape was under my skin. It was hot to the touch, very sore and itchy. It lasted 6-7 days.

Patient reports having hives on her neck, starting the day after receiving her COVID19 vaccine. The hives lasted 2 days, and are no longer present. Patient also reports having dizziness at 3AM the day after receiving the COVID19 vaccines, when she got up to use the bathroom. She is concerned this is from the vaccine. Dizziness occurred once, no episodes of dizziness since. Patient also reports lingering fatigue, starting the night she received the vaccine, until today. (6 days total). Patient called on phone today (2/22/21). No treatment was given. Exam was recommended.

Approximately 12 days post vaccination, vaccination spot became swollen, red, and firm, slightly bothersome and itchy

Covid Arm. On 2/23/21 I had a swollen, red, itchy painful arm at the injection site after no symptoms for several days.

Rash covering neck, arms chest and back. Small red bumps that are somewhat itchy. Rash has slowly spread from first sighting on 2/21 where it started on neck initially.

started: 1-19-21 at approx 7pm, rash to left arm below injection site, reports it raised and hot to touch

Around 2/19-2/20: mildly painful in upper left arm, not at the injection site but more in the region of my triceps. 2/21: slight itchiness in the same region described above 2/22: ~10 days after the 1st vaccine began having red lesions (2) on my left upper arm. Not at the injection site, but the back portion of my arm. Lesions started out painful, firm, red, risen, hot to the touch and pruritic. Lesions got much larger throughly the day and overnight.

GBS strongly suspected Patient received dose #2 of Moderna COVID vaccine on 02/12/21. She had a low grade fever and lower extremity aches that evening. The morning of 02/13 she began experiencing tingling in her bilateral toes. She presented to the emergency department 02/17 because this lack of sensation continued to progress until she had no sensation to her mid thigh and began to be unable to feel her perianal region. Her fingertips also started to go numb. She also reported some diplopia. Received IVIG Somewhat improved strength and sensation on discharge. Discharged to inpatient rehabilitation facility

Initial dose placed 12/23/20. On 12/31 (one day after placing Emgality shot for migraines) red circle on vaccine site injection and rash (inflamed mosquito-like bites) on left leg and right butt cheek. Took Benadryl. Rash on leg and butt cheek disappeared after a few hours. Reddish ring around injection site.

employee c/o shakiness, rapid heart rate, headache and itching after receiving Moderna Covid-19 vaccine. Evaluated by EMS on site. benadryl 25mg administered PO at 14:15pm. family member was contacted and arrived to drive employee home to monitor

Arm pain/soreness began about 8 hours after receiving vaccine, lasted for three days- was at it's worst morning after. Slight swelling and knot at injection site also occurred day after vaccine. Headache began morning after receiving vaccine, was off an on for three days. Lightheaded/fuzziness began two days after vaccine, lasted for 12 hours. Symptoms treated with ibuprofen and cold pack for arm.

Twelve hours post injection: fever, aches, chills, arm pain. 36 hours post injection: lymph node swelling, redness, left arm tingling, edema

Dizzyness at time of injection. Injection site pain, tiredness, Headache, feeling unwell. using ibprophen. Headache relieved after 1 day post injection.

Nausea no vomiting, chills, swelling and itchiness at injection site, warm to the touch, and sinus congestion

She received her vaccine on 12/26/2020. She did not have any initial symptoms to the vaccine. On 1/3/2020 she noticed a small "bug bite" size redness at her injection site that had mild pruritus. This morning the area is more the size of a "sand dollar" It is warm to the touch, but she does not have any other symptoms, denies any fever. Her past medical history includes asthma and anxiety. She is only on Prozac and PNV (she is not currently pregnant). Encouraged to use ICE, NSAIDS, and 2nd generation antihistamine to manage symptoms.

pruritis, erythema, and swelling around injection site; felt like a bug bite, and progressed to become larger, red, and warm to touch

pt began to feel tingling in her left arm and her throat. she felt tightness in the throat and voice was hoarse. she felt ligh headed like she might pass out but did not pass out. she felt chest discomfort with deep breath.

12/31, 08:30pm: Immediate pain & welt developed at sight 12/31, 08:45pm: Slight numbness & tingling in left hand, persisted approximately 12 hours 12/31, 09:30pm (the following s/s persisted in varying degrees until 01/02): exhaustion/fatigue, headache, dizziness, nausea, chills 01/02, 08:30am: chills/cold sweat/fever (temp not confirmed, as my home thermometer had died, but I woke up later that night drenched in sweat as though a fever had broken, and since then my body temp has been normal (no cold chills or hot flashes) and other s/s have also decreased significantly) 01/03: minimal s/s - lingering fatigue, mild 01/04: 03:00a: woke up with cough - uncertain if related (seasonal allergies?)

45-60 minutes after receiving the vaccine she had numbness on the left side of her face/cheek associated with some mild swelling to the area. Maybe some mild left tongue swelling. Normal swallowing, normal breathing. No cough. No vomiting or diarrhea. No rash. She called an urgent care who recommended Benadryl, which helped minimize the tingling sensation and swelling over the next 2 days. Over the following week she had soreness at her left jaw joint near her ear and some left eye dryness. No facial droop. Normal blinking and smiling. No facial muscle weakness noticed. She was not sick when she received the vaccine. No new medications. Tolerates NSAIDs normally without reaction. No facial fillers. Never had anaphylaxis before to anything -- foods, medications, injectables, other vaccines. No known PEG allergy. Has not used Miralax before.

7 days after injection, injection site swollen, red, hot, itchy, began as a few red dots, grew larger and swelled together into a big red blob 8 days after injection, fatigue, runny nose

Fever (max of 101.8), chills, headache, fatigue, injection site reaction (swelling, redness, skin sensitivity)

I had t sit in the room for observation for 1/2 an hour no symptoms. returned to work and no problems. Then about 3 hours after I received the vaccine I started having nausea and some hand tingling on and odd. The biggest limiting symptom was the excruciating shoulder pain on the left arm, no relief with ibuprofen, Tylenol, ice, changing position nothing. Worse pain I had in my life. I could not move my arm on its own at all and it was excruciating pain. Went to the ER and they gave me IV fluids and tramadol. The pain was better after that but I still could not move the arm and the pain was still present. They made me follow up with my PCP. I saw my PCP on a Tuesday after being on and off the phone with them on a Mondays. Symptoms have improved but not back to normal.

Injection area mid upper arm. Edema to injection area , discoloration, 2 inch circular demarcation, pain to local area, itchiness numbness and tingling to left hand during first 7 days. Day 8 hard mass at injection site, rash, discoloration still present. Itchiness still present. PO benadryl taken, topical benadryl applied when PO not taken. Minimal relief from benadryl.

Injection site reaction had resolved. One week after the vaccine my injection site reaction returned with itching, swelling, redness as a firm bump in an odd shape around the injection site.

On 1/4/21 the event follows: 11:37am I got the vaccine 11:50am I got symptoms of tingling with numbness in lips and fiery hot in injection site 12:00pm tingling in left arm below injection site to finger tips 12:20pm felt like my arm was asleep 12:54pm I was given diphenhydramine (Benadryl), fatotidine (Pepcid), and prednisone (deltasone) 1:25pm my left shoulder moving up my neck behind left ear started having pain 1:40pm I was given ibuprofen (Motrin) 2:28pm I was told the symptoms left were known/normal and I am to watch symptoms and take Motrin and Tylenol as needed. Around 4pm made it home and went to sleep. 9:20pm I woke up pain was minimal and went back to sleep. On 1/5/21 I woke up @6:35am and pain was minimal in injection site no other symptoms. Throughout the day I started feeling more pain but was bearable. @6pm my arm was in pain and hurt to touch @7pm I decided to look at my arm and noticed a red ring around injection site

Today is 8 days after covid vaccination. Skin is raised and red about 4 inches around injection site in right arm. Injection site is sore to the touch.

"I received my first dose of the covid vaccine yesterday, January 4th around 3pm. I have not felt any major symptoms or side effects aside from pain at the injection site. This afternoon I noticed how sore my arm was and started looking up potential side effects of the vaccine to see how long I should expect pain. I was trying to practice lifting my sore arm and then started feeling light headed. My vision went blurry, my hearing was muffled, and I started to feel like I was going to faint and/or vomit. I tried drinking water to see if that would help and when it didn't I called over to my coworker to tell her I felt like I was going to pass out. She informed our boss, who called Employee Health. They both walked me downstairs to Employee Health."

1.5 inch x 1.5 inch red, swollen, hard, and warm area located about 2 inches from injection site. Area was noticed at 3:00pm 7 days from vaccine date as it was itching - a new symptom.

Around 1/5/2021 started feeling slight tingling of R foot which has carried on till present time 1/6/21 0600. Around 1/5/21 2100 started experiencing frequents stools leading to persistent diarrhea until present time.

Extreme fatigue day of vaccine. Headache, fever, body aches, nausea, dizziness two days post vaccine. One week post vaccine developed redness at injection site. Redness has been spreading and is warm to the touch. Pain at the injection site and radiating up and down left arm.

I received my first dose of the Moderna COVID-19 vaccine on 12/29/2020 and to date, have had mild symptoms, which I have reported via the V Safe Check Ins. To date, I experienced some injection site soreness with redness for a few days post vaccine and had minimal swelling on the day after vaccination. This evening, I noticed a sudden onset of severe swelling at the site of the injection accompanied with redness, which as noted above, had previously resolved approximately 3 days post vaccination. In addition, the area surrounding the injection site is now warm to the touch and is mildly itchy. In taking the temperature of the injection site versus the rest of the arm, it is running about 3 degrees warmer than the rest of my arm.

Mild rash- anterior neck and left forearm associated with skin tingling; resolved within 15 minutes with Benadryl 25 mg po x 1 dose

Moderna COVID-19 Vaccine EUA 01/05/21 started itching on injection site, 01/06/21 @07:20am noticed redness and hot to touch on injection site, @08:30 started with pain and right arm feeling heavy with swelling. @ 11:05 am noticed injection site swollen (like a large welt and hot to touch). Currently at 4:48 pm injection site still swollen (RED) and hot to touch. Right arm has pain and heaviness.

Notes vaccination at site lower than the deltoid (mid triceps area). Noticed bruising at the site, then a few days later developed redness, and itching over the area. No other symptoms.

On January 6, the area around the injection site started itching. I then noticed it was more tender. The area is now red, raised, swollen, tight and warm. The area is about the size of a deck of cards. I have now taken 50mg of diphenhydramine PO and 1000mg of Tylenol PO.

So I got the vaccine Monday night after work. Tuesday and Wednesday I ran a super high fever, body aches, lymphnode swelling on that side. No big deal . Well Thursday morning I woke up with a rash on both of my legs and my legs swollen like tree trunks. It?s a petechial rash. I called the pharmacist told to take Benadryl and Zyrtec since Friday. So I went to the doctors last night since I still have this rash and it hasn?t gotten any better with Benadryl and Zyrtec. I got blood work done today. And I have to get an arterial and venous Doppler done on Wednesday next week. They are concerned I may have blood clots since my legs are so swollen with a petechial rash. They are also giving me steroid tapper.

Soreness at injection site day 2 that resolved. Diarrhea days 5- present. Hives surrounding injection site started day 9 post injection.

Staff waited the full 30 minutes with no issues. At the 15 minute mark, her injection site was assessed by RN and was found to be without edema or erythema. At the 30 minute mark, the staff proceeded to her office. Upon arrival, she began to feel light-headed, and a co-worker noted that she had red areas on her chest and arms. The staff immediately returned to staff development for assessment, presenting with pronounced erythematous areas on her chest and upper arms, none noted on the stomach. The staff denied any problems breathing or swallowing. Throat appeared wnl upon inspection. Lung sounds were clear upon auscultation. Physician contacted, and 100ml Benadryl IM administered. Staff monitored until EMS arrived. 1343 T: 9.6 P: 132 R: 24 BP: 152/93 O2: 99% 1351 T: 97.6 P: 127 R: 21 BP: 148/96 O2: 99% 1400 T: 97.2 P: 121 R: 20 BP: 149/103 O2: 98% 1402 BP: 142/98 1417 T: 97.4 P: 157 R: 20 BP: 150/90 O2: 99%

Starting on 01/04/21 Employee noticed red swollen area below injection site. States itching warm to the touch. Area is 7 X 4.5cm on posterior of left arm not deltoid. States took 2 doses of Benadryl with minimal improvement. Explained conservative interventions including, cool compresses, IBU and OTC allergy medication if allowed by PCP. Employee verbalized understanding and will continue to monitor site. Employee advised to contact patient safety as the injection was misplaced by the vaccinator.

Very minimal pain after initial shot on 12/29/2020. Pain subsided and I was well for 6 days no reactions. On 1/3/2021 my armpit became very swollen and painful, on 1/4/2021 the Right arm where I received the injection became severely painful, dull throbbing ache from shoulder down to my fingers. On 1/5/2021 my Right arm was now swollen, hot to the touch and a small red circle was forming on my bicep and pain continued to worsen. Today 1/6/2021 I saw my primary care physician that confirmed there is swollen lymph nodes in the arm pit and swelling at the site. The redness of the spot increased in size from the size of a dime to now the size of a half dollar.

1 week and 2 days later my arm where the injection was given is red, painful, swollen, warm to the touch, and itchy

Per patient report, localized reaction started a few hours after. Continues to worsen. Arm now large, swollen, about the size of a golf ball per patient. Red and hot to the touch.

Rash started on 1/6 around the injection site. Developed into L axillary lymphadenopathy, fatigue, myalgias, and headache. Erythema does recede with benadryl but does not resolve. was a little wheezy on 1/6. She has h/o anaphylaxis due to latex and has an epi pen

Warmness and tingling in arm and face. Redness to face and chest. Informed to seek medical help if any further symptoms arise with concern.

on the day of the vaccination 12/30/20, I experienced an allergic reaction on both of my feet. they both were swollen with red blothches. 1/6/21 I noticed that my arm was swollen and red, I have a big red blotch at the injection site.

1/5/21: Developed redness and warmth around vaccine site 1/7/21: Began treatment with clindamycin 300 mg TID x 7 days

Day 1 - Soreness at injection site (left deltoid) Day 2 - Soreness at injection site (left deltoid), fatigue, bilateral lymph nodes below ear and behind jaw sore Day 3 - Soreness subsiding, fatigue Day 4 - Soreness to injection site absent; lymph node(?) soreness and pain lateral chest/breast area anterior to axilla Day 5 - Soreness to lymph node remains Day 6 - Soreness to lymph node subsiding Day 7 - Soreness to left deltoid returned. Day 8 - Large flat area of erythema around and below injection site appeared, hot to touch.

Day 2: arm pain Day 8: new onset skin reaction at site of injection and below (left deltoid); swollen, red, itchy/painful, 3 quarter-sized hives

Fever (chills and sweating) Sharp pain in arm of injection Nausea and vomiting Full body aches Low energy

Had typical fever, chills, body ache & headache first 24 hours after vaccine. 48 hours later arm got red, hard and swollen below injection site. was painful to touch. a few hours that had splitting headache and neck pain and stiffness. had lab work done- all normal. took prophylactic antibiotics. arm was itchy now better.

Hives-like appearance on both arms within 10 minutes of administering vaccine. Resolved by itself in 30-40 minutes.

I RECIEVED THE VACCINE ON 12/29 @ 0900. THAT AFTERNOON I DEVELOPED A HEADACHE AND EXTREME FATIGUE. THE NEXT DAY 12/30 I DEVELOPED REDNESS AT INJECTION SITE AND STARTED TO BECOME HOT AND ITCHY. IT IS NOW 01/08/2021 AND I AM STILL BATTLING HEADACHE AND INJECTION SITE SORENESS.

Initially bleeding and swelling at injection site (believe it hit a blood vessel), immediately hit with a wave of dizziness, fast heart rate and tingling in throat. Since being home injection site has bruised and I have red streaking down the front of my arm with terrible pain and swelling.

Moderna COVID-19 Vaccine EUA Dose 1 One hour after receiving injection- light headed, dizzy, trembling, hot flashes, extreme nausea, confusion, hard time speaking, skin numbness and tingling at injection site and on face/neck/arms. Took Benadryl (diphenhydramine). Acute symptoms dissipated after a couple hours. Continued to feel dizzy when standing/walking. Confusion/short term memory loss of entire afternoon evening (told by others- can?t remember actions, repeating myself and not remembering, can?t remember conversations). About two hours after injection, extreme muscle pain in left arm. Couldn?t lift or move arm and hurt even when not moving, took 440mg naproxen. Brought pain down to a more normal feeling of post shot soreness.

Patient had redness with hive at injection site for about 48 hours post administration. On 1/6/21, the patient took a dose of Miralax and had an anaphylactic response and was treated in the ED department

Pt developed firm, tender, indurated area at injection site 2cm after initial soreness wore off about 2-3 days ago. Also having some night sweats and mild sweating during the day. Temp of 99.3.

Pt had reaction of redness and swelling to injection site. Second day of reaction increased swelling at injection site as well and lymph nodes in this arm swollen. Also stated it was hard, warm and swollen.

Site of injection remained swollen for 8 days. On day 8, site become red, hot, and itchy. Area of swelling and redness increased throughout the day, about 11 cm.

patient had redness and itching at the injection site spreading to the entire arm. Redness further spread up the neck and patient had a tickle in her throat. Pulse 101, BP 126/88 and O2 was 98%. Pt was given an ice pack and benadryl then monitored until redness had receded and itching resolved. Pt given instructions to go immediately to the ER if symptoms resumed or she had other allergic reactions. Pt was also instructed to dose with benadryl at bedtime.

patient received the Moderna vaccine at 4:30 pm. Patient waited in observation lot for 15 minutes and proceeded to vacate the area. Patient returned to the site at 5:35 p.m. with hives on neck and tingle in throat. Pulse 92, 02 95%, and Blood pressure 142/92, and temp at 98.3. Patient has history of reaction to welbutrin. Patient administered 50 mg of Diphenhydramine HCL at 5:38 p.m. Pulse at 92, 02 99%, BP 134/84 and temp 98.4 at 6 p.m. Patient recovered and left in her friends vehicle at 6:53 p.m.

rash and itching on both eyes. Administered Benadryl IM 50mg as ordered by doctor. Was kept under observation for 15 min. Patient left in stable condition.

Exactly one week later, bumpy redness/rash, itchiness, swelling and tenderness right below injection site. Left upper and forearm started hurting 5 hours after initial symptom was noticed.

Hours after shot I noticed a large red swollen lump. On 12/31/2020 I showed this to one of my providers and he told me to give him a call if it had not disappeared by 1/4/2021. The redness was slightly better on 1/4 but then became drastically worse on 1/5/2021. I had a low grade fever(100.7), spreading redness, pain, itching, and swelling of left arm, on 1/5/2021 and was told to go to urgent care. I went to urgent care on 1/6/2021 and was diagnosed with cellulitis. My injection site was measured and I was instructed to go to the hospital if after given first and second dose of antibiotic, symptoms did not improve. Redness began to decrease and I did not go to the hospital. As of today, 1/9/2021 my left arm is mildly red and swollen.

Itching, erythema, warmth and pain over the left arm deltoid muscle. Pain is described as a sore ache that radiates down the arm.

Received vaccine on 12/31/2020, developed mild arm pain following day at injection site. On 1/05/2021, developed mild lip swelling around 1630, that increased to hives on upper back and hips. At 2030, lip swelling had significantly increased and throat felt ?weird? and tight. Fiancé drove to Emergency Department, was deemed not necessary to have epinephrine at the time. Discharged with four day course of prednisone and famotidine. On 1/09/2021, returned to Emergency Department for bilateral hand swelling, increased hives on arms, back and sides. Epinephrine 0.3 mg administered IM right thigh, discharged with another script for prednisone. There were no other changes to lifestyle including lotions, body washes, perfumes, food, etc. that could have potentially triggers reaction.

Within the hour of the symptoms (noticed around 5:15pm) I started to have a rash on the left side of my neck, along with small red dots on my chest. My throat was tingling ajd I had what is best described as ?on and off? rushes throughout my body. I returned back to the site where I got my test from and reported my reaction somewhere around 5:30. I was given 50 mg of Benadryl and told to have friends come and pick me up and drive me home. Around 8pm I was having slight tingling in my throat however it was mentioned it could be the after effect of the sensitivity to the vaccine. I was advised to not have the second dose.

Moderna COVID-19 Vaccine Approximately 25-30 minutes after receiving the vaccine, I developed angioedema of the face, mouth, and tongue. I required epinephrine and diphenhydramine. Approximately 3.5hrs following the first dose of epinephrine / diphenhydramine, I had a rebound reaction and new dysphagia and went to the emergency department where I required another dose of epinephrine, IV famotadine, IV diphenhydramine, IV dexamethasone, and IV odanestron to bring the symptoms under control. No local reaction at the injection site. Angioedema, urticaria, and dysphagia were all solely focused to the head, face, and mouth.

On day 0 of receiving the vaccine I experienced arm pain at the injection site and extreme fatigue. I went to sleep at 9pm and awoke at 1am with chills. My temperature was 99.5. Throughout day 1 after the injection, I experienced more fatigue, arm pain, chills, headache, and overall body aches. I did not take any medication to relieve symptoms. On day 2 I awoke with just a minor headache. Arm pain improved significantly, but is still present.

Patient was administered vaccine at an off hospital site. Patient acknowledged anxiety prior to vaccine administration. Following administration of vaccine, paatient reported that felt tingling in both hands, followed by lightheadedness, tunnel vision, dampening of hearing; was then moved from post vaccine observation area to an exam room. Patient complained that tongue felt swollen and numb and complained of difficult breathing Patient received Epinephrine 0.3mg SQ by the Physician Assitant; ambulance then requested. Stated that she felt relieved after receiving Epi pen, but heart racing and shakiness. Evaluated by paramedics; BP134/80 HR 85 spo2 100% and transported to local ED for suspected panic attack.

Redness starting from injection sight going out word that has worsened since getting vaccine 2inches by 3inches wide approximately now

10:33p started with flushed feeling, dizziness and nausea ,no sob,150/90,83,96 given H2O 10:45p symptoms improving still flushed and hot, more H2O 158/108, 79, 98%, 10:50p feeling better,not flushed or hot feeling,149/96 78,98% stayed 40m, called 01/08 vm patient called back feeling better just sore arm and minor swelling at injection site. told to call PCP or 911 if symptoms return and are worse.

12/29/2020-12/31/2020: Two days after injection of vaccine, left arm was very sore/achy. 1/6/2021: Noticed left arm near injection site was red and inflamed (not raised). - treated with oral benedryl and applied hydrocortisone cream and ice pack 1/10/2021: Itchier, hot to touch, red and welt-like - treated with oral benedryl and applied hydrocortisone cream and ice pack 1/11/2021: Still hot to touch, red and welt-like - plan on treating with oral benedryl and applying hydrocortisone cream and ice pack

I experienced a very sore arm for about two days after injection on 12/29/2020-12/31/2020 By 1/6/2021 I had noticed near the injection site it was red and inflamed. It was slightly itchy, but I put some cortisone cream on it, kept an ice pack on it and went on with my day. 1/10/2021 during the evening I noticed my arm really warm and the rash had then raised to a more hive/welt like look to it. Still not too itchy but still concerning. On 1/11/2021 It was still red and swollen so I had a PA-C that works near my office take a look at it and they said I should report it accordingly to be safe.

Shot given above deltoid muscle. immediate pain, swelling, hot to the touch. symptoms on day 4 with slight improvement still with swelling, pain in arm/neck, warm to the touch. taking ibuprofen every 6hrs with ice. went to work site clinic and was told vaccine administered in shoulder bursa.

after 48 hours, pain, redness, swelling, and subjective fever. pain progressed to limiting range of motion and pain radiating down to the left hand. By the Jan 6th, there was a 7 cm diameter patch or erythema consistent with cellulitis. Patient was started on clindamycin with improvement by 01/11/2021

1/5/21 developed redness, pain and warm to touch on injection site. No itchy, temperature or other symptoms.

7 days after receiving vaccine, severe itching, redness, swelling and pain appeared at injection site. These symptoms were not present the first 6 days after the injection.

Arm became red, swollen, warm and hard. This lasted approximately 7 days. Arm is still somewhat red, warm but has been improving 2 weeks after vaccination. Also had mild chills, body aches, temperature of 99 degrees F at night for 2 days following vaccine administration.

Arm pain on Day 1. Difficult to lift even light objects, painful to the touch. Applied ice and took a pain reliever. Red blotchy rash on chest and cheeks that subsided after 1-2 hours. Arm only slightly sore by Day 2. On day 2 fatigue and dizziness in the morning. Headache, body aches, and advanced fatigue by afternoon. Day 3 all symptoms subsided.

Client reported she experienced pain at the site of injection, nausea, anxiety, tachycardia with HR 140 BPM within 12 hours. On 1/7/20 she experienced severe cervical, clavicle pain with lymph node swelling on right side. Client reports she was assessed by APRN-NP at the Medical Clinic

Injection site rash, redness, minor itching and swelling along lateral aspect of left upper arm, starting at injection site and moving to front of arm. Noticed it this morning, 1-12-2021 and I got vaccine 12-30-2020

One week after the injection, the site became very red, swollen, and itchy. They skin is also raised. It does not happen every day but it comes and goes

Patien called today (1/12/2021) and stated that at approximately 3:00pm yesterday, after receiving her COVID vaccine at 12:30pm. She states that she developed a rash that was itchy. She states it was on her sides and abdomen and patchy. She states this morning she woke up and her lips were slightly swollen and she feels like she has pins and needles throughout her body, and that sensation is intermittent. She states her throat is also itchy. She denies any difficulty breathing, throat tightening or shortness of breath. She is taking Benadryl and has called her PCP and is waiting for a call back from Dr. r

Pt. states day of vaccine, injection site developed with hot, red swelling, decreased the next day to purple color and still hot, currently there is a rash that is very itchy. She is taking Benadryl , Motrin and applying ice. Informed pt. to present to the UC now or contact PC P in the am.

Severe injection site pain, severe body aches lasting greater than 24 hours, tachycardia, severe chills and blue nail beds followed by temperature of 101.7. I was unable to work the next day due to fever and severe body pain that limited my movement. Ibuprofen was taken twice with little impact.

Severe pain in injection site getting progressively worse, fatigue, chills/hot flashes, stomach pain, diarrhea, falling (on 1/12/21 at 8:00 am I collapsed and fell but did not go unconscious).

Skin reaction to the opposite forearm (right). Looks like stretch marks/wrinkles, the area is also itchy. Has been coming and going about 24 hours since I had the injection to present. Have not been able to identify any other cause.

When I first got the shot, 25 minutes later it felt like my left hand wanted to cramp up. That lasted about 3 hours. The. The soreness around the injection started and never went away. Then I could not go to sleep that night, the soreness feeling got more intense. I won?t at 5 trying to get ready but the more I moved my arm the soreness got worse and it started to burn.

presented to clinic on 1/12/21 with c/o left arm redness soreness, warmth and edema approximately 6cm in diameter around the vaccine site. that has not resolved. It started approximately 1/6/21, no itchiness, no other symptoms. She was advised to contact her PMD or to go to urgent care for evaluation. also advised to go to ER if symptoms worsened or are accompanied by any Fever Increasing redness, or severe pain

rash starting on back of hands and then spreading medially towards elbows bilaterally. continuing to spread medially toward shoulders bilaterally. pruritus with rash.

1 week after the vaccine, right upper arm swelling and warmth and pain. Then splotchy red rash on upper arm.

12/31 I had tingling in my throat and was observed in urgent care for two hours with no intervention. It went away by the time I went to bed that night. 1/8 I woke up with a sore arm, did not think much of it and went to work. It was sore all day and when I got home I undressed to take a shower and noticed that it was red, swollen and hot to the touch. I tried hot compresses as I suspected it was cellulitis and marked the borders. It had grown in size the nest morning (1/9) which is when I went back to urgent care and was prescribed 3 days of Keflex. The first dose reduced the swelling and pain in my arm, but by the end of the course of antibiotics it was still red 1/13 I went back to urgent care to be seen for the redness and tenderness. The NP suspected that it may be an immune reaction rather than cellulitis and gave me a single oral dose of decadron with instructions to follow up in 3-4 hours by sending in a picture, and if it did not get better to fill a longer prescription for Keflex. At this point I have taken the prescription to the pharmacy and am waiting until after work to pick it up and begin the script.

1530: arrived for appointment 1545: vaccinated, observed, released 1600: drove back up to site w symptoms after talking to med greeter 1605: we called 911 1614: ambulance arrives 1648: patient departed in POV -fullness in throat -wheezing -hives on chest

Jan 11th around 2100 the site injection became really itchy. Jan 12th at 0630 site injection was red, warm and very itchy. Got hydrocortisone to put over injection site to stop the itchiness. Jan 13th at 0730 the red area on arm was much larger, size of palm, swollen, warm and itchy.

One day following the vaccine I got redness swelling and warmth at the injection site. After 3 days this went away and my arm was back to normal. Now 8 days after the vaccine I woke up with what seems a second reaction, my arm is itching, having pains, has redness, warmth, swelling, and has a quarter size nodule.

Sore arm, ache, headache for 2 days after vaccine. Vaccine site was firm to touch and slightly itchy for a week or so. As of 1/12/2021 a red ring approx. 2 inches in diameter appeared around the vaccine site. Began to fade as of 1/13/2021

headache, fever of 102F, body ache, chills, loss of appetite, redness and swelling at injection site, weak, dizzy, restlessness

1/13/21 Noon, very itchy injection site pea size knot. Today 1/14/21 knot increased sized to half dollar coin size, very red, hot to touch, itchy and painful.

8 days later appearance of a large raised red area on site of injection that grew larger over the course of several days. Spot was very hot, itchy and painful and patient advised had muscle/join aches in legs and a migraine. Went to patient first and was diagnosed with cellulitis of the injection site.

Developed soreness and pain at the injection site about 30 minutes after injection. After a couple hours, the pain became unbearable, and she had an ED physician look at her arm. She had limited use of her arm on Monday 1/11 and Tuesday 1/12. Wednesday 1/13 her arm started to feel better and she could lift it. She went to her PCP and he said the injection site looked higher than it should have been. Today 1/14 she still has sharp pain with movement and limited range of motion.

Patient became dizzy with prickly sensation on back. No skin changes, no oral swelling, no shortness of breath, no difficulty swallowing. Tolerated PO food and fluids, returned to baseline prior to DC.

Possible delayed injection-site reaction appeared 7 days after receiving first dose of Moderna COVID-19 vaccine (IM injection received 1/05/2021, reaction occurred 1/12/2021-1/14/2021). No unusual symptoms noted in the first 6 days following the first dose, aside from minor pain normally associated with vaccine injections. On day 7 (1/12), I noticed a red, slightly inflamed circle expanding out from the injection site to about 2 inches diameter. The site was was slightly painful and hot to the touch (almost like a moderate sunburn), and grew about a half-inch over day 8 (1/13) before starting to dissipate on 1/14/2021. No other associated symptoms.

Similar to an injection site reaction that didn't appear until over a week after receiving the vaccination. Large raised, red circle around the injection site that is very itchy.

Site reaction. Red and swollen. Reaction went away 3 days later but has just returned 7 days post injection

flu like symptoms burning sensation on the right side of the head injection site elbow has a red circular raised area, almost the size of her fist slightly itchy

one week after the vaccine I developed an approximately 6 cm x 6 cm red, warm, itchy local skin reaction at the injection site

1/5/21 symptoms began. She reports swelling, itching, warmth and burning at the injection site and surrounding area. Patient is still having the same symptoms.

Experienced head to toes hives (urticaria) the nights of the 12th and 13th of January 2021 that lasted for about 3 hours. Hives were severely itchy, however resolved on their own without treatment following both instances. No other symptoms associated.

Large circular rash/welt appeared near injection site pain s/p 7 days after injection. Also, continued joint pain and fatigue (10 days out from vaccine today).

Numbness in left arm, tingling in left leg and a heavy feeling in left lower leg with decreased strength in left leg.

Oval, round shape red rash about 3 inches in diameter at injection site 1 week after administration. Smaller size rash was present for days 1 and 2 after administration with soreness, and then went away. Now, 1 week after administration, this larger rash reappeared. It is hot to the touch and itchy, arm is sore again after no soreness for 5 days.

Redness and itching from my chest to my head 3 hours after receiving my vacation the foray I woke up feeling fogy and not like my self.

Sudden pain and swelling at injection site. Then became very itchy with hives on arm. Itching of face and legs. Rash on arm at injection site turned into welts. All improved with Claritin and Benadryl , still have mild pain and redness at injection site (no symptoms this AM)

Swollen hot itchy red rash on arm at injection site. Spread across arm, neck, ear and cheek on left side.

fatigue began later in the evening of 12/29/2020, Headache began 12/30/2020 worsened throughout the day and "flu like symptoms", 12/31/2020 continued with fatigue, redness and knot at site of injection. 1/1/2021 itching at site, redness with a ring appearance around injection site. Had ED visit for symptoms 1/1/2021, given Benadryl and an antibiotic.

numbness/ tingling in both hands, started 6:50 pm (20 minutes after vaccination) resolved by 7:02 pm.

pain at injection site occurred an hour after injection and persisted into next day and continued to increase in pain and becoming tender to touch and movement. Muscle soreness throughout body, joint pain throughout body, chills and fatigue occurred previous day and continually persisted

7 days after initial vaccination, developed a rash with redness, swelling, tenderness, and itchiness.

Moderna COVID-19 Vaccine EUA. It?s been a week since vaccine and injection site is red,bumpy, and and itchy. My body has been feeling somewhat itchy but not sure if it could be related to that too.

Rash on bilateral arms and bilateral inner thighs that began on 1/7/2021. Rash is red, itchy and painful. Was prescribed Triamcinolone cream to apply to areas 2 times a day with no relief. Have tried hydrocortisone cream with no relief as well as OTC benadryl with no relief. Continue to have painful rash today on 1/16/2021.

On 01/09/2021-swelling on the injection site redness and itching, symptoms resolved on 01/11/2021. Today 01/17/2012 at 08:30a.m I woke up with redness at the injection site mild swelling and itching

Right arm numbness/tingling. Decreased to 2 fingers after 30 minutes of monitoring. 01/14/2021 starting having sporadic HA until today 01/18/2021.

01/19/21 6am- intense pain at injection site and small blue bruise. 10am- body aches began, upset stomach, swollen tonsils, scratchy throat, very tired, unable to move right arm without pain and very tender to the touch. 12pm- worsened all symptoms listed above 4pm- body aches starting to get better, still experiencing intense arm pain and scratchy throat 9pm- headache began. Took 600mg ibuprofen and went to bed 01/20/21 6:30 am- woke up with a headache, right arm feeling much better but still some discomfort. 9:30am- headache. Took 800mg ibuprofen 1:00 pm- all symptoms have subsided

After receiving the vaccine I felt HOT, JUST NOT RIGHT. IT WAS ABOUT 30 MINUTES DRIVING HOME WHEN MY THROAT SWELLED UP. DIFFICULT DRINKING, MY BODY BECAME VERY ITCHY. I PULLED OVER TOOK A BENADRYL. MADE IT HOME AND TOOK 2 MORE BENADRYL. FOLLOWING DAY I FELT SO DIZZY, WEAK STILL ITCHY WITH SWOLLEN THROAT I TOOK 2 MORE BENADRYL THAN ABOUT 2PM I HAD TO WAKE UP TO PICK MY DAUGHTER FROM SCHOOL JUST FROM WALKING DOWN THE STAIRS I BECAME SO DIZZY, MT FACE WAS FLUSHED. HAD NO CHOICE BUT TO CALL AN AMBULANCE AT THE HOSPITAL THEY GVE ME A EPIPEN FEW HOURS LATER SENT HOME. 3 DAYS STRAIGHT MY THROAT STILL SWOLLEN, FATIGUE JUST NOT MYSELF. BUT I CANNOT SEEM TO GET ANY HELP. MY PRIMARY CARE DOCTOR DOESNT KNOW ANYTHING SHE IS CONSTANTLY GOOGLING EVERYTHING. I CANNOT TRUST WHAT SHE SAYS AS SHE DOES NOT SEEM VERY EDUCATED. I NEED A NEW pCp . WELL ANYWAY I NEED TO KNOW WHAT I AM ALLERGIC TO AND IF IT IS SAFE TO GET THE SECOND VACCINE. ALSO HOW LONG ARE THESE SYMPTOMS SUPPOSE TO LAST BECAUSE I NEED TO GET BACK TO MY DAILY ACTIVIES AND WORK BUT DOING BASIC CHORES ETC WIPES ME RIGHT OUT. I NEED GUIDANCE ASAP

Began experiencing a rash about 3 inches in diameter on Left Arm below injection site about 7 days after first dose of Moderna COVID vaccine. Rash itches and has grown in size over the last 2-3 days.

Large area of induration, redness and tenderness at site of injection that began 1 week after the dose, lasted about 2-3 days. No fevers, no systemic signs.

One week after receiving the first dose of the Moderna COVID vaccine my upper arm developed an oval shaped rash around the vaccine injection site. The next day it had grown in size and was itching.

Starting at 10:00 AM the next day after being vaccinated I started to get the chills, headache, and extremely fatigued. I checked my temperature and it was 101.3. The temperature continued into the next morning but did break by Friday. On Thursday the injection site was very swollen to size of golf ball. It was hot to the touch. The swelling has gone down but on 1/19/21 the injection spot had hives and was very itchy. There are no hives as of today 1/20/21.

Vaccinated on 1/11/21 and on 1/18/21 I developed redness, warmth, and itchiness at the vaccine site, worsened the next day, applied topically hydrocortisone cream and redness and itchiness decreased 1/20/21

no side effects after shot other than sore arm until 8 days later when the injection site became red, warm and a little swollen. Appears less red today than yesterday but still warm and swollen. No other symptoms and feeling healthy otherwise.

1/14/21-Patient received moderna vaccine to left arm and on 1/19/21 at 09:00 am noticed swelling, hard to touch, warmth, big red circle 2 inches by 2 inches, and itchy. Denies taking anything for it. Pt. states that it seems like symptoms are getting worse-rash is getting bigger, more itchy, and more swollen.

C/o lightheadedness, frontal headache 4/10,numbness/tingling of left fingers only, bilateral lower extremities heaviness mild from hips down to feet, "states I just feel off". Ambulated short distance to parametics handoff. BP 132/64 HR 70,O2 98%, alert and oriented x3, denies itchiness,hives, difficulty swallowing. Vitals remaining stable over 45 minutes of evaluating, with numbness in left hand subsided, H/A remains at 4/10, able to stand with remaining heaviness. Patient has declined transport to the ED, although has called for ride home(awaiting).

COVID-19 Vaccine EUA; Over a week after first vaccination, the injection site appeared red and inflamed in an uneven circle, about 3 inches in diameter. I also felt a resurgence in headache and muscle pain. The redness decreased over the following 3 days and muscle soreness subsided after 24-36 hours.

High fever, rigors, chills, arm swelling and pain, arm redness. Neck and back pain . All side effects still present 48 hours out

I got the vaccine on 1/15/2021 felt fine afterwards. A little sore arm Saturday morning but nothing too crazy. Starting 1/21 the site started to itch, & kept getting worse. I noticed morning of 1/22 it was welted, all red, bumpy & warm to touch. I notified the lady who gave it to me & she said I could be having an Immune reaction to it. Advised to take an allergy pill. Ended up around 1130a taking 1 Zyrtec. Welting went down, now its almost like a spotty rash, still warm to touch.

Moderna COVID-19 Vaccine EUA Fever of 101 degrees F, Intense Fatigue, painful upper arm on injection side, chills, loss of apatite. Shot was administered in the evening, I woke up with symptoms the next day that progressively got worse into the evening, the following day (2 days post vaccine) I woke up feeling fine with very little soreness at injection site which gradually subsided over the next couple of days.

Pain to injection site immediately following injection. Hot/ red injection site 7 days after injection. Swollen painful lymph node under arm pit of left arm (same side as injection)

Rash all over body but mostly on face 12 hours after administration; not itchy; chills right before onset of rash; no shortness of breath; antihistamines are not helping reduce rash

Started on 1/18/21 as two separate whelps, red, raised, warm and itchy. Now is one large red rash, large whelp on arm. Been taking Benadryl. Went to walk-in, who told her to take antihistamines, Benadryl or cream to local area.

Swelling and redness at injection site, dizziness, fatigue, body aches, chest pressure, difficulty breathing, nausea- currently lasting almost 2 days

Within 30 minutes I felt itchy at the injection site. That evening I began feeling pain in my left wrist; I believe it was joint pain. The next day I felt moderate pain, swelling and firmness at the injection site. I was also lethargic and mentally depressed; however, the pain in my left wrist ceased. The third day I had no pain in my wrist or arm, but the muscle around the injection site felt firm and swollen. This is the 7th day and I still have firmness/ swelling at the injection site and experience itchiness.

day 7 after vaccine (1/5/20), about 6p in the evening, site of injection became sore again. mild redness and hard, kind of indurated (2x2 inches in area). little bit swollen, raised. no systemic issues, all localized to site. i applied heat and took zyrtec -- mostly resolved the next morning. totally resolved 2 days later.

five minutes after vaccine developed tingling in left shoulder. ten minutes after vaccine felt tightness in throat, fifteen minutes after vaccine had difficulty swallowing

Hives localized to injection site showed up suddenly, about 1 week after vaccination. Redness, welting about 3 inches in diameter. Took benadryl. Hives began decreasing by the next morning. Completely resolved 3 days later.

Itching on injection site, itching on same side arm and neck. A couple days later noticed a sort of hive surrounding injection site.

Very painful in the area where I got the shot. I usually have a little pain at the site of the injection but this was WAY worse which resulted in me icing the area and taking Ibuprofen. I also could not apply any pressure on the site so I had to make sure I only slept on my right side overnight. The intensity of the pain was MUCH better the next day, and today (2 days later) it is very bearable. I also experienced lethargy the first evening after receiving the vaccine, but that went away the next day. On the second evening since receiving the vaccine, I started to experience body chills and some minor body aches. I felt a sense of general malaise that I often experience when sick.

Anaphylactic Reaction; Significant angioedema; Severe allergic reaction; A spontaneous report was received from a nurse, who was also a 28-year old, female patient who received Moderna's COVID-19 vaccine and experienced an anaphylactic reaction, a severe allergic reaction, and significant angioedema. The patient's medical history, as provided by the reporter, included Hashimoto's disease and thyroid disease. No relevant concomitant medications were reported. On 09 Jan 2021, the patient received their first of two planned doses of mRNA-1273 (Lot number: 039K20-2A) intramuscularly for prophylaxis of COVID-19 infection. On an unknown date, the patient experienced an anaphylactic reaction, significant angioedema and a severe allergic reaction. Treatment for the events included epinephrine, unspecified antihistamines and unspecified intravenous fluids. Action taken with mRNA-1273 in response to the events was not reported. The outcome of the events was considered not resolved.; Reporter's Comments: This case concerns a 28 year old, female patient with medical history of autoimmune disorders including Hashimotos disease and thyroid disease, who experienced a serious unexpected event of anaphylactic reaction, angioedema and hypersensitivity reaction. The event occurred on an unspecified date after first dose mRNA-1273 ((Lot# 039K20-2A) administration. The subject's concomitant medication was not provided. The event was treated with epinephrine, iv fluids and anti-histamines. Based on temporal association between the use of the product and the start date of the event, a causal relationship cannot be excluded.

Approx 10 minutes after injection - pt developed red blotchy areas on neck and arms No itching No SOB. Benadryl 25 mg po provided. Back to surgery where she works.

Case called with warmth and redness at or below injection site 9 days after inject given. Area was about 2'. Encouraged case to call Dr. and report also. Case was seen at physician that day. She was not given any medication at that time but was told to use Benadryl OTC for local reaction. Case called back on Friday to say that area was getting larger. Again HCP had case call doctor. Case was started on Cefalexin 500mg BID for 7 days and that was started on 01/22/21. Case tells HCP that Doctor was not sure what it was but did want to start medication. Case calls again on Tuesday to say that area had continued to enlarge over the weekend but was now starting to fad into a bruised like appearance. No warmth at this time. She is to continue with medication and recheck with physician as advised.

On 1/15/2021 I noticed that at the injection site it was warm, red, and the redness was spreading. I went to my local urgent care who prescribed me antibiotics (Cleocin) 3x for 7 days. I completed the antibiotics on 1/23/2021. On 01/25/2021, I noticed a red rash on my chest, stomach, and inner arms. I returned to the same Urgent Care who confirmed that I am having an allergic reaction. I am prescribed Prednisone and Hydroxyzine.

Initially developed redness, swelling, and pain, resolved after 48 hours. Twelve days after immunization painful, red, swelling returned at the site of injection (4 inches x 1.5 inches) blanchable, associated with headache and whole left arm tingling without loss of sensation or motor control.

Localized redness, warmth, tenderness, and itching immediately following vaccine. Symptoms lessening eventually until 1/26 when large hot, hard, itchy circle appeared covering the size of my deltoid muscle.

Patient describes increased blood pressure, tachycardia, queezy feeling, tremors, tingling/numbness of the lips and eyes, and heavy feeling in tongue and jaw that started to develop ~15 minutes after vaccine administration and worsened overtime. Patient took Benadryl which provided minimal relief, then presented to the ED.

Pt called this date, 1/26/21 with concerns that one week later after her covid vaccination was placed that she is still experiencing warmth, tenderness and swelling to the injection site of the L deltoid. Pt also indicated that she has been having intermittent itching throughout her body and feels generalized fatigue. Pt was directed that should her symptoms worse, or should she feel her current symptoms warrant a visit to her PMD, ER or Urgent care, that she should present to one for further evaluation. Pt denies the need for that intervention at this time and wants to apply warm compresses and give it a few more days. Pt will keep this clinic updated regarding any further reactions or worsening events.

Diffuse and generalized hives Swelling and hard knot to injection site Low temp of 96.5 with chills Bloody sputum from mouth and nares Headache

face was still red; swollen; feeling weak; Tired; Severe allergic reaction; Difficulty swallowing; A spontaneous report was received from a healthcare professional concerning herself, a 28 year old female patient, who received Moderna's COVID-19 Vaccine (mRNA-1273) and experienced a severe allergic reaction, difficulty swallowing, face was still red, swollen, felt week and tired. The patient's medical history included anxiety and allergy to latex. Concomitant product use was not provided by the reporter. On 12-Jan-2021, 15 minutes prior to the onset of the symptoms, the patient received one of two planned doses of mRNA-1273 (026L20A) intramuscularly in an unknown injection site for prophylaxis of COVID-19 infection. 12-Jan-2021, after receiving the vaccine, the patient experienced a severe allergic reaction which made her face puffy, red, and covered with hives. She took 50 mg of diphenhydramine. She was also having trouble pronouncing words because her tongue was swelling and she couldn't swallow water, so she used epinephrine and go to the emergency room. On 14 Jan 2021 she felt weak and tired. On 13 Jan 2021follow up information was received and per source document/call - In addition one day later, on 13Jan2021 around 5:30 pm, patient reported that she went to the bathroom and noticed that her "face was still red" and "swollen" and had a "little bit of difficulty swallowing" and took another unknown dose of Benadryl and felt better. Action taken with mRNA-1273 in response to the events was not provided. The outcome of the events,severe allergic reaction, difficulty swallowing, face was still red, swollen and felt weak and tired was not reported.; Reporter's Comments: This case concerns a 28 year old female with medical history of anxiety and allergy to latex who experienced serious medically significant unlisted event of severe allergic reaction described as her face puffy, red, covered with hives, tongue swelling and difficulty swallowing within 15 minutes after the first dose of the study medication administration (LOT:026L20A). Patient also experienced additional reported events of non-serious listed events of "face was still red" and "feeling tired" and non-serious unlisted events of "face swollen", had a "little bit of difficulty swallowing", and "feeling weak". Patient was treated for the severe allergic reaction with initially Benadryl 50 mg and then with epinephrine pen and was sent to ER. Based on the temporal association between the use of the product and the start date of the events within 15 minutes of receiving the vaccine, a causal relationship cannot be excluded and the event of severe allergic reaction is possibly related to vaccine. Additional reported events of non-serious listed events of "face was still red" and "feeling tired" and non-serious unlisted events of "face swollen", had a "little bit of difficulty swallowing" and "feeling weak" are possibly related to vaccine.

2nd dose Moderna given at 0729 0740 throat felt like closing, bright red flushed 0741 Epi given 131/92 94 0742 head/face shaking rapid eye movements with attempted eye contact, Alert/oriented appropriate in conversation, sitting position 0743 110/83 face redness resolving, flush/red BUE, feeling better 0744 106/76 Rapid Response called 0747 106/68 benadryl 25 given 0751 911 called per Dr. recommended for further eval/potential reactions 0752 129/95 80 99% room air 0756 ambulance here 0801 left via stretcher with EMS to nearby hospital ED, patient tolerated activity to stretcher well 0925 reported by vaccinator of team member return to pick up rest of belongings to go home, tolerated activity well.

After about a week of getting the vaccine my left arm starter a red raised rash around the injection site. It was not itchy. Just red raised rash

After the 1st dose of the vaccine I had a swollen, painful, itchy, red rash appear at the injection site 5 days after vaccination. The rash persisted for 3-4 days before disappearing. The rash reappeared immediately after the administration of the 2nd dose of the vaccine. I became flushed and dizzy during observation and was kept for a longer observation period. My vitals were normal and I was cleared by a nurse after drinking some water and apple juice. The rash has persisted and is about 4 inches in diameter at this time and remains painful and swollen.

On the 8th day after receiving my vaccine, my arm at the injection site was itchy and I felt a small bump. When I looked at it in the mirror, it was swollen and red. It was also warm to the touch. No pain though besides the initial itch. It is about a 1"-2" diameter circle. Today is day 9 after receiving the vaccine and it is still red and slightly swollen but not itchy. No other symptoms present.

Shortly after first dose, patient complained of itching and localized "tightness" in arm at the site of injection.

Temperature (tmax 102.9) Superficial dermal reaction to vaccination site (L arm) at injection site and extending slightly proximally and distally. Severe body aches/pains Nausea without vomiting Generalized fatigue/malaise

Diffuse papular rash to abdomen and right forearm, itchy non-painful, showed up 7 days after administration of vaccine. No new contacts, detergents, exposures, or food. Benadryl helps alleviate symptoms but does not go away. Going on day 4 of rash presence.

I experienced a delayed hypersensitivity reaction at the injection site. On Sunday evening (1/31/21) I noticed a few petechiae at the injection site (~10) but had no other symptoms. On Monday morning (02/01/21) I woke up with a large wheal at the injection site that measured 7cm by 6cm. The area was red, warm and incredibly itchy and uncomfortable. Vital signs were measured and were normal. No treatment was administered, although I may take benedryl later. *Note- no one asked about signs of anaphyalxis etc. when I called saying I was having an allergic reaction. You should add this to the voicemail because it took 2 hours to speak with a person and this could be incredibly dangerous/deadly in other cases.

Dizziness, Headache, Myalgia, Rash, shaking, pale, diaphoretic, dyspneic, pain at injection site Narrative:

Stated she rec'd the vaccine on Jan 23 & woke up on Jan 31st with a few bumps at the injection site. It progressed over the last couple days & is now the size of a soft-ball. Warm to touch. No pain. No itching. She F/U with her PCP @ Hospital today, 2-3-2021 by telemed appointment. She told her to call this health dept because it was our community clinic where she was vaccinated. Treating with claritin, benedryl, pepsin & an antibiotic now for 5 days. She is planning to get dose number 2 when due (per her PCP as well as HD recommendation)

Extreme muscle soreness/inability to move arm. Giant red raised bruising and itchy at injection site. Swollen lymph nodes under armpit. Fever, chills, sweating profusely and very cold the following night. Rash, itching and pain on arm lasted 7 days, swollen armpit lymph nodes lasted 4 days. Fever and chills for 24 hours.

After I received my second vaccine shot, approximately 12 hours later I started experiencing symptoms such as: headache, chills, body aches, fatigue, and was lightheaded. Then approximately 24 hrs later a red mark started appearing on my right arm below the injection site. The red mark has become swollen and painful.

Arm started swelling within five minutes. Arm was turning red, itchy and burned. Neck and chest started turning red, itchy and burning, then spread up left side of face. Started coughing, throat itched, was really dizzy. Nurse sat next to me with an Epi-Pen for a few hours.

Facial edema, oropharyngeal edema; Lip swelling; Throat itching; Tachycardia; A spontaneous report was received from a healthcare professional concerning a 28-year-old female, patient who received Moderna's COVID-19 Vaccine (mRNA-1273) and developed lips swelling, throat itching, facial edema, and oropharyngeal edema. The patient's medical history was not provided. Concomitant product use was not reported. On 15 Jan 2021, approximately five minutes prior to the onset of the events, the patient received their first of two planned doses of mRNA-1273 intramuscularly in the arm for prophylaxis of COVID-19 infection. On 15 Jan 2021, five minutes after the vaccine was administered, at 11:15am, the patient complained of lip swelling and throat itching. A healthcare provider assessed the patient and vital signs included, pressure 132/103 mmHg, heart rate 95 beats per minute, and 100 percent oxygen saturation. At 11:22am, the patient had facial edema, oropharyngeal edema and attempted to clear her throat. Vital signs reported at that time included, blood pressure 143/106 mmHg, heart rate 121 beats per minute, and oxygen saturation 99 percent. Treatment for the event included diphenhydramine 50mg and epinephrine by injection twice. Emergency services were called to transport the patient, however, the patient declined transport. Action taken with mRNA-1273 in response to the events was not reported. The outcome of the events, lip swelling, throat itching, facial edema, and oropharyngeal edema, was unknown.; Reporter's Comments: This case concerns a 28 year-old, female patient, who experienced events of lips swelling, throat itching, facial edema, and oropharyngeal edema. The events occurred within minutes after the first and last dose of mRNA-1273 vaccine administration. Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded and the events are assessed as possibly related.

1 week post-vaccine, my deltoid (injection site) became swollen, severely erythematous and very itchy with a single wheel/welt over the injection site. Lasted approximately 36-48 hours, then swelling, erythema, and itchiness began dissipating .

Full body rash. Started at site of injection site woke up next morning with a completely full body red, itchy, bumpy rash. Went to dermatologist and they said it was from vaccine they prescribed me an external cream to take.

At first, I had normal side effects: fatigue, chills, hot flashes, body aches, injection site pain, and body pain. But yesterday evening on day 3, I just started to have my upper left arm burn, swell, itch, and turn red. I looked it up online and it turns out I have "COVID" arm which is a rare adverse side effect of the vaccination. It said it would subside in 24 hours to a week. This was not listed on any of the forms I got as a possible side effect so I thought I should report it.

Normal AEs -chills, fever, fatigue, and pain at injection site for first 24 hours. Then developed severe SOB and blue hands.

Jaw pain; Syncopal episode/Syncope; Fell; Dizziness; Nausea; Felt flu-like; Injection site pain; Fatigue; Headache; Muscle pain; Chills; Fever; Felt unwell; A spontaneous report was received from a nurse concerning a female 28 year old, patient who experienced same day injection site pain, fatigue, headache, muscle pain, chills, fever, felt unwell and flu-like. On 29/Jan/2021, she developed dizziness, nausea, a syncopal episode and fell and hit her jaw, which developed into pain. . The patient's medical history was not provided. Concomitant product use was unknown by the reporter. The patient received their second dose of mRNA-1273 lot 028L20A on 28-JAN-2021. On 28-JAN-2021 approximately 1 day prior to the onset of the symptoms, the patient received their second of two planned doses of mRNA-1273 Lot number 028L20A intramuscularly for prophylaxis of COVID-19 infection. A patient received her second dose of Moderna vaccine on 28/Jan/2021 at 8 AM, lot 028L20A. Same day at 17:00, she experienced injection site pain, fatigue, headache, muscle pain, chills, fever, felt unwell and flu-like. On 29/Jan/2021, she developed dizziness, nausea, a syncopal episode and fell and hit her jaw, which developed pain. She was seen in the emergency room (ER) and released with a diagnosis of syncope and jaw pain. Resolution dates not reported. Treatment information was not provided/unknown. The patient received both scheduled doses of mRNA-1273 prior to the event(s); therefore, action taken with the drug in response to the event(s) is not applicable.; Reporter's Comments: This report concerns a 28--year-old female who received Moderna's COVID-19 Vaccine (mRNA-1273), Lot # not provided, and within 2 days, experienced injection site pain, fatigue, headache, muscle pain, chills, fever, felt unwell and flu-like, dizziness, nausea, a syncopal episode and fell and hit her jaw, which developed into pain. Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded.; Sender's Comments: MOD21-024340:Crosslinked: Same Reporter MOD21-024360:Crosslinked: Same Reporter MOD21-024368:Crosslinked: Same Reporter MOD21-024387:Crosslinked: Same Reporter MOD21-024396:Crosslinked: Same Reporter MOD21-024411:Crosslinked: Same Reporter

Headache 10 mins after shot.... 2 hours after shot arm became swollen and extremely hot... Along with face becoming red and hot... Became super tired and eyes sunken in... Raised temperature... After 5 hours all of the above subsided besides fatigue

Red, well circumscribed, slightly raised, lesion at site of injection. Approx 2 inches in diameter. Not itchy or painful. The lesion appeared this morning at 9am and is still present 8 hours later.

25 hours post vaccine I had a hive on my lip that started swelling up and what felt like an itchy throat. I took a benedryl and then after about an hour it subsided. I had not had anything but but usually coffee this morning prior to that reaction.

1121 Patient started feeling hot, face red, throat feeling dry and tight. Vital signs: Blood pressure 122/78 Heart rate 88 SATS 99% ON ROOM AIR. Patient was given Benadryl 25 mg by mouth. After about 15 minutes after administration, patient noted her "hot flash" had dissipated and her "funny feeling in throat" had minimized. She denied difficulty breathing or swallowing. Patient was discharged at 12:00. At 12:15, patient returned appearing slightly flushed and complaining of feeling warm again. While accompanying patient to Convenient Care, patient noted her throat "felt funny" and had to clear her throat to speak. Patient was transferred to convenient care nurse at 12:20

8 hours post injection: headache, joint pain and body aches progressively worsened through 48 hours after injection. Arm was sore but nothing compared to joints (especially hips). Temperature was only slight at 98.7. Headache and body aches, joint pain were severe enough that I was forced to rest and unable to continue daily activities. Ache symptoms quickly dissipated after 48 hours, but a 2 inch diameter welt appeared, slightly raised and itching mildly like a mosquito bite. Welt is still present now, 5 days post-injection.

Around 10 or 11 pm, arm pain, chills, fatigue, headache, nausea, swollen lymph nodes, lightheadedness, fainted in tub. Next day, fatigue all day, couldn't talk, or eat. Went back to bed again. The following day hot flashes, weakness. went to ER. Felt like blood pressure was dropping, tingling in legs, difficulty lifting her head.

Bulky painful axillary lymphadenopathy each 1-2 cm on the same side as the injection, erythema and warmth around the injection

Employee became diaphoretic, complained of SOB and tingling from the feet up to her head. She was hypertensive at 159/105, and tachycardic at 115.

Moderna COVID-19 Vaccine Large area of redness at the injection site. Area is raised from the skin and warm to the touch (looks like a large hive). Noticed itching of the skin earlier in the day, prior to discovery of the red area.

Site of reaction started to itch day 2 to3 of vaccination, but I thought it was because my arm was still sore. I don't think I physically saw the rash until day 5ish...It is also around scar tissue so I don't know what /if it has anything to do with the reaction, I drew a border around the reaction on Friday (when I took the picture) and it is beginning to get smaller and look better.

1 week post injection, my injection site began to swell and a red welt has appeared. It is warm to touch.

Moderna COVID-19 Vaccine EUA Injection site redness, swelling, itching, discomfort the size of a fist 7 days after injection.

Redness and swelling next day, which resolved but 4 days later developed recurrent swellingwith nausea and vomiting

The morning of 1/4/20, redness and swelling at the injection was noted. A circular flat ?lump? at the site is present with mild intermittent itching. No treatment at this time.

woke up on day 7 with a red 4 inch red raised mark (cellulitis) at injection site. Progressing to cellulitis ring around injection site.

1/5/21 @8AM: Immediate soreness at site of injection. Unable to sleep through night after injection ~1/6/21 @3:30AM: woke up with chills and sweats

Day one 1/3/2021 of reaction there was a knot and tenderness at injection site, day 2 1/4/2021Redness and itching at injection site (area approximately 1.5-2 inches in width and length. Drowsiness and dizziness were also present on 1/4/2021.

I had patient report that she had localized swelling and lymphadenopathy. I confirmed this on physical exam. She had localized increased warmth over the left upper outer arm where the vaccine was given at the deltoid. There was a raised area of skin in a serpiginous pattern circumferentially 3.5 across and 4.5cm in length. It was blanching and not firm. She had 1 soft lymph node palpable at the left axilla, tender and 1.5cm in size. She has had no other symptoms other than pain at the injection site for 2 immediately days after the injection was given. I advised that she fill out the information for v-safe and asked that she report any further program to both v-safe and our office.

Jan. 4: felt dizzy and sluggish rest of day Jan. 5: injection site swollen, very painful where she was having difficulty raising the right arm, chills, headache, fever Jan. 6: fever and right arm soreness She?s taking over the counter meds

On 1/3/2021 I noticed tenderness at injection site, there was a knot under the skin, on 1/5/2021 the was a red circle around injection site, this area welted up but welting goes away and comes back and is itchy at times, on 1/6/2021 red area is lighter in color, continues to welt up off and on and is itchy at times.

Reaction started on 1/5/20. Site is red, hard, itchy, hot to touch, and raised approximately 2-3 cm. Remains afebrile. Seen by Provider via Telemedicine.

Received the vaccine on 12/31/2020. Symptoms: -Soreness developed later on in the evening and remained very sore and tender for a couple days. -A light headache occurred and went away within a few hours. - After 5 days on of having the vaccine on 1/05/2021 I developed a itching sensation on my arm And developed a rash on my arm (deltoid) where the vaccine was administered. It is a square shaped rash on my left arm.

Several hours after receiving the vaccine I started to break out in hives and felt incredibly fatigued. Symptoms gradually improved over the next two days. Last night the vaccine injection site became hot, swollen, and incredibly itchy. Symptoms have not worsened but have not improved since taking 50mg of Benadryl at 3:30 PM today

Weakness, fatigue, body aches, injection site soreness/became hot, fever rushes, lack of appetite, sinus pressure, post nasal drip

Welps at injection sight, axillary lymph node swelling, swollen lymph nodes in neck and shoulder pain

1/5/20 : 7 AM - and noticed swollen, red, and firm raised area just under injection site. Warm to the touch and slightly itchy like sunburn. 6 PM - Area is doubled in size (about the size /shape of a thumb), much redder, and in a well-defined elongated oval shape. Hot to the touch, firm and painful swelling that made sleeping difficult. Took Aleve and iced it. 1/6/20 7 AM - Red area has spread out into a less defined circle about 2in in diameter. Less swollen and painful but still hot to the touch. 6 PM - Area has spread into tear-drop shape about the size of my palm. Drew a line around the area. Still causes some difficulty sleeping. 1/7/20 - Area is less red and not as painful but I can still feel the original area swollen under the skin and hot to the touch. Spread slowed significantly and mostly stayed in the lines.

A week after receiving the vaccine I woke up with hives like symptoms at the injection site (right arm) and on my chest. There is also a lump that developed on my right collarbone within the past two days.

Generalized itching, scratchy itchy throat, vertigo. She was monitored for 2 hours and symptoms resolved with 50mg oral benadryl

I began noticing red spots on both breasts, then chest, stomach, back, and right arm have began to increase in burning sensation with no discoloration. It feels like I have a rash but no redness or swelling.

I did have a headache and slight fever not to long after I got the shot. The next day my arm was super painful. Several days after the shot my arm where the injection site is was red. It then started going back to normal color. Two days ago it itched a little then the redness appeared back again and now it is hot to the touch.

Onset of chills at around 10pm (normal temperature). Early morning around 4am on 1/3/2021 I was woken up by severe arm pain (arm injected) and generalized body aches. Around 7am 1/3/2021 my temp was 99.7. Around 10am my temp rose to 100 and all morning I had chills. Chills and fever subsided after Tylenol but then I started having chills again around 3pm with my temp raising once again to 99.8. The whole day I also had a headache, generalized body aches, looked flushed, had moderate arm pain on arm injected. When I woke up on 1/4/21 all symptoms were gone.

Pt presented to our office for redness, swelling and painful site where she had received the COVID vaccine from Moderna on 12/29/2020. She presented today, 1/7/2021 with the adverse event. The size of site was approximately 11cm, hard, and warm to touch. She reports immediately after the vaccine, the injection site was slightly painful and sore but went away until 01/04/2021.

Pt received vaccine on 12/29/2020. On 01/05/2021, she noted large, approximately 11cm, red, swollen, warm and painful area at the site of the injection.

Severe pain at injection site (right arm) and entire right arm since 8 pm 1/6/21. And hard nodule/swelling at the injection site noted this am at 5 am, 1/7/21.

Welted, Red, Raised, Swollen, Hot, Change in size/color. Gets better, then gets worse. Large area of effect.

generalized itchiness, itchy scratchy throat, vertigo. She was monitored for 2 hours and these symptoms resolved with 50mg oral Benadryl.

in the subject's own words: I received vaccine on 12/28. on Monday 1/4 I noticed the site of injection was reddened and raised along with mild itching. on 1/6 the redness is twice the size. Patient spoke face to face with subject and another pharmacist together on 1/6. Subject reports it is not painful. she tried ice and she tried benadryl but neither really helped. She showed it to Doctor who described it as erythema but not cellulitis. It is approximately 7 inches in length. on 1/7 she reports it is the same size, less red, not warm and minimal itch.

12 minutes after receiving vaccine. Metallic taste in mouth, tingling in back of throat, numbness in mouth and hands. Zyrtec given. Symptoms cleared within 45 minutes of receiving Zyrtec. 4 hours post vaccine arm pain at injection site, muscle aches in other arm and joint pain in hips. Fatigue and neck rigidity. All symptoms resolved after 48 hours post vaccine.

After vaccine was administered throat and tongue started tingling and worsened as 10 mins later. I was administer Allegra. After Allegra, I started getting redness and blotchy in my neck, jawline and abdomen. After 1 hour the Allegra lessened the redness and throat and tongue tingling. Next day 1/8/21 I had a fever, chills, nausea, headache and body aches. All reported to PCP.

At time of injection, left arm was sore and small welt appeared that went away after about 3 days. On 1/6/2021 I noticed a welt at injection site that was hot and felt hard. Welt has continued to spread on arm, some elbow and arm pain on left arm.

Caregiver (CG) received the Moderna Vaccine ( lot # 037k20a) and the next day had high fevers and severe angioedema in my mouth and lips. I contacted employee health and my manager and made an appointment to see my PCP. Worked on 01/02/2021 and received the vaccine around 0800. CG is a NP and self-prescribed prednisone 50mg X2 days, ending 01/05/2021 which has improved the swelling. CG was planning to follow up with her provider 01/06/2021-notes not available in icentra @this time. CG is planning NOT to receive 2nd shot. CG missed work r/t SE. LOA packet sent to CG

Complaining of left deltoid site pain hot and red. Pt complaining of fatigue and feelings of SOB overnight when laying flat on back. Complaints of heat sweats overnight. States this morning she is not having SOB, but having pain from left elbow up to shoulder injection site. States no visible rash other than injection site redness. Encouraged to call 911 if she has SOB that is unrelieved. Also stated that she is having Headaches that are not relieved by tylenol. Gave pt a list of normal reactions including, headaches, body aches, fever, fatigue. Encouraged her to alternate tylenol and Ibuprofen for body aches and headaches. Encouraged pt to call 911 with SOB that is not relieved. Contacted physician.

Day one left arm slightly swollen and sore. Day 2-3 redness present with soreness. small lump under skin. Headaches Day 4 redness growing in size (about size of quarter) with hard nodule under skin Day 5-10 enlarging redness (about 2.5inches by 2 inches diameter) dark red ring present with central clearing. Area is warm to touch.

Fatigue Painful arm- both to touch and w/ mobility Unable to lift arm w/o extreme pain Swelling- localized at inj site Warmth- at inj site Numbness (minimal) in L hand Hand- slight redness

Injection site became warm, swollen, and itchy 8 days after vaccine received. Still experiencing these symptoms 9 days after vaccine received.

Milder sx initially with sore arm, myalgia's, subj. LGT. Lasted a couple of days and fine for 3 days. About 48+ hours ago developed HA, fever LG, myalgia's, and last night noticed oblong area of erythema and induration of right upper arm (14 cm x 9.5 cm). Warm, red , slightly tender to touch. No fluctuance. Seemed a bit better at time of visit and no fever in past 24 hours. Feeling better today. Size as above, confluent induration, mild warmth, erythema but not as red as pictures the night before.

Moderna COVID-19 Vaccine EUA Started with a headache around 9pm. Severe arm pain around injection site. Body chills and then body sweats. Restless sleep. By 6am still had a headache and nauseous. Slept until 11am, awoke with a severe headache and light sensitivity and some nausea. Slept from noon until 3pm and had a slight headache. Headache has been off and on and is present but manageable at time of this report.

PT felt hot and itching. Redness to right arm, ears and face. Diphenhydramine 50mg/ml IM given RD. After Diphenhydramine was given and 30 min of observation. Client was free of reaction.

Patient is a 29 y.o. year-old female that presented to the clinic today for a Moderna COVID-19 vaccine.  Moderna COVID-19 vaccine was administered at: Time: 1820 Date: 1/8/2021   Patient presented with symptoms at time 1837. Patient's symptoms include the following:   Skin and Mucosal symptoms: Yes: Swelling of the throat and nose. Patient states that her nose started to feel funny and her throat was tight. She also noticed that her arm was red and swollen.   Respiratory Symptoms: No   Gastrointestinal Symptoms: No   Cardiovascular: No   The following actions were performed: Bendaryl 25mg administered as a single dose, patient brought to exam room by RN & MA. Vitals taken every 5 minutes while monitoring patient condition. At 1849 patient reported that her throat was feeling better. Patient had a localized reaction at the site of injection Left upper arm including redness, swelling and warm to touch. At 1903 RN reevaluated patient and reports that her redness is decreasing in her left arm and the throat/nose numbness was getting better. PA-C came into the room and evaluated patient. She said she sounds good and did not appear to be in distress. Patients husband drove her home after patient was monitored for approximately 40 minutes. Prior to patient leaving clinic RN advised patient of the 911/emergency room protocol . Patient verbalized understanding and was escorted out by RN to her car.   Incident reported to VAERS and database report completed   1/8/2021  

pt's arm at injection site became ithcy, red, and swollen. started on 1/6/2021, got worse on 1/7/2021, pt reports its a little bit better 1/8/2021. it is still swollen, not as itchy, not as tender to touch.

Client reported that on 12/30/2020 noted dime size red area around injection site then on 12/31/2020 noted golf ball size now was itchy and warm to touch then reported went away. On 1/5/2021 woke up with a red and swollen, hard area in same area that was itching and warm to touch. On 1/6/2021 Contacted Urgent Care and was seen and given Bactrim x10 days and instructed could put ice pack on area and to not receive dose #2. On 1/7/2021 noted area now looked like "bulls eye" reporting red in middle then white then red ring around it. Reports on 1/8/2021 area has faded, still see some redness with red border but no "bulls eye." Denied ever running a fever, having pain or overall ill feeling. Is currently on 10 days of Bactrim and Ibuprofen 600mg 3xdx2 days as directed by Medical Director. Client did take Benadryl on 1/6/2021 to help with itching and reported "it did help." Client will continue to follow up with her PCP at Medical Clinic as needed. No other issues reported at this time.

Rash & UrticariaPruritus Narrative: erythemic mildly pruritic rash 4 inches x 4 inches at left deltoid injection site tender touch, developed 1/5/2021. Taking zyrtec x 2 days in evening without relief of pruritis and Ibuprofen 1/7/2021 evening with relief of pain

patient developed large rash on chest. Nausea and vomiting. Also had tightness and scratchiness in throat but did not progress

Flushed red, tingling in left arm and left waist after the shot (10 minutes), arm soreness day after with fever (all day).

Insidious onset of left axillary pain on post-vaccine day 5, increasing in severity the following day. Worsened by arm movement, limiting function. No LAD. On post-vaccine day 7, a bright streak of erythema and severe overlying warmth developed at injection site. Erythema resolved the following day, warmth is still present. Also, typical injection site pain occurred day of vaccine and resolved over following two days.

Symptoms appeared on 12/31/20 with a sore arm, redness, warmth, and swelling at injection site. The reaction began to spread for the next 5 days. Throughout this time I was putting ice on it, taking Motrin, Benadryl, and applying hydrocortisone cream. The reaction went away for 2 days (1/5/21 and 1/6/21). The reaction then came back on 1/7/21. I went and saw my healthcare provider on 1/7/21, and was told it was a localized reaction and to continue to monitor it. I still have this reaction to this day, 1/10/21.

12/29/20 Dose #1 COVID (Moderna) administered at approximately 1:00pm. At approximately 8:00pm, patient experienced red blotches an swollen feet which resolved on 12/30/20. On 01/06/21, patient experienced swelling, redness and itching at injection site.

Chest pain at 1/10/2021 at 9:18pm - 9:25pm nothing provoked this dull pain in center of chest. Sitting in a chair before and after it stopped. New onset of itching, redness, and swelling at the injection site on 1/11/2021 at 0530 am. No other swelling, itching, redness anywhere else.

Day 6 after vaccine had tenderness in left armpit, the evening of day 7 noticed a rash the about 1.5 inch in circumference over injection site, accompanied by swelling, hardness and heat to touch. Day 8 the rash has increase to 2 inches in circumference and the overall size and hardness became more defined. Lifting the arm has become painful.

Friday morning1/8/21 at 0645 when awaking it felt like my right nostril was congested and it was hard to breath, also the tip of my nose was bright red, swollen and tender to touch. throughout the day the swelling, redness and pain increased with the right side of my nose. breathing did get easier. Saturday 1/9/21 the right side of my nose was still presenting with symptoms listed above and continued to grow toward my right eye. Sunday 1/10/21 the swelling increased but redness and pain stayed the same as the previous day. Ice was applied with mild improvement. No medication was taken. Monday 1/11/21 swelling on the right side of the nose has slightly gone down, minimal swelling (puffiness) under the right eye had started.

Injection site swelled (4" diameter), was extremely hot to the touch, and very painful start about four hours after the shot. By that evening, I was extremely achey and feeling flu-like symptoms. Extreme headache began next day and lasted for 1.5 days. Fever was never confirmed, but I had chills and could not warm myself. Swelling and redness lasted two days. Swelling was circular around injection site--still swollen now/4 days after. Aches lasted about 2 days. Once the redness subsided, the injection site became extremely itchy and still is to date. Please note, I am 10 months postpartum and still breastfeeding.

Itching started on right foot on Monday evening, January 4th 2021. By Tuesday evening both feet were itching and toes were red and inflamed along with the itching. I used hydrocortisone cream on them starting Wednesday evening. I contacted Dr. (tele health doctor) on Saturday evening and showed pictures of my feet. I was told it appeared to be "covid toes" and I may have COVID or an adverse reaction to the COVID vaccine. I was swabbed for COVID Saturday night. COVID results were negative. I was told to report my symptoms and reaction to CDC due to it being a reaction to the COVID vaccine. Currently it is January 11, 2021 and my feet are not itchy, just a little redness on my toes. I am continuing to monitor.

On the morning of 1/10/21, approximately 2 weeks after receiving the injection, and 2 days after testing positive on COVID-19, I developed a splotchy rash on my left arm at and around the injection site. Initially the rash did not itch, but as the day progressed, the rash became itchy. It is raised, red, and warm to the touch. I took liquid benadryl before going to bed that evening, but when I woke up this morning (1/11/21), the rash is still there and it does still itch on ocasion.

One hour after injection arm pain, fever, chills, body ache, headache Next day arm color and texture around site changing, all previous symptoms remain 3 days after fatigue and pallor 4 days after rash and discoloration forming around injection site

pt developed immediate (within minutes) redness of face; redness extended to arm and to neck, back of neck and now is concentrated on front of neck with an area of dry skin on temple; the areas affected burned for several hours;

"Tingling sensation in left elbow. Feels like I've been laying on it. Event started approximately 5 minutes after injection and is getting better now."

Five days after vaccine dose I started with axillary swelling on left side. Then I started having progressive redness, swelling and itching at injection site. By day 8 (after vaccine) I had a 4x4? hard lump at injection site spreading from my deltoid to my elbow. Numbness and tingling in hand. Swollen, palpable lymph nodes in left armpit. Treated with Keflex and Zyrtec. Symptoms improved after 2 days on antibiotics and resolved after 7 days with the exception of tenderness and soreness which is ongoing. There was question if the vaccine was given too low and how much was in deltoid.

Following the administration of the 1st dose I felt soreness on my arm. 2 hours later felt a sore throat, body aches, headache, fatigue set in. No skin reaction as of yet. The sore throat, body aches, and headaches resolved in 24 hrs. The sore arm and fatigue persisted. 4 days after receiving the shot (1/4/21) I woke up to an itch on my right arm in the exact location where I received the vaccine. The itch persisted and grew over the following days. I also felt fatigue, soreness in my right side of my body and poor appetite throughout the week. The redness and swelling set in 1/7/21 a few days after first noticing the itch. 1/8/21 was the peak with the redness, swelling and itching being at its height. I spoke with my PCP on 1/8/21 who suggested I used an over the counter allergy medicine to treat the swelling. I took Claritin. The fatigue, soreness in my right side of my body and poor appetite continued until 1/10/21 when I began to feel more ok. The swelling, redness and itching is slowly resolving. Today 1/12 the area is not swollen, redness is very minimal and itching minimal as well.

Herpes zoster in C2 distribution on left. Prodrome for three days starting day after vaccination with lesions developing 4th day after vaccination.

Hives, nausea, vomiting, fever 101, fatigue, lasted 2 days. Has had sever reactions to vaccines in the past.

I Received my COVID vaccine the evening of 12/22/20 and I had a sore arm for 1-2 days. Then I Developed itching, swelling and some redness over the area where the injection occurred on 12/29.

Lots pain, redness, large bruising in the area, trouble sleeping, intense burning at the site/ all in my upper arm area. pain has traveled into my underarm/swollen in that area, arm has become "numb" feeling, losing grip strength, can hardly hold my 20 pound weight while working out when a 35 pound dumbbell was easy prior to this. chest/back pain has gotten worse also. It all started with the bruising and then the trouble sleeping. I listed my symptoms as they occurred.

Moderna COVID-19 Vaccine EUA Evening of shot: pain at injection site 1 to 3 days after: pain at injection site, general achy-ness, severe fatigue, short dizzy spells, multiple headaches per day. All symptoms mostly treated by ibuprofen. 7 days after: tenderness at injection site, swollen and hard mound at injection site, mild to moderate hives at injection site. Mostly treated by ibuprofen and hydrocortisone cream.

On 1/11 in the evening, I noticed a red bump on my arm where I had received the vaccine. It was hard, but small. Then I woke up this morning (1/12), and my arm had a red rash, about 2-3 cm each way from where the vaccine was administered. It is itchy and warm. I have no other symptoms.

Patient describes after a couple weeks, the patient is experiencing soreness to touch, redness, pain and is "wrapping down" her arm towards her armpit. Also itchiness

Patient had COVID moderna vaccine on 1/4 with minimal side effects beyond some pain. Patient given Tetanus vaccine on 1/11 in opposite arm and the following day an large ovid erythematous patch at injection site for covid vaccine

Patient received the first dose of the covid vaccine on 12/30, and today 1/10/21 my arm has been itchy and I now have a round ring like rash on my arm near the injection site

Person called to ask about COVID vaccines reactions. Is having tingling on one side of the body along with fever, fatigue, flushing, nausea, and a rash

Received vaccine on 12/31/2020 and on Friday, 01/8/2021 I noticed a red spot on my left shoulder lower than where I was given the injection of the vaccine. The red spot has gotten bigger over the past 4 days. It does not hurt or itch. I am going to see a dermatologist for further inspection of this spot.

Slept for 30 hours out of next 48 hours post vaccine. Hypersensitive nerves along bilateral upper extremities and lower extremities (tingling sensation -lasted ~8hours). Feeling of pre-migraine symptoms including nausea for 3 days post vaccine. Migraine on 4th day post vaccine.

The day after the injection I had periods where the injection sight was warm to the touch (noticeably different temperature than the rest of my skin on my upper arm). By midmorning my left upper arm was very tender and extremely painful to the touch, even my shirt touching my skin hurt. By mid afternoon I was very fatigued and had to leave work and took a three hour nap. By the end of the evening the pain was resolved.

approximately 1/7/2021 I developed a small rash at the injection site that I noticed around 8:30 pm. This rash was spotty and irregular in shape and did not itch, but was hot to the touch. The following morning the rash had grown into a 2 inch wide and 2 in long bright red rash that was raised and swollen. Still hot to the touch but no itching. As of today the rash is no longer fully red on the inside but has left a small red raised ring of the outline of the initial rash which appears to be spreading outward. Another coworker of mine also reported the same symptom 2 days after the onset of my rash developed. I attended a virtual visit with a physicians assistant to take an oral antihistamine for a few days to see if the rash subsides.

-Pt received COVID19 vaccine on 1/8/2021 in the morning. -Pt was initially observed for 30 minutes, given hx of anaphylaxis to Iodine. -Pt initially had no symptoms - no itchiness, itchy or watery eyes, rash, difficulty swallowing, itchy throat, swelling, chest pain, shortness of breath, N/V. -She came back a few hours later with one right chest wall hive and few hives on her left arm. -No respiratory symptoms. No other symptoms besides those few hives. -Pt was evaluated by myself and Nurse. -Pt was observed for another 30 minutes & given Benadryal IM 25mg. -Pt also took 2 500mg Tylenol. -Pt felt better and was then discharged

1/3/21 2100 slight rapid heart rate when laying down in bed. (Could of been anxiety) 1/4/21 0700 rash across chest, that lasted the day, when down with taking Benadryl Left deltoid pain, hard, red hot lump at 7 o'clock from injection site, that is still slightly present today 1/11/2021. 0830 noticed left side of face swelling, that continued into 1/5/21 Extreme fatigue and body aches that lasted 3 days Intermittent left arm tingling, and hand numbness since the vaccine.

Large erythematous area around injection sight. Swelling. Occured the following day after vaccination (1/6), resolved, then flared up in same spot on 1/12. Additional symptoms include pain at the injection site, and lymphadenopathy and pain in the left axilla.

Left arm sore, redness, swelling, numbness, tingling, decrease grip strength, painful,ollen glands in arm pit. Insomnia

Patient had an itchy arm in the night 8 days after the vaccine, she scratched it, the site of the injection became hot, raised, and red

Patient received the Moderna vaccine on 1/4. Her arm was sore the next day and she was also tired. She has a localized reaction (red/swollen). The redness/swelling/lump appeared 1/12. The arm is hot to the touch. She's had no fever or shortness of breath. The redness continues to spread (whole shoulder).

Since the initial injection given i have had a knot in my arm. the soreness is gone and i did not have any other symptoms after the injection. I still have the knot in my arm, it is itchy, some burning sensation, raised, red, and hot to the touch. again no other symptoms such as fever, muscle aches, and or fatigue.

itchiness at site of injection, redness, hot to touch and welt at injection site all 1 week post injection

itchy, red, warm, painful (similar to discomfort immediately after injection). Warmth and pain dissipated within 3 days, redness and intermittent itchiness remained through this point; but improved.

pain at injection site (left deltoid) radiating to left breast and then an eruption of erythema multiforme on chest, bilateral arms

tingling on the neck started 2 days out from vaccination and lingered through the 3rd day out, moderate pain of inejction site began 1 day out from vaccination and lingered for 2 more days

10 days post with still very red, warm spot around the injection site. Has gotten larger and more red over last 4 days

Aside from the chills, fatigue, headache, and feeling feverish the not so normal and quiet severe reaction I am still having is swelling and major redness at the injection site on my right arm. It also has moderate to severe itching . Was given steroids and an antibiotic but have seen no changes due to just starting the medications. Is it common and/or something to worry about?

At one am the night following receiving the injection I woke up with severe pain in my left arm where I received the injection. The pin radiated from elbow to shoulder. I had severe chills, vomiting, and uncontrollable shaking. I had body aches, headaches, and fatigue for the following two days from onset of symptoms. I had a confirmed case of Covid-19 on 9/8/2020 and my symptoms from the injection were at points more server than my symptoms from Covid.

Dizziness, headache, tightness of chest, hives, itching. Signs became apparent an hour to hour and a half of vaccine. Took antihistamine making tightness of chest and itching subside. Followed up with my doctor that Wednesday.

Forehead tingling neck tingling swollen lymph node same arm as the injection Injection site was swollen, red and warm to touch

I woke up with a rash on my stomach that were very itchy. They spread to chest, arm pit, forarm & inner thighs.

Local allergic reaction started overnight after first dose on 1/7/21. Noticed on morning of 1/8/21 that skin at injection site was itchy and a rash had broken out. By the next day, 1/9/21, the rash had grown larger, extremely red, and was hot to the touch. Drew a circle around the rash to monitor growth, took a Benadryl. By afternoon of 1/10/21, rash appeared to have grown slightly larger, but significantly less red and temperature and swelling had reduced. Seemed to be gone by 1/11/21. Tonight, 1/14/21, around 6:30pm, I noticed that the skin was itchy at the injection site again, and that a rash had begun to break out once more. Will continue to monitor it.

Received 1st vaccine 1/5/21. Arm was tender. Around midnight 1/6/21 my arm was very painful to the touch, move, awful. 24 hours later just sore. On 1/7/2021 I started to feel short of breath and run down. Sinus infection symptoms. I was sent home from work to get a COVID swab. That evening I lost my taste and began to feel achey. Negative test on 1/10/21. Saw urgent care on 1/9/21 for Covid swab and visit. He diagnosed viral and was sure I was positive. On 1/11/21 my energy returned and I wasn?t achey. Congestion and cough. By 1/13/21 felt fine other than lingering wet cough. This morning, 1/14/21 I noticed my arm itched and looked at it and I?ve got a small red rash around the injection sight and tenderness on palpation.

Within the first few minutes I have a weird taste in my mouth. It went away after a couple minutes. The day after getting the first dose (1/7/21) I felt like I was getting that flu all day. Went away day after that (1/8/21). On 1/14/2021 I noticed hives all around the injection site as well as a faded bruise.

- SORENESS AT INJECTION SITE FOR THE FIRST 2 DAYS AFTER VACCINATION - 7 DAYS AFTER VACCINATION, INJECTION SITE IS SWELLING, ITCHING, SORENESS AND WARM TO TOUCH. SELF ADMINISTERED 2 IBUPROFEN AND 1 DIPHENHYDRAMINE ON 01/14/21. - 01/15/2021 NO ITCHING. DELTOID MUSCLE STILL SWOLLEN AND PAINFUL

1 WEEK AFTER VACCINE NOTED SWELLING AND REDNESS IN ARM AT INJECTION SITE. 1 WEEK LATER SWELLING REDUCED

1/7/21 PM sore left arm at injection sight 1/10/21 PM severe congestion, headache, sinus pressure 1/11/21 AM severe headache, vertigo, shortness of breath, cough 1/11/21 AM went to get covid test due to being symptomatic, tested positive. I had a negative weekly (required by work) test done on 1/5/21 prior to getting vaccine.

After vaccine was administered, 4:40 pm, I was feeling my heart palpitating fast like an anxiety attack. I also experienced a headache, fatigue, body ache and arm pain that same day at 4:58 pm, and around 6:15 pm I my whole body was itchy. The next day January 12, 2021, I woke up with a fever of 100.2, still with body ache, headache, but no longer body itchiness. Yesterday January 14, 2021 and today January 15, 2021 still having headache, body ache pain did decrease.

I received Moderna vaccine on 01/06/2021. Normal pain at the injection site occured with little concern. Pain in armpit began 01/08/2021. I did not think anything of it, believing the pain to be from an ingrown hair caused by shaving or just something with the vaccine. I ignored it to spend time with family. On 01/12/2021 I noticed the pain had not subsided and deepened into the armpit causing pain to radiate from the area when lifting or moving heavy items. I palpated the area and felt a pea sized lump. It moved freely. I could not locate it again. I continued to palpate into the top of my shoulder and discovered a large lump in the clavicle area. It is painful to apply pressure. I knew these areas to be part of the lymphatic system. I also did research on side effects of the Moderna vaccine but observed most people to have lymph node symptoms for only 24-48 hours within three days of receiving the vaccine then they subside. I made an appointment that same day, 01/12/2021, with Dr. at clinic to be examined. At first, Dr was dismissive of my symptoms. Dr did physically examine my areas of complaint and scheduled an ultrasound for 01/15/2021 at Hospital. On 01/13/2021 I noticed the injection site began to ache again. On 01/14/2021 I awoke from a nap at 6pm. I began showering for work when I felt a burning, itchy sensation on my inner left bicep. I observed two red spots on my inner left bicep close to my armpit with a red rash below the two red spots. I palpated the red spots to find a large and slightly smaller lump under the skin corresponding with the red spots. The rash itches. As of 01/15/2021, the ultrasound had to be rescheduled by the hospital as their ultrasound technician cannot make it into work because of a blizzard. I now have two lumps in the clavicle area that alternate swelling and reducing in size. I've been taking tylenol every four hours when I'm awake to control the pain. The ones in my clavicle now cause tension in the left side of my neck. I've also applied warm compresses on the affected sites. It helps lessen the swelling for a bit but does come back.

Moderna COVID-19 Vaccine EUA Red, inflamed, hot-to-the-touch blotch has appeared surrounding the injection site. About an inch and a half in diameter. Appearance started 9-10 days post-injection. Patient also running a fever of 100.2. I'm reporting immediately so no treatment/outcomes yet.

Next day after vaccine administered, developed an area of redness, warmth, swelling at the injection site. Worsened over a period of a couple days & increased in size. Resolved for a few days. Then symptoms returned.

Patient presented to Pharmacy 8 days post COVID injection (1st dose) On Day 8 patients arm became red at injection site approximately 3 inches in diameter. Red and warm. Patient is medical student who had the NP onsite look at it and stated potential cellulitis. Patient referred to Urgent care for Medical Care.

Since receiving the shot I had a bump at the injection site. However, yesterday I started noticing that the bump was larger. Today I noticed that it's hot to touch and more like a welt that's larger than quarter size.

6 days after injection i developed redness and swelling of the injection site. It became very hard upon palpation. The area was hot to touch and continued to spread. The area has been marked with a sharpie and the redness continues to spread. It is Saturday so I have to wait until Monday for my primary care office to open for further treatment. Currently I am utilizing oral benadryl, benadryl cream, cold compresses, and ibuprofen.

7 days after vaccine, developed painful red swollen itchy lump at injection site that was warm to the touch. 8 days after vaccine the local reaction had same symptoms, but was a bit larger and not as circular in shape. 10 days after vaccine swelling was down, but red rash spread several inches down arm in irregular shape. 11 days after vaccine the rash was even larger and more spread down arm, irregular in shape, red, itchy, warm. Vaccine was administered several inches (4-5) lower down on arm than what is typical. Went to urgent care and they said it may be an allergic reaction and to try antihistamines. Advised to monitor the rash and return to doctor if rash spreads further or new symptoms occur. Ongoing.

Injection site pain began the night of receiving the vaccine and lasted for approximately 24 hours. I have now noticed a reddened area where I received the vaccine and it feels like a bump under the skin.

One week after injection arm became itchy at injection site. It started it a half dollar size rash, that has now doubled in size. The area is firm and itchy. Not really any pain.

Paralysis of arm injected, erythema and edema surrounding injection site. Mottled skin, headache, extreme fatigue, abdominal cramping, diarrhea. Onset 3 hours post injection. Over the counter meds, Tylenol extra strength , ibuprofen, Benadryl. 72 hours mostly resolved symptoms

Physical findings: Rash, Hives, Symptoms: shortness of air, throat swelling, felt faint. . BP, o2 sat fine., Pt did fine and was treated immediately with epi pen, benadryl, solumedrol and fluids.

Rash similar to Sulfa rash, started about 24-30 hours after first shot (taken in my left arm). I noticed an eczema style patch on my right hand then shortly after my arms started resending and looking splotchy. I had a sulfa rash reaction to a steroid in 2009 that also showed up after a day or two so I recognized it and started taking Benadryl. It seems to be helping but not completely clearing the rash. My blood pressure was also high this morning, which is abnormal for me.

Swelling and rash of left arm. Pt states four other team members with same lot number developed similar issues in the same time frame

Arm soreness at injection site for first 48 hours after shot. 1 week after shot experienced 12 hours of chills and low grade fever. 9 days after shot developed swollen lymph node at collar bone on left side (same side as shot). Lymph a bit painful and swollen lymph node has lasted 1 week so far.

Got vaccine 1/9 1/12 - Second day at 3amI had extreme nasuea, almost threw up. medium stomach pain during the day, I was constipated that whole day. Finally constipation ended at 7pm. 1/13 - 1/15 arm was sore, felt like pulled muscle, very slight, vaccine injection spot was slightly raised 1/16 - injection spot was very itchy, very inflammed, very red and hard, hot to the touch 1/17 had stomach issues and fatigue, arm less inflammed but still red and hard and warm.

Left armpit/axillary soreness 1 week after recdiving vaccine which has not dissipated and a red raised area of erythema to the left deltoid which appeared 1?week after injection

One week after getting injection my arm at injection site had red circular rash with diameter close to size of a lime. Itching, redness, slight swelling. Applied over the counter hydrocortisone cream to help with itching and tea tree oil twice the weekend after rash appeared. Today rash is improving.

1 week after injection I started to experience redness, itching, and swelling around the injection site. It is thought to be a delayed allergic reaction.

Approximately 1 week post dose, I woke up with significant skin redness around the injection site about 1 inch wide by 3 inches long. I did not experience any injection site skin reactions prior to this, just muscle pain in that shoulder for a couple days after the dose. The redness faded away within 24 hours.

Area where injection was given was red and swollen. Resolved by 1/16/2021. Reoccurred 1/19/2021. Larger site reaction 1x1 inch. Red, tender, nodule "golf ball" size. Minor itching. No streaking. w/o fever, no tingling

Circular area of erythema on right upper arm. Just started today. Has some mild erythema in patches above the area. Says it itches.

Delayed local reaction on day 6-7 of redness, Induration, itching, mild tenderness at site of injection. Redness about 4cmX5cm. 18 weeks pregnant Due date: 6/23/21

Fatigue, congestion, headache, sinus pressure, pruritis/erythema/welting below injection site measuring 7.6cm x 4.5cm

I received Moderna COVID vaccine at 1200pm on 12/24/2020 At about 0300 on 12/25/20, I awoke from sleeping with palpitations and a heart rate of about 140. Increased heart rate of 120-150 continued for a couple of hours with minimal dizziness. About 5am, I had a bought of sudden explosive, watery stool. This continued 3 more times in the am, at times having incontinence. (This has never occurred before.) By 10 am, those symptoms had stopped. Only residual side effects were a headache and sore arm. On 12/31, it was noticed that I had hives on my abdomen and back. They were not itchy and I am unsure how long they had been there for; referred to allergy

On January 19, one week after I got the vaccine, the area of vaccination got swollen, red, and was in pain. I took ibuprofen and used an ice pack to bring down the swelling. On January 20, the swelling got down but there is still redness and slight pain when I lift my arm. I will call my primary care doctor today to get more information.

Severe headache since 1-11-21. Knot in arm at injection site. (Ongoing) Last night (1-19-21) I noticed injection site was hot and had redness. (Ongoing)

Site was sore after vaccination for 2 days. 6 days after vaccination on 18Jan, patient started experiencing urticaria, redness, and edema around localized injection site. 6.5x4.5cm. Patient states redness/swelling has not increased. Patient tried cocoa butter and lotion to prevent itching, both topicals were ineffective. Patient applied topicals around injection site, to avoid direct application to injection point.

Swelling in the L axilla several days after vaccination followed by a warm sensation and swelling at the injection site 5 days after vaccination with subsequent development of numbness and tingling of the L hand that resolved in a week.

The day of my first vaccination, I got a painful red lump at the injection site and it was warm to touch. Today is 1/20/21 and I'm still experiencing the same reaction- it hasn't gone away, the red lump is less swollen and warm to touch. I also experienced moderate fatigue and weakness, constant headache, and loss of smell and I'm still experiencing these symptoms.

Warmth, erythema, and swelling to a half dollar on right arm where vaccine was administered occurred x4 days after injection, By day 8 (15 Jan 2021) swelling resolved to a quarter size but had accompanying itching. Itching is still ongoing as of today 20 Jan 2021. Used betamethasone cream which helps somewhat with itching

client reported tingling sensation down the left arm 15 minutes after vaccination; seen & cleared by EMS. B/P- 125/75, P- 87

client reported tingling sensation down the left arm approximately 15 minutes after vaccination; seen & cleared by EMS. B/P-125/75, P-87

1/22/2021: Delayed reaction - mild, itchy rash spreading on/around injection site (about 2 to 3" diameter) Day 1-3: Extreme soreness/sensitivity at injection site Day 6: Mild sensitivity at injection site, notice site around it turned pink Day 7: New rash spreading on/around injection site

Anaphylaxis treated at Tufts Medical Center -Full body hives on 1/21- treated w Benadryl, Claritin, Famotidine -1/22 woke up with lip swelling, throat itching, lip tingling- came to ER on this date for evaluation, given epinephrine IM, Benadryl IV, fluids IV, prednisone PO

I developed a red mark at the site of injection by the next day. Over the course of 7 days it quadrupled in size, became swollen, red, warm, itchy and painful with pressure. By day 11 it was beginning to consume my upper arm and I contacted my PCP. He filled a prescription for a steroid (Methylprednisolone 4mg) and day two of taking steroids swelling and itchiness had gone down.

I received the vaccine on 1/19/2021 at my place of employment. Upon getting the vaccine approx 30 minutes after receiving i became very itcy, and my lips were burning/tingling. The itching continued to get worse, forming red rash on my chest. I called my MD at this point. I was told to take benadryl and to go to er if it became worse. I took benadryl. the itching continued for 2 days. i also experienced pain at injection site, headache, nausea, diarrhea, extreme fatigue, muscle soreness. on 2nd day after vaccine i woke up and my muscles continued to be very sore. like i had just completed a marathon. I also have this sensation that started with the increased muscle pain. The only way i can explain it is that it feels like how a TENS unit feels, but its coming from the inside. especially in my back and thighs. this continues. i feel like i could just start shaking at any time. i cannot sleep but i am so tired. i was seen at dr today and i was told to report this to you guys. this sensation has not went away and has actually cause my muscles to spasming. MD said the vaccine effected my muscles and possibly neurologically as well.

Intially pain at site, muscle aches, fatigue, headache, chills; but a week later a rash that is spreading outward from the injection site.

Itching since the vaccination day and rash appeared 9 days after the vaccine (1/21/2021) and getting bigger.

My arm after the shot about 3 hours got hot red and swollen around the shot site. I am a week out from my first dose and I had the same reaction again below the shot site localized to the skin it seems(hot,red and swollen)

Soreness and fatigue a couple hours after injection and only lasted a couple days. Redness and heat sensation at injection site persisted, but was mild. Around 1/15, about a week after injection redness and swelling suddenly increased with new onset itchiness. Applied ice pack and while swelling significantly went down, and has stayed down, the redness lightened and dispersed into almost a faint bullseye. Redness continues to dissipate but still present in faint bullseye shape.

That night it was just a mild soreness similar to any other vaccine at the injection site. Monday the 28th I woke to go to work and I could not taste anything. Instead went to get tested for covid and the result was positive.

Within 5 minutes heart rate increased to 175bpm, hives appeared on my chest, neck, and back. Dizziness and severe nausea started and blood pressure decreased. Trouble concentrating and tingling in hands and feet. I was taken to the Emergency Room and hooked up to an IV and Heart Monitoring. I was given IV Benadryl, Prednisone, Pepcid, and Zofran. I was going to get an injection of Epinephrine but my heart rate and blood pressure increased significantly after the first batch of IV meds and they were concerned that the Epinephrine may have made things worse. I was monitored for 4 hours and then discharged with instructions to take Benadryl 50mg every 6 hours for 5 days, Prednisone 60mg every day for 5 days, Pepcid 40mg twice a day for 5 days and given a prescription for an Epi-Pen. I remained very nauseous and dizzy foe the next 48 hours. My injection site became swollen, red, and tender 48 hours after my injection and then re-flared up 11 days after my injection on 01/17/21.

Experiencing severe soreness, tingling from clavical to thumb and shooting pain in shoulder/arm following receipt of the COVID vaccine. Limited range of motion and difficulty carrying out daily tasks. REACTON Type – Neuralgia.

I got hives and rash one week after my first dose on my left arm. the rash expanding up to my arm. It took 4 days to go away. the instructions from my doctor was to take Benadryl and cold compresses.

"When I was leaving for work on Thursday 1/14 (8 days post vaccine) I noticed my arm was sore and heavy, almost like I got the vaccine all over again. When I got to work, I looked at my arm and it was very swollen, red, warm, firm, and itchy. By Sunday 1/17, I started to see progress with the swelling, warmth and redness. It is still mildly itchy. Please note, when I got the vaccine on 1/06/21, I had the normal side effects of arm soreness, fatigue, mild muscle aches and a mild headache; all of these symptoms were gone by Friday 1/08/21. I saw [vaccine administrator] and she instructed me to use ice and hydrocortisone cream. I iced it for 4 days and there was no change until day 4 (Sunday). I also used Aleve during this time as well. I saw my PCP on Monday 1/18 and she told me to continue the current treatment of ice and Alieve and to update her on Wednesday 1/20."

1/23/21 10 AM-got out of shower and noticed left arm injection site was red and swollen and noticed it started to spread. Pt. states that the size of her arm swelling and redness is about the size of dollar bill and spreading. Pt. states that her left arm is really itchy. Pt. states that she started experiencing chest tightness on 1/18/21. She was seen by her cardiologist and echo was performed and reportedly normal. Pt. states that her chest tightness is still present and is going to make appt with pcp to have chest tightness evaluated. Pt. denies taking anything for her symptoms.

About 9 days after receiving the vaccine, I started getting redness, bumpiness, and itchiness just around the injection site. The redness has increased over the last day or so. The spot is also hot to the touch. Otherwise, I am feeling fine.

1/12/21 received the vaccine and had mild symptoms of injection site pain and LGF. By morning of 1/13/21, c/o fever up to 103.4, joint pain, especially in spine, dry heaves/nausea, dizziness and metallic tastes. Symptoms resolved within 2 days.

Arm swelling, hot to touch, and soreness within 12 hours after. Soreness and warmth at injection site continued for 10 days. 24 hours after injection, numbness and tingling started and still hasn't resolved 2 weeks after injection. Decreased strength in right arm, pain and discomfort comes and goes through day and night. Arm will go numb for up to an hour making it hard to grasp items, write, type, ect. Took Tylenol and Benadryl every evening, applied ice , stretching and movement to work muscle. Appears that vaccine was given too low instead of 2 in from shoulder, given 6 in from shoulder by pharmacist

Dizziness; Blood pressure 140/98; Pulse 123; Nausea; Numbness to her body; Chest tightness; Abdominal discomfort; Felt like she was going to pass out; Developed blotchy skin to chest and neck area within minutes of injection; Heart racing; Weakness; A spontaneous report was received from a consumer concerning a 29-year-old, female patient who experienced numbness, chest tightness, abdominal discomfort [Abdominal discomfort], felt like she was going to pass out, blotchy skin to chest and neck area [Rash macular], racing heart [Palpitations], weakness [Asthenia], dizziness [Dizziness], blood pressure 140/98 [Increased blood pressure], pulse 123 [Tachycardia] and nausea [Nausea]. The patient's medical history included asthma and there were no known drug allergies. Additionally, it was noted that there was no history of anaphylaxis. Concomitant product use included cetirizine and ibuprofen. On 22-Dec-2020, a short time prior to the onset of the symptoms, the patient received their first of two planned doses of mRNA-1273 (Lot# 011J20A}) intramuscularly in the left arm for prophylaxis of COVID-19 infection. Following vaccination, the patient immediately developed numbness to her body, chest tightness and abdominal discomfort. She remained alert and oriented but voiced concern that she felt like she was going to pass out. She developed blotchy skin to the chest and neck area within minutes of injection. Her vital signs included blood pressure of 140/98 and a pulse of 123. She was given water to drink which she tolerated well. She continued with symptoms of nausea, blotchy skin, heart racing and weakness. Dizziness was also reported. She was taken to the Emergency Room. Treatment for the event included epinephrine, methylprednisolone sodium succinate, diphenhydramine and lorazepam. Action taken with mRNA-1273 in response to the events was not provided. The outcome of the events was reported as recovered.; Reporter's Comments: This case concerns a 29 year-old, female patient with medical history of asthma, who experienced events of numbness, chest tightness, abdominal discomfort, felt like she was going to pass out, blotchy skin to chest and neck area, racing heart, weakness, dizziness, nausea, blood pressure of 140/98 and pulse of 123. The events occurred immediately after the first and last dose of mRNA-1273 vaccine administration. The patient was taken to the Emergency Room and recovered after receiving epinephrine, methylprednisolone sodium succinate, diphenhydramine and lorazepam. Based on the current available information and temporal association between the use of the product and the start date of the events, a causal relationship cannot be excluded and the events are assessed as possibly related.

I started my period 2 days after the vaccine (I have very irregular periods and hadn't had one in over 6 months). Today, day 8, I woke up to a red, hot, and very itchy injection site. My skin feels thick and almost like there are a lot of little bug bites concentrated in a palm-sized circle on my arm.

Muscle Aches, headache, low grade fever (responding to tylenol), slight itching and redness at injection site.

Redness, swelling (lump), itching, and warmth in area of injection. Symptoms have continued a week plus after receiving vaccination

Skin change 10 minutes after getting the vaccine. Numbness on my tone. A few dates after skin change came back. I am feeling dizzy. Without energy

Chills, fever, pounding headache, myalgia, severe pain at site of injection. Racing heart. Could not sleep

I was 11weeks and 2 days pregnant at time of injection. EDD 08/15/2021. The day after my vaccine, I had fever, chills, bodyaches, headache and fatigue. The following day, I woke up with a rash just on my face. It is not itchy or painful.

"Moderna Covid-19 Vaccine EUA" - On 1/25 evening my arm pit area in the arm I received the injection is began to feel tender and a little painful. Late that night my injection site started to become red, swollen, hard, hot to the touch, and itchy. As of 1/29, arm pit area is less tender and not painful, and injection site reaction is improving (swelling as gone down, still a little red but noticeably better).

15 minutes after vaccine administration, pruritis to throat and upper chest. No shortness of breathing, urticaria, edema.

Day 1-3: red injection site, sore arm and body aches, fatigue Day 4-5: red injection site but otherwise fine Day 6-7: red injection site hot to touch, itching, getting larger Day 8: injection site 4? diameter red swollen, itching and burning (COVID arm)

Developed mild swelling, mild itchiness and redness on left lower arm , not on injection site after 8 days of vaccination.

Employee started to have an itchy/tingling mouth about 10 minutes following vaccine administration. She was given diphenhydramine, which helped alleviate the symptoms. As the day went on she developed hives on her neck, chest, back, arms and hands. She continued to take Benadryl every 4-6 hours and all symptoms were gone within 24 hours after vaccination.

Had vaccine at 310p on 1/26/21. On 1/28/21 around 9p, noticed a red rash/welt on left upper arm near injection site. Warm to touch, not itchy. Unchanged in 12 hours. Some tenderness in left axilla.

Painful, red rash developed to area where shot was administered 8 days after shot given. No pruritus, but burning pain.

Patient developed hives/rash on chest and arms immediately after receiving vaccine, administered 50 mg Benadryl po, took vitals twice fifteen minutes apart and was then driven home by her husband. Vital signs remained stable throughout episode.

Pt is a 29 yo who was given Moderna vaccine at 09:03 AM. 11:30 AM: Adverse effect symptoms : Itching all over the body, dizziness, itchy throat. 12:10PM: Benadryl 50mg IM given 12:25PM: V/S: B/P= 143/109, T=93.9, Pulse =92, RR= 24, Spo2=99%. 12: 30PM: Emergency Medical called 01:30PM . V/S: B/P=140/89, T97.1, Pulse=88, RR=24--Pt verbalized the itching stopped including itching throat, no more dizziness. Pt walked out of facility with no assistance.

The vaccine was administered on the following date: 1/19/21 and at approximately the following time: 1:00PM The symptoms began 36 hours after administration of the vaccine. The symptoms were: hives (itchy red raised rash - see photos), lip swelling and throat itching. Tried to treat at home with Benadryl but didn't improve so went to ED. The treatment of the reaction was: o Antihistamines: Benadryl o Steroids: steroid in ED and 5 day course of prednisone o Epinephrine: 1x